Abstract: This disclosure relates to a film guide for use with a film loading box on an automatic sequential x-ray machine. Such automatic sequential x-ray machines are rapid changing film devices used for transporting and exposing x-ray film in rapid sequence for special medical procedures. The film guide of this invention is specially adapted to be secured in a film loading box in such a way so as to provide support for x-ray film which is half the size of that normally used in the film loading boxes of such automatic sequential x-ray machines. Since only half the amount of x-ray film and considerably less x-ray film developing solutions are used when the film guide of this invention is installed, rather dramatic and substantial cost savings are possible for hospitals and x-ray laboratories.