Patents by Inventor Gary C. Starling

Gary C. Starling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-2 MUTEINS FOR TREATING CANCER OR INFECTION
    Publication number: 20240309061
    Abstract: Provided herein are IL-2 muteins that bind to the IL-2 receptor ? subunit but do not have measurable binding to the IL-2 receptor a subunit. Also provided are compositions, kits, methods, and uses involving such IL-2 muteins.
    Type: Application
    Filed: July 21, 2022
    Publication date: September 19, 2024
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Juan C. Alvarez, Alan C. Cheng, Ghassan N. Fayad, Brian E. Hall, Veronica M. Juan, Peter S. Kim, Sheila H. Ranganath, Venkataraman Sriraman, Gary C. Starling, Nicole C. Walsh
  • Novel immunoglobulin superfamily members of APEX-1, APEX-2 and APEX-3 and uses thereof
    Publication number: 20020123617
    Abstract: The present invention provides the nucleotide and amino acid sequences of apex-1, -2, and -3, encoding novel APEX proteins APEX-1, APEX-2, and APEX-3, which are novel gene members of the CD2 subgroup of the immunoglobulin superfamily.
    Type: Application
    Filed: December 22, 2000
    Publication date: September 5, 2002
    Inventors: Gary C. Starling, Joshua N. Finger
  • Monoclonal antibodies to human CD6
    Patent number: 6372215
    Abstract: The invention provides antibodies and other binding agents that bind specifically to SRCR domains of human CD6 (hCD6) and have advantageous properties, including the capacity to substantially inhibit binding of activated leukocyte adhesion molecule (ALCAM) to hCD6. The binding agents of the invention are useful, inter alia, in methods for screening peptides and drugs that also bind to hCD6 and/or modulate ALCAM binding to hCD6, as well as in diagnostic and therapeutic methods for management and treatment of inflammatory and autoimmune diseases.
    Type: Grant
    Filed: February 25, 1998
    Date of Patent: April 16, 2002
    Assignee: Bristol-Myers Squibb Company
    Inventors: Gary C. Starling, Anthony W. Siadak, Michael A. Bowen, Alejandro A. Aruffo, Jurgen Bajorath, Dale L. Bodian, John E. Skonier