Patents by Inventor Gary D. Bren

Gary D. Bren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF REDUCING TRAIL-INDUCED APOPTOSIS BY TRAIL ISOFORMS
    Publication number: 20120322984
    Abstract: This document provides to methods and materials related to apoptosis. For example, methods and materials for modulating apoptosis are provided. In addition, methods and materials for treating a mammal having an apoptosis-associated condition are provided.
    Type: Application
    Filed: August 22, 2012
    Publication date: December 20, 2012
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Andrew D. Badley, Gary D. Bren, David J. Schnepple
  • METHODS OF REDUCING TRAIL-INDUCED APOPTOSIS BY TRAIL ISOFORMS
    Publication number: 20120035113
    Abstract: This document provides to methods and materials related to apoptosis. For example, methods and materials for modulating apoptosis are provided. In addition, methods and materials for treating a mammal having an apoptosis-associated condition are provided.
    Type: Application
    Filed: July 25, 2011
    Publication date: February 9, 2012
    Inventors: Andrew D. Badley, Gary D. Bren, David J. Schnepple
  • Methods of reducing trail-induced apoptosis by trail isoforms
    Patent number: 8008261
    Abstract: This document provides to methods and materials related to apoptosis. For example, methods and materials for modulating apoptosis are provided. In addition, methods and materials for treating a mammal having an apoptosis-associated condition are provided.
    Type: Grant
    Filed: August 2, 2007
    Date of Patent: August 30, 2011
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Andrew D. Badley, Gary D. Bren, David J. Schnepple
  • METHODS AND MATERIALS RELATED TO TRAIL ISOFORMS
    Publication number: 20100172914
    Abstract: This document provides to methods and materials related to apoptosis. For example, methods and materials for modulating apoptosis are provided. In addition, methods and materials for treating a mammal having an apoptosis-associated condition are provided.
    Type: Application
    Filed: August 2, 2007
    Publication date: July 8, 2010
    Inventors: Andrew D. Badley, Gary D. Bren, David J. Schnepple
  • IMMUNODEFICIENCY VIRUSES
    Publication number: 20100062462
    Abstract: This document relates to methods and materials involved in detecting, monitoring, and prognosing immunodeficiency virus infections. For example, methods and materials for determining whether or not a mammal (e.g., a human) has an immunodeficiency virus infection (e.g., an HIV infection), methods and materials for determining whether or not a mammal with an immunodeficiency virus infection is improving, and methods and materials for determining whether or not a mammal with an immunodeficiency virus infection has an advanced immunodeficiency virus infection are provided.
    Type: Application
    Filed: December 14, 2006
    Publication date: March 11, 2010
    Inventors: Andrew D. Badley, Gary D. Bren, Zilin Nie
  • Tumor-specific genomic instability as a prognostic indicator
    Patent number: 5578450
    Abstract: A method for assessing the level of genomic instability in a malignant tumor is described. The method involves comparison of the structure of one or more interspersed repetitive sequence loci in tumor and corresponding normal tissue samples. Microsatellite repetitive sequences are one useful form of interspersed repetitive sequence that may be employed to characterize the genomic instability associated with some malignant tumors. This assessment provides an additional prognostic indicator for patients having such malignant tumors.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: November 26, 1996
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Steven N. Thibodeau, Gary D. Bren