Patents by Inventor Gary C. Chamness

Gary C. Chamness has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heat shock/stress response proteins and prognosis in cancer
    Patent number: 5447843
    Abstract: The invention relates to a method of predicting disease-free survival in cancer patients by relating the number and amount of stress response proteins in cancer tissue to the probability of tumor recurrence. Particular heat shock/stress response proteins useful in the determination of tumor recurrence are the stress response proteins, hsp70, hsp90, hsp27, and glucose regulated protein grp94. Specific levels of the stress response proteins relative to an internal standard are identified, above which the probability of tumor recurrence is highly significant. Kit methods are disclosed which could enable determination of the stress proteins by an antibody assay.
    Type: Grant
    Filed: November 25, 1992
    Date of Patent: September 5, 1995
    Assignee: Board of Regents, The University of Texas System
    Inventors: William L. McGuire, deceased, Gary M. Clark, Gary C. Chamness, Atul K. Tandon, Suzanne A. Fuqua
  • Method and kit for the prognostication of breast cancer patient via heat shock/stress protein determination
    Patent number: 5188964
    Abstract: The invention relates to a method of predicting disease-free survival in cancer patients by relating the number and amount of stress response proteins in the cancer tissue to the probability of tumor recurrence. Particular heat shock/stress response proteins useful in the determination of tumor recurrence are the stress response proteins, hsp70, hsp90, hsp27, and glucose regulated protein grp94. Specific levels of the stress response proteins are identified, above which the probability of tumor recurrence is highly signficant. Kit methods are disclosed which could enable determination of the stress proteins by an antibody assay.
    Type: Grant
    Filed: April 12, 1990
    Date of Patent: February 23, 1993
    Assignee: Board of Regents, The University of Texas System
    Inventors: William L. McGuire, Atul K. Tandon, Gary M. Clark, Gary C. Chamness