Patents by Inventor Gary E. Keck

Gary E. Keck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BRYOSTATIN ANALOGS AND USE THEREOF AS ANTIVIRAL AGENTS
    Publication number: 20170239212
    Abstract: Described herein are tricyclic macrolactones. The macrolactones have a high binding affinity for PKC. The compounds described herein can be used in a number of therapeutic applications including the treatment or prevention of viral infection. Also described herein are methods for producing macrolactones. The methods permit the high-yield synthesis of macrolactones in a low number of steps and with a high degree of substitution and specificity.
    Type: Application
    Filed: August 10, 2015
    Publication date: August 24, 2017
    Inventors: Gary E. KECK, Matthew B. KRAFT, Anh P. TRUONG, Carina C. SANCHEZ, Wei LI, Jonathan A. COVEL, Dennie WELCH, Yam POUDEL, Mark E. PETERSEN
  • Bryostatin analogues and methods of making and using thereof
    Patent number: 9096550
    Abstract: Described herein are tricyclic macrolactones. The macrolactones have a high binding affinity for PKC. The compounds described herein can be used in a number of therapeutic applications including cancer and Alzheimer's prevention and treatment. The compounds described herein can also treat memory loss. Also described herein are methods for producing macrolactones. The methods permit the high-yield synthesis of macrolactones in fewer steps and with a higher degree of substitution and specificity.
    Type: Grant
    Filed: October 14, 2010
    Date of Patent: August 4, 2015
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Gary E Keck, Matthew B Kraft, Anh P Truong, Carina C Sanchez, Wei Li, Jonathan A Covel, Dennie Welch, Yam Poudel
  • BRYOSTATIN ANALOGUES AND METHODS OF MAKING AND USING THEREOF
    Publication number: 20110269713
    Abstract: Described herein are tricyclic macrolactones. The macrolactones have a high binding affinity for PKC. The compounds described herein can be used in a number of therapeutic applications including cancer and Alzheimer's prevention and treatment. The compounds described herein can also treat memory loss. Also described herein are methods for producing macrolactones. The methods permit the high-yield synthesis of macrolactones in fewer steps and with a higher degree of substitution and specificity.
    Type: Application
    Filed: October 14, 2010
    Publication date: November 3, 2011
    Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Gary E. Keck, Matthew B. Kraft, Anh P. Truong, Carina C. Sanchez, Wei Li, Jonathan A. Covel, Dennie Welch, Yam Poudel