Patents by Inventor Gary Durack
Gary Durack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8709825Abstract: A nozzle for use in a flow cytometer and a method of orienting particles with a baffle disposed within a nozzle. The baffle may be a baffle plate positioned in a fluid flow path to deflect a fluid stream and to orient particles in a desired orientation as they exit the nozzle.Type: GrantFiled: March 1, 2013Date of Patent: April 29, 2014Assignee: Inguran, LLCInventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
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Patent number: 8709817Abstract: A flow cytometry system and method for sorting a mixture of particles, such as a fluid switching sorting system for sorting selected particles which includes a control having a microprocessor programmed with instructions for implementing a control strategy for controlling the fluid delivery to the system to vary the rate at which fluid is delivered as a function of the purity or yield of a sub-population of particles.Type: GrantFiled: February 7, 2013Date of Patent: April 29, 2014Assignee: Inguran, LLCInventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
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Patent number: 8691584Abstract: A method of analyzing particles in a fluid stream including focusing a generally elliptical beam spot to a width less than the size of the particles. As particles pass through the beam spot electromagnetic radiation from the particles which is then detected and converted into electrical signals indicative of characteristics of the particles. The electrical signals may be digitally sampled to provide digital information which may be analyzed to extract information and to classify the particles.Type: GrantFiled: February 25, 2013Date of Patent: April 8, 2014Assignee: Inguran, LLCInventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
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Patent number: 8664006Abstract: A nozzle system for use in a flow cytometer for analyzing particles in a fluid stream and a method of orienting particles in a flow cytometer. The nozzle system may include a nozzle having a longitudinal axis, an interior surface defining a fluid flow path for orienting particles in the nozzle, and a downstream orifice through which a fluid stream exits. The nozzle system may also include a conduit positioned to introduce a core stream containing particles at a location offset from the longitudinal axis and a baffle downstream of the conduit to deflect the fluid stream. The method may include the steps of causing a sheath fluid to flow through the nozzle, introducing a core fluid stream into the sheath fluid at a location offset to the longitudinal axis of the nozzle, and deflecting the core fluid stream with a baffle.Type: GrantFiled: March 1, 2013Date of Patent: March 4, 2014Assignee: Inguran, LLCInventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
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Patent number: 8637318Abstract: A method for classifying particles according to one or more particle characteristics. The method includes operating multiple flow cytometer units to form separate fluid streams that each contain a mixture of particles and to classify particles in the mixtures by interrogating the streams with beams of electromagnetic radiation. A common processor receives and processes information from the units and sends a control signal in real time to adjust the unit's operation as a function of the information received by the common processor.Type: GrantFiled: February 7, 2013Date of Patent: January 28, 2014Assignee: Inguran, LLCInventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
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Patent number: 8623658Abstract: A method of cryopreserving sperm cells which may include cooling the quantity of sperm cells to a holding temperature, maintaining the sperm cells substantially at the holding temperature for a period, and supercooling the sperm cells by cooling the sperm cells at a first cooling rate to a temperature that approaches a critical temperature zone at which ice crystal formation and changes in osmotic pressure damage sperm cells and then cooling the sperm at a second cooling rate faster than said first cooling rate through said critical temperature zone.Type: GrantFiled: March 1, 2013Date of Patent: January 7, 2014Assignee: Inguran, LLCInventors: Jeffrey A. Graham, Cindy Ludwig, Muhammad Anzar, Kathleen S. Crowley, Bradley Didion, Gary Durack
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Patent number: 8623657Abstract: An apparatus and method for analyzing characteristics of particles in a fluid stream. The particles may be intermittently illuminated at an interrogation location with a pulsed laser. A time-varying signal produced in response to the illumination may be analyzed as a function of a timing signal in order to determine characteristics of the particles in the fluid stream.Type: GrantFiled: February 25, 2013Date of Patent: January 7, 2014Assignee: Inguran, LLCInventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
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Patent number: 8617904Abstract: A method of processing animal sperm cells that includes: collecting sperm cells from a male animal; sorting the sperm cells to obtain a quantity of sperm cells having a desired characteristic, the quantity of sorted sperm cells being contained in a first volume of fluid having a first concentration of sperm cells; and subjecting the sperm cells to concentration steps in which the concentration of the sperm cells is increased to a second concentration greater than the first concentration.Type: GrantFiled: February 25, 2013Date of Patent: December 31, 2013Assignee: Inguran, LLCInventors: Gary Durack, Muhammad Anzar, Cindy Ludwig, Jeffrey A. Graham, Kathleen S. Crowley, Bradley Didion
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Patent number: 8609422Abstract: A droplet interference system for sorting cells and a method for the same. The droplet interference system including a droplet generating system for producing a droplet which hits a fluid stream causing a selected segment of the fluid stream, and the cells contained therein, to be separated from the fluid stream.Type: GrantFiled: February 7, 2013Date of Patent: December 17, 2013Assignee: Inguran, LLCInventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
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Patent number: 8535938Abstract: A system and apparatus for sorting a mixture of stained particles in a fluid flow path, including stained particles. The system can include a pulsed electromagnetic radiation source for exciting fluorescence emissions from the stained particles, a photodetector for detecting the fluorescence emissions from the stained particles, a processor for classifying the stained particles; and a photo-damaging laser for damaging selected particles in the flow path.Type: GrantFiled: March 16, 2012Date of Patent: September 17, 2013Assignee: Inguran, LLCInventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
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Patent number: 8389291Abstract: A system and method for the measurement of multiple fluorescence emissions in a flow cytometry system is disclosed where each excitation light source is modulated with a different frequency. A single detector is used to collect the fluorescent emissions excited by all light sources, and the emissions are segregated using Fourier Transform techniques. Systems and methods for the correction of inter-beam coincidence are also disclosed.Type: GrantFiled: December 19, 2011Date of Patent: March 5, 2013Assignee: Sony Biotechnology Inc.Inventors: Gary Durack, Jeremy Hatcher
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Patent number: 8384045Abstract: A minute particle analyzing device includes: a light source; a first condenser lens for condensing light from the light source to a first end of a multimode optical fiber; a second condenser lens for condensing the light emerging from a second end of the multimode optical fiber to a minute particle; and a detector for detecting light generated from the minute particle by the application of the light from the light source.Type: GrantFiled: July 1, 2010Date of Patent: February 26, 2013Assignee: Sony CorporationInventors: Koji Takasaki, Katsuhiro Seo, Mitsuru Toishi, Shinji Yamada, Atsushi Fukumoto, Gary Durack
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Publication number: 20120244610Abstract: A system and apparatus for sorting a mixture of stained particles in a fluid flow path, including stained particles. The system can include a pulsed electromagnetic radiation source for exciting fluorescence emissions from the stained particles, a photodetector for detecting the fluorescence emissions from the stained particles, a processor for classifying the stained particles; and a photo-damaging laser for damaging selected particles in the flow path.Type: ApplicationFiled: March 16, 2012Publication date: September 27, 2012Applicant: INGURAN, LLCInventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
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Patent number: 8241914Abstract: A method and apparatus for sorting stained particles in a fluid stream, each of the method and apparatus including an epi-illumination optics system with a focusing lens. The optics system being operable to direct a beam of electromagnetic radiation through the focusing lens in a forward direction along a beam axis intersecting particles in the fluid stream at the first location so that the particles pass through the beam, resulting in the fluorescence emissions from the particles being directed along the beam axis in a rearward direction.Type: GrantFiled: May 12, 2011Date of Patent: August 14, 2012Assignee: Inguran LLCInventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
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Patent number: 8206987Abstract: A system and method for sorting a mixture of stained particles in a fluid flow path, including stained particles from two distinguishable groups. The system and method can include an electromagnetic radiation source for exciting fluorescence emissions from the stained particles, a photodetector for detecting the fluorescence emissions from the stained particles, a processor for classifying the stained particles; and a photo-damaging laser for damaging selected particles in the flow path.Type: GrantFiled: May 12, 2011Date of Patent: June 26, 2012Assignee: Inguran LLCInventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
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Patent number: 8206988Abstract: A flow cytometry nozzle and method for orienting sperm cells in a fluid flow path including an interior surface of a nozzle. The interior surface of the nozzle having a first, a second and a third axially tapered region for progressively accelerating the speed of a fluid stream in a downstream direction toward a nozzle exit. At least two of the regions having generally elliptical cross sectional shapes oriented in different directions for applying torsional forces to a fluid stream passing there through, tending to bring sperm cells in the stream into a desired orientation.Type: GrantFiled: May 12, 2011Date of Patent: June 26, 2012Assignee: Inguran LLCInventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
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Patent number: 8198093Abstract: A method of sorting stained particles in a flow cytometer by generating a mathematical model based upon extracted features of waveform pulses produced in response to the stained particles. Waveform pulses can then be analyzed to determine the probability the stained particles belong in either a first or a second population and a decision boundary can be established. Sorting decisions can be made based upon the extracted features of the waveform pulses relative to the decision boundary in combination with other desirability factors for particles or droplets containing the particles.Type: GrantFiled: July 12, 2011Date of Patent: June 12, 2012Assignee: Inguran LLCInventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
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Patent number: 8198092Abstract: A system and method for sorting a mixture of stained particles including a digital signal processor for analyzing and classifying the digital information generated from the particles and providing a sorting signal to a sorting system as a function of the analyzed and classified digital information.Type: GrantFiled: May 17, 2011Date of Patent: June 12, 2012Assignee: Inguran, LLCInventors: Gary Durack, Jeffrey D. Wallace, Gary P. Vandre, Lon A. Westfall, Jeremy T. Hatcher, Niraj V. Nayak
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Publication number: 20120091366Abstract: A system and method for the measurement of multiple fluorescence emissions in a flow cytometry system is disclosed where each excitation light source is modulated with a different frequency. A single detector is used to collect the fluorescent emissions excited by all light sources, and the emissions are segregated using Fourier Transform techniques. Systems and methods for the correction of inter-beam coincidence are also disclosed.Type: ApplicationFiled: December 19, 2011Publication date: April 19, 2012Inventors: Gary Durack, Jeremy Hatcher
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Patent number: 8101426Abstract: A system and method for the measurement of multiple fluorescence emissions in a flow cytometry system is disclosed where each excitation light source is modulated with a different frequency. A single detector is used to collect the fluorescent emissions excited by all light sources, and the emissions are segregated using Fourier Transform techniques. Systems and methods for the correction of inter-beam coincidence are also disclosed.Type: GrantFiled: April 23, 2007Date of Patent: January 24, 2012Assignee: iCyt Mission Technology, Inc.Inventors: Gary Durack, Jeremy Hatcher