Patents by Inventor Gary Conard Visor

Gary Conard Visor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FORMULATIONS OF A COMPOUND MODULATING KINASES
    Publication number: 20220184079
    Abstract: Provided are solid dispersions of Compound I having the formula: wherein Compound I is substantially amorphous, methods of manufacturing said solid dispersions, and methods of using said solid dispersions.
    Type: Application
    Filed: March 2, 2022
    Publication date: June 16, 2022
    Inventors: Hamid Rezaei, Marika Nespi, Prabha N. Ibrahim, Gary Conard Visor
  • SOLID FORMS OF A COMPOUND MODULATING KINASES
    Publication number: 20220153737
    Abstract: Solid forms of the compound, [5-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-(6-trifluoromethyl-pyridin-3-ylmethyl)-amine HCl salt (Compound I) and its free base, active on the receptor protein kinases c-Kit and/or c-Fms and/or Flt3, were prepared and characterized: Also provided are methods of using the solid forms.
    Type: Application
    Filed: November 24, 2021
    Publication date: May 19, 2022
    Inventors: Prabha N. Ibrahim, Gary Conard Visor
  • Formulations of a compound modulating kinases
    Patent number: 11103505
    Abstract: Provided are solid dispersions of Compound I having the formula: wherein Compound I is substantially amorphous, methods of manufacturing said solid dispersions, and methods of using said solid dispersions.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: August 31, 2021
    Assignee: Plexxikon Inc.
    Inventors: Hamid Rezaei, Marika Nespi, Prabha N. Ibrahim, Gary Conard Visor
  • Formulations of a compound modulating kinases
    Patent number: 10961240
    Abstract: Provided are compositions comprising Compound I having the following structure: or a pharmaceutically acceptable salt thereof, and a solubilizing agent; methods of making the same; and methods of using the same.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: March 30, 2021
    Assignees: Plexxikon Inc., Daiichi Sankyo Company, Limited
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Gary Conard Visor, Tomoari Kamo, Hiroshi Yamakose
  • Formulations of a compound modulating kinases
    Patent number: 10941142
    Abstract: Provided are compositions comprising Compound I having the following structure: or a pharmaceutically acceptable salt thereof, and a solubilizing agent; methods of making the same; and methods of using the same.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: March 9, 2021
    Assignee: Plexxikon Inc.
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Gary Conard Visor, Tomoari Kamo, Hiroshi Yamakose
  • Solid forms of a compound modulating kinases
    Patent number: 10584122
    Abstract: Solid forms of the compound, [5-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-(6-trifluoromethyl-pyridin-3-ylmethyl)-amine HCl salt (Compound I) and its free base, active on the receptor protein kinases c-Kit and/or c-Fms and/or Flt3, were prepared and characterized: Also provided are methods of using the solid forms.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: March 10, 2020
    Assignee: Plexxikon Inc.
    Inventors: Prabha N. Ibrahim, Gary Conard Visor
  • FORMULATIONS OF A COMPOUND MODULATING KINASES
    Publication number: 20200010465
    Abstract: Provided are compositions comprising Compound I having the following structure: or a pharmaceutically acceptable salt thereof, and a solubilizing agent; methods of making the same; and methods of using the same.
    Type: Application
    Filed: July 12, 2019
    Publication date: January 9, 2020
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Gary Conard Visor, Tomoari Kamo, Hiroshi Yamakose
  • FORMULATIONS OF A COMPOUND MODULATING KINASES
    Publication number: 20190337944
    Abstract: Provided are compositions comprising Compound I having the following structure: or a pharmaceutically acceptable salt thereof, and a solubilizing agent; methods of making the same; and methods of using the same.
    Type: Application
    Filed: July 12, 2019
    Publication date: November 7, 2019
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Gary Conard Visor, Tomoari Kamo, Hiroshi Yamakose
  • Formulations of a compound modulating kinases
    Patent number: 10435404
    Abstract: Provided are compositions comprising Compound I having the following structure: or a pharmaceutically acceptable salt thereof, and a solubilizing agent; methods of making the same; and methods of using the same.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: October 8, 2019
    Assignees: Plexxikon Inc., Daiichi Sankyo Company, Limited
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Gary Conard Visor, Tomoari Kamo, Hiroshi Yamakose
  • Solid forms of a compound for modulating kinases
    Patent number: 10316032
    Abstract: Solid forms of Compound I (and its S-enantiomer, Compound II), active on protein kinases, were prepared and characterized: Also provided are methods of using the solid forms.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: June 11, 2019
    Assignee: Plexxikon Inc.
    Inventors: Prabha N. Ibrahim, Gary Conard Visor
  • FORMULATIONS OF A COMPOUND MODULATING KINASES
    Publication number: 20190125747
    Abstract: Provided are solid dispersions of Compound I having the formula: wherein Compound I is substantially amorphous, methods of manufacturing said solid dispersions, and methods of using said solid dispersions.
    Type: Application
    Filed: October 26, 2018
    Publication date: May 2, 2019
    Inventors: Hamid Rezaei, Marika Nespi, Prabha N. Ibrahim, Gary Conard Visor
  • SOLID FORMS OF A COMPOUND MODULATING KINASES
    Publication number: 20190119273
    Abstract: Solid forms of the compound, [5-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-(6-trifluoromethyl-pyridin-3-ylmethyl)-amine HCl salt (Compound I) and its free base, active on the receptor protein kinases c-Kit and/or c-Fms and/or Flt3, were prepared and characterized: Also provided are methods of using the solid forms.
    Type: Application
    Filed: December 13, 2018
    Publication date: April 25, 2019
    Inventors: Prabha N. Ibrahim, Gary Conard Visor
  • FORMULATIONS OF A COMPOUND MODULATING KINASES
    Publication number: 20190031654
    Abstract: Provided are compositions comprising Compound I having the following structure: or a pharmaceutically acceptable salt thereof, and a solubilizing agent; methods of making the same; and methods of using the same.
    Type: Application
    Filed: July 24, 2018
    Publication date: January 31, 2019
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Gary Conard Visor, Tomoari Kamo, Hiroshi Yamakose
  • Solid forms of a compound modulating kinases
    Patent number: 10189833
    Abstract: Solid forms of the compound, [5-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-(6-trifluoromethyl-pyridin-3-ylmethyl)-amine HCl salt (Compound I) and its free base, active on the receptor protein kinases c-Kit and/or c-Fms and/or Flt3, were prepared and characterized: Also provided are methods of using the solid forms.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: January 29, 2019
    Assignee: Plexxikon Inc.
    Inventors: Prabha N. Ibrahim, Gary Conard Visor
  • SOLID FORMS OF A COMPOUND MODULATING KINASES
    Publication number: 20180030051
    Abstract: Solid forms of the compound, [5-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-(6-trifluoromethyl-pyridin-3-ylmethyl)-amine HCl salt (Compound I) and its free base, active on the receptor protein kinases c-Kit and/or c-Fms and/or Flt3, were prepared and characterized: Also provided are methods of using the solid forms.
    Type: Application
    Filed: October 4, 2017
    Publication date: February 1, 2018
    Inventors: Prabha N. Ibrahim, Gary Conard Visor
  • Solid forms of a compound modulating kinases
    Patent number: 9802932
    Abstract: Solid forms of the compound, [5-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-(6-trifluoromethyl-pyridin-3-ylmethyl)-amine HCl salt (Compound I) and its free base, active on the receptor protein kinases c-Kit and/or c-Fms and/or Flt3, were prepared and characterized: Also provided are methods of using the solid forms.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: October 31, 2017
    Assignee: Plexxikon Inc.
    Inventors: Prabha N. Ibrahim, Gary Conard Visor
  • SOLID FORMS OF A COMPOUND FOR MODULATING KINASES
    Publication number: 20160340357
    Abstract: Solid forms of Compound I (and its S-enantiomer, Compound II), active on protein kinases, were prepared and characterized: Also provided are methods of using the solid forms.
    Type: Application
    Filed: May 20, 2016
    Publication date: November 24, 2016
    Inventors: Prabha N. Ibrahim, Gary Conard Visor
  • SOLID FORMS OF A COMPOUND MODULATING KINASES
    Publication number: 20160326168
    Abstract: Solid forms of the compound, [5-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-(6-trifluoromethyl-pyridin-3-ylmethyl)-amine HCl salt (Compound I) and its free base, active on the receptor protein kinases c-Kit and/or c-Fms and/or Flt3, were prepared and characterized: Also provided are methods of using the solid forms.
    Type: Application
    Filed: May 5, 2016
    Publication date: November 10, 2016
    Inventors: Prabha N. Ibrahim, Gary Conard Visor
  • Solid forms of a pharmaceutically active substance
    Patent number: 8865735
    Abstract: The present invention provides solid forms of the compound of formula 1 and pharmaceutical uses thereof.
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: October 21, 2014
    Assignees: Hoffman-La Roche Inc., Plexxikon Inc.
    Inventors: Prabha N. Ibrahim, Gary Conard Visor, Shan-Ming Kuang, Baoshu Zhao, Ralph Diodone, Karsten Fähnrich, Urs Schwitter
  • Solid forms of a pharmaceutically active substance
    Patent number: 8748455
    Abstract: The present invention provides solid forms of the compound of formula 1 and pharmaceutical uses thereof.
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: June 10, 2014
    Assignees: Plexxikon Inc., Hoffman-La Roche Inc.
    Inventors: Prabha N. Ibrahim, Gary Conard Visor, Shan-Ming Kuang, Baoshu Zhao, Ralph Diodone, Karsten Fähnrich, Urs Schwitter