Patents by Inventor Gary D. Krzyzanowski

Gary D. Krzyzanowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cis di-ahl modified controls for glycated hemoglobin S-A1c derived from healthy blood cells
    Patent number: 8551784
    Abstract: The invention is composition comprising red blood cells in an aqueous suspension medium and one or more cis di-ahls; wherein more than 6 percent by weight of the hemoglobin in the red blood cells is S-Alc glycated hemoglobin. In another embodiment, the invention is a method comprising contacting red blood cells in a suspension medium having a concentration of S-Alc glycated hemoglobin of greater than 6 percent by weight of the hemoglobin in the red blood cells with a sufficient amount of one or more cis di-ahls such that the concentration of S-Alc glycated hemoglobin in resulting composition as measured by high pressure liquid chromatography, immunoassay and boronate affinity methods is consistent.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: October 8, 2013
    Assignee: Streck, Inc.
    Inventors: Kausik Das, Gary D. Krzyzanowski
  • Method of preparing controls for glycated hemoglobin S-A1c derived from healthy blood cells
    Patent number: 8546144
    Abstract: By way of summary, the present invention meets some or all of the above needs by providing in a first aspect a method comprising contacting red blood cells in a suspension medium containing mannose under conditions such that the concentration of S-Alc glycated hemoglobin is increased to greater than about 6 percent by weight of the hemoglobin in the red blood cells. Preferably the suspension medium is an aqueous suspension medium. In preferred embodiments, the method is performed at about ambient temperature, 18° C. to about 23° C.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: October 1, 2013
    Assignee: Streck, Inc.
    Inventors: Kausik Das, Gary D. Krzyzanowski, Joel Lechner, Stephanie Wigginton
  • METHOD OF PREPARING CONTROLS FOR GLYCATED HEMOGLOBIN S-A1C DERIVED FROM HEALTHY BLOOD CELLS
    Publication number: 20120129147
    Abstract: By way of summary, the present invention meets some or all of the above needs by providing in a first aspect a method comprising contacting red blood cells in a suspension medium containing mannose under conditions such that the concentration of S-Alc glycated hemoglobin is increased to greater than about 6 percent by weight of the hemoglobin in the red blood cells. Preferably the suspension medium is an aqueous suspension medium. In preferred embodiments, the method is performed at about ambient temperature, 18° C. to about 23° C.
    Type: Application
    Filed: November 17, 2011
    Publication date: May 24, 2012
    Applicant: STRECK, INC.
    Inventors: Kausik Das, Gary D. Krzyzanowski, Joel Lechner, Stephanie Wigginton
  • CIS DI-AHL MODIFIED CONTROLS FOR GLYCATED HEMOGLOBIN S-A1C DERIVED FROM HEALTHY BLOOD CELLS
    Publication number: 20120122073
    Abstract: The invention is composition comprising red blood cells in an aqueous suspension medium and one or more cis di-ahls; wherein more than 6 percent by weight of the hemoglobin in the red blood cells is S-Alc glycated hemoglobin. In another embodiment, the invention is a method comprising contacting red blood cells in a suspension medium having a concentration of S-Alc glycated hemoglobin of greater than 6 percent by weight of the hemoglobin in the red blood cells with a sufficient amount of one or more cis di-ahls such that the concentration of S-Alc glycated hemoglobin in resulting composition as measured by high pressure liquid chromatography, immunoassay and boronate affinity methods is consistent.
    Type: Application
    Filed: November 17, 2011
    Publication date: May 17, 2012
    Applicant: STRECK, INC.
    Inventors: Kausik Das, Gary D. Krzyzanowski