Abstract: A monoclonal antibody, or antigen-binding portion thereof is provided that specifically binds to a region on a mammalian IL-31 protein involved with interaction of the IL-31 protein with its co-receptor, wherein the binding of said antibody to said region is impacted by mutations in a 15H05 epitope binding region selected from: a region between about amino acid residues 124 and 135 of a feline IL-31 sequence represented by SEQ ID NO: 157 (Feline_IL31_wildtype); a region between about amino acid residues 124 and 135 of a canine IL-31 sequence represented by SEQ ID NO: 155 (Canine_IL31); and a region between about amino acid residues 118 and 129 of an equine IL-31 sequence represented by SEQ ID NO: 165 (Equine_IL31). Such antibodies can be in the form of veterinary compositions useful for treating IL-31-mediated disorders in cats, dogs, or horses.

Abstract: An edge device is dynamically reconfigured to block undesired traffic using control information that originates in a core network. The control information is delivered to the device indirectly and, in particular, by a core appliance (e.g., an intrusion prevention system) setting and returning an HTTP cookie to a requesting client. The edge device is pre-configured to respond to HTTP cookies that have (or that are) control information. When the receiving client later returns that cookie to the edge device to obtain subsequent service, the control information that originated at the core is used by the device to deny that service. This indirect method of communicating the control information (from the core to the requesting client and then back to the device) enables the device to be reconfigured dynamically as needed to address network exploits or other threats.

Abstract: A cell-based assay for assessing the functional activity of a canine or feline IL-31 inhibitor candidate is provided. Such a canine or feline IL-31 inhibitor candidate can be an isolated antibody that specifically binds to at least one of canine Interleukin-31 (IL-31) or feline IL-31. Such antibodies can be in the form of diagnostic and/or veterinary compositions useful for treating a pruritic and/or allergic condition in dogs or cats.

Abstract: An electric motor comprising: a stator assembly; a rotor assembly; and a support body. The stator assembly comprises a plurality of stator elements, and the rotor assembly comprises a shaft to which is mounted at least a first and a second bearing mounted either side of a permanent magnet. The support body comprises an elongate central part, and first and second bearing seats positioned axially at opposite ends of the elongated central part to each other, and the elongate central part defines a plurality of openings each configured to receive one of the plurality of stator elements.

Abstract: A low constant pressure injection molding machine forms molded parts by injecting molten thermoplastic material into a mold cavity at low substantially constant pressures of 6,000 psi and less. As a result, the low constant pressure injection molding machine includes a mold formed of easily machineable material that is less costly and faster to manufacture than typical injection molds.

Abstract: A low constant pressure injection molding machine forms molded parts by injecting molten thermoplastic material into a mold cavity at low constant pressures of 6,000 psi and lower. As a result, the low constant pressure injection molding machine includes a mold formed of easily machineable material that is less costly and faster to manufacture than typical injection molds.

Abstract: A human transportation device in the form of a variable length skateboard. The variable length skateboard provides a short embodiment allowing the rider greater handling and stopping ability and a long embodiment providing the rider with increased speed ability. The long and short embodiments can quickly and easily be transitioned between at any time or place by the insertion or extraction of at least one removable center deck section. The deck sections are coupled using thumb screw type fasteners and coupler plates thereby removing a need for tools to make the conversion between embodiments. The variable length skateboard provides its owner with multiple embodiments without having to purchase multiple skateboards.

Abstract: Disclosed herein is a method of injection molding at low, substantially constant melt pressures. Embodiments of the disclosed method now make possible a method of injection molding that is more energy—and cost—effective than conventional high-velocity injection molding processes. Embodiments of the disclosed method surprisingly allow for the filling of a mold cavity at low melt pressure without undesirable premature hardening of the thermoplastic material in the mold cavity and without the need for maintaining a constant temperature or heated mold cavity. Heretofore, it would not have been expected that a constant pressure method could be performed at low pressure without such premature hardening of the thermoplastic material when using an unheated mold cavity or cooled mold cavity.

Abstract: An edge device is dynamically reconfigured to block undesired traffic using control information that originates in a core network. The control information is delivered to the device indirectly and, in particular, by a core appliance (e.g., an intrusion prevention system) setting and returning an HTTP cookie to a requesting client. The edge device is pre-configured to respond to HTTP cookies that have (or that are) control information. When the receiving client later returns that cookie to the edge device to obtain subsequent service, the control information that originated at the core is used by the device to deny that service. This indirect method of communicating the control information (from the core to the requesting client and then back to the device) enables the device to be reconfigured dynamically as needed to address network exploits or other threats.

Abstract: The present invention provides a new apparatus/system for determining fertility of mammalian sperm based on a specific sperm-binding test that mimics sperm binding to an egg. The inventive apparatus/system comprises surface-modified beads with a compound or conjugates containing a carbohydrate sequence associated with the mammalian zona-pellucida (ZP) glycoproteins.

Abstract: The present invention is directed to process cheese type products prepared with calcium-reduced ingredients but without emulsifying salts and methods of producing such process cheese type products without emulsifying salts. The process cheeses of the present invention are advantageously resistant to separation during heating and retain desirable organoleptic properties, such as texture, without using emulsifying salts. The process cheeses of the present invention are also lower in sodium than conventional produces cheese products.

Abstract: Process for producing a thermoplastic polymer foam article includes preparing an expandable polymeric formulation comprising a thermoplastic polymer and a blowing agent blend, forming the formulation into an expandable bead, and expanding the expandable bead to form a thermoplastic polymer foam article. The blowing agent blend includes methyl formate, hydrocarbon, and either carbon dioxide or 1,1,1,2-tetrafluoroethane (HFC-134a). The blowing agent blend has a higher effective volatility than that of methyl formate alone. A thermoplastic polymer foam article prepared by a process is also provided.

Abstract: A chewy and intermediate moisture bar is provided that uses a dairy-based binder generally without the need to employ gums, humectants, and sugar syrups as a binder to achieve the moist and chewy texture. In one aspect, the bar includes a dry base uniformly blended with a dairy-based binder that uses high levels of dairy proteins as the main binding component. A method of forming the chewy and intermediate moisture bar is also provided that may use a lay or delay period to allow moisture equilibration or migration from the binder to the dry base.

Abstract: A chewy and intermediate moisture bar is provided that uses a dairy-based binder generally without the need to employ gums, humectants, and sugar syrups as a binder to achieve the moist and chewy texture. In one aspect, the bar includes a dry base uniformly blended with a dairy-based binder that uses high levels of dairy proteins as the main binding component. A method of forming the chewy and intermediate moisture bar is also provided that may use a lay or delay period to allow moisture equilibration or migration from the binder to the dry base.

Abstract: The present invention is directed to process cheese type products prepared with calcium-reduced ingredients but without emulsifying salts and methods of producing such process cheese type products without emulsifying salts. The process cheeses of the present invention are advantageously resistant to separation during heating and retain desirable organoleptic properties, such as texture, without using emulsifying salts. The process cheeses of the present invention are also lower in sodium than conventional produces cheese products.

Abstract: A melt pressure regulating mechanism for an injection molding apparatus having a melt holder for pressurizing molten plastic prior to injection into a mold, the molten plastic having a melt pressure, and an injection element for advancing the molten plastic from the melt holder through a nozzle and into the mold, the melt pressure regulating mechanism comprising a pressure regulating device, comprising at least one of a fluid pressure regulating valve and a pressure relief valve.

Abstract: A dairy-based food component is provided that includes high levels of lactose in moisture, but still retains a smooth and creamy consistency. The compositions and methods provide for higher levels of lactose in moisture phase than previously found possible and still retain low crystal sizes in a finished product to maintain a smooth and creamy texture.

Abstract: The present invention is directed to process cheese type products prepared with calcium-reduced ingredients but without emulsifying salts and methods of producing such process cheese type products without emulsifying salts. The process cheeses of the present invention are advantageously resistant to separation during heating and retain desirable organoleptic properties, such as texture, without using emulsifying salts. The process cheeses of the present invention are also lower in sodium than conventional produces cheese products.

Abstract: Methods of imparting resistance to mold to a food product during extended storage at refrigerated temperatures by topically applying a live yeast and fermented aqueous sugar and ethanol solution to a surface of the food product are provided. The live yeast and fermented aqueous sugar and ethanol solution contains about 1% to about 5% live yeast, about 5% to about 40% sugar, and about 5% to about 20% ethanol and is applied in an amount of about 0.5 to about 2 ml per about 80 to about 100 grams of food product. The live yeast converts ethanol into acetaldehyde at a rate which imparts mold resistance to the food product for up to 6 months at refrigerated temperatures.

Abstract: Disclosed herein is a polymer blend comprising a first polycarbonate comprising a first structural unit derived from a 2-aryl-3,3-bis(4-hydroxyaryl)phthalimidine and a second structural unit derived from a dihydroxy aromatic compound, wherein the second structural unit is not identical to the first structural unit, and a second polycarbonate comprising a structural unit derived from a dihydroxy aromatic compound, wherein the polymer blend has a glass transition temperature of 155 to 200° C.; and wherein a test auricle having a thickness of 3.2 mm and molded from the blend has a haze of less than or equal to 3.0 measured in accordance with ASTM D1003-00. A method of making the polymer blend, and articles prepared from the blend, are also disclosed.