Patents by Inventor Gary Gellerman

Gary Gellerman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conformationally constrained backbone cyclized somatostatin analogs
    Patent number: 6355613
    Abstract: Novel peptides which are conformationally constrained backbone cyclized somatostatin analogs. Methods for synthesizing the somatostatin analogs and for producing libraries of the somatostatin analogs are also disclosed. Furthermore, pharmaceutical compositions comprising somatostatin analogs, and methods of using such compositions are disclosed.
    Type: Grant
    Filed: December 2, 1998
    Date of Patent: March 12, 2002
    Assignee: Peptor Limited
    Inventors: Vered Hornik, Gary Gellerman, Mich El M. Afargan
  • Conformationally constrained backbone cyclized somatostatin analogs
    Patent number: 6051554
    Abstract: Novel peptides which are conformationally constrained backbone cyclized somatostatin analogs. Methods for synthesizing the somatostatin analogs and for producing libraries of the somatostatin analogs are also disclosed. Furthermore, pharmaceutical compositions comprising somatostatin analogs, and methods of using such compositions are disclosed.
    Type: Grant
    Filed: June 19, 1998
    Date of Patent: April 18, 2000
    Assignee: Peptor Limited
    Inventors: Vered Hornik, Gary Gellerman, Mich El M Afargan
  • Comformationally constrained backbone cyclized somatostatin analogs
    Patent number: 5770687
    Abstract: Novel peptide analogs are disclosed. The novel peptides are conformationally constrained backbone cyclized somatostatin analogs. Methods for synthesizing the somatostatin analogs and for producing libraries of the somatostatin analogs are also disclosed. Furthermore, pharmaceutical compositions comprising somatostatin analogs, and methods of using such compositions in the treatment of endocrine disorders, neoplasms and metabolic disorders are also disclosed.
    Type: Grant
    Filed: July 31, 1996
    Date of Patent: June 23, 1998
    Assignees: Peptor Limited, Yissim Research Development Co. of Hebrew University of Jerusalem
    Inventors: Vered Hornik, Alon Seri-Levy, Gary Gellerman, Chaim Gilon
  • Biological applications of alkaloids derived from the tunicate Eudistoma sp.
    Patent number: 5432172
    Abstract: Biological applications of synthetic and natural alkaloids derived from the tunicate Eudistoma sp. are disclosed. A method regulating cell growth includes contacting one or more cells with an effective concentration of a compound for regulating cell growth. These compounds include: Segoline A, Segoline B, Isosegoline A, Norosegoline, Debromoshermilamine, Eilatin, 4-methylpyrido[2,3,4-kl]acridine, pyrido[2,3,4-kl]acridine, 1-acetyl-2,6-dimethylpyrido[2,3,4-kl]acridine, and derivatives and combinations of these compounds. An effective concentration range for using these compounds can range from approximately 0.1 .mu.M to 100 .mu.M. The effective concentration range for Eilatin, the most potent of these compounds is from 0.01 .mu.M to 0.99 .mu.M, and the effective concentration range for the other compounds of the present invention is from about 1.0 .mu.M to 100 .mu.M.
    Type: Grant
    Filed: March 9, 1993
    Date of Patent: July 11, 1995
    Assignee: The Research Foundation of State University of New York
    Inventors: Ilan Spector, Nava R. Shochet, Yoel Kashman, Amira Rudi, Gary Gellerman