Abstract: Scrub resistant inks and methods and apparatus for fabrication and use thereof are provided. Scrub-resistant ink compositions may include a dye for marking skin; and a solvent dissolving a marking effective amount of the dye, wherein the solvent comprises about 0.1 to about 90 percent of a polar aprotic solvent. Apparatus for marking patients may include an ink reservoir; an ink dispenser having a fluid connection to the ink reservoir to dispense the ink at a desired rate to mark a patient; and a scrub resistant ink disposed in the ink reservoir. Methods for forming scrub-resistant ink compositions may include providing a marking effective amount of a dye suitable for use in marking skin; and mixing the dye with a first solvent comprising 0.1% to 90% of a polar aprotic solvent. Methods of marking patients may include applying an ink as recited above to a body part of the patient.

Abstract: Scrub resistant inks and methods and apparatus for fabrication and use thereof are provided. Scrub-resistant ink compositions may include a dye for marking skin; and a solvent dissolving a marking effective amount of the dye, wherein the solvent comprises about 0.1 to about 90 percent of a polar aprotic solvent. Apparatus for marking patients may include an ink reservoir; an ink dispenser having a fluid connection to the ink reservoir to dispense the ink at a desired rate to mark a patient; and a scrub resistant ink disposed in the ink reservoir. Methods for forming scrub-resistant ink compositions may include providing a marking effective amount of a dye suitable for use in marking skin; and mixing the dye with a first solvent comprising 0.1% to 90% of a polar aprotic solvent. Methods of marking patients may include applying an ink as recited above to a body part of the patient.

Abstract: Scrub resistant inks and methods and apparatus for fabrication and use thereof are provided. Scrub-resistant ink compositions may include a dye for marking skin; and a solvent dissolving a marking effective amount of the dye, wherein the solvent comprises about 0.1 to about 90 percent of a polar aprotic solvent. Apparatus for marking patients may include an ink reservoir; an ink dispenser having a fluid connection to the ink reservoir to dispense the ink at a desired rate to mark a patient; and a scrub resistant ink disposed in the ink reservoir. Methods for forming scrub-resistant ink compositions may include providing a marking effective amount of a dye suitable for use in marking skin; and mixing the dye with a first solvent comprising 0.1% to 90% of a polar aprotic solvent. Methods of marking patients may include applying an ink as recited above to a body part of the patient.

Abstract: Scrub resistant inks and methods and apparatus for fabrication and use thereof are provided. Scrub-resistant ink compositions may include a dye for marking skin; and a solvent dissolving a marking effective amount of the dye, wherein the solvent comprises about 0.1 to about 90 percent of a polar aprotic solvent. Apparatus for marking patients may include an ink reservoir; an ink dispenser having a fluid connection to the ink reservoir to dispense the ink at a desired rate to mark a patient; and a scrub resistant ink disposed in the ink reservoir. Methods for forming scrub-resistant ink compositions may include providing a marking effective amount of a dye suitable for use in marking skin; and mixing the dye with a first solvent comprising 0.1% to 90% of a polar aprotic solvent. Methods of marking patients may include applying an ink as recited above to a body part of the patient.

Abstract: Methods and apparatus for inking a surgical instrument are provided herein. In some embodiments, and apparatus for inking a surgical instrument includes: an inking capsule, comprising a base and a vertical wall extending from the base to define a cavity, the inking capsule having a first opening opposite the base; an ink reservoir disposed within the cavity, the ink reservoir having ink disposed therein and comprising a second opening proximate a top portion of the ink reservoir, and a penetrable seal covering the second opening to seal the ink in the ink reservoir when the seal is in an unbroken state.

Abstract: Embodiments of surgical markers for marking internal and external tissues are provided herein. In some embodiments, a surgical marking device for marking tissue may include a body including an at least partially hollow interior, a first end and a second end; a tip coupled to the body at the second end; and a plunger movably coupled to the body at the first end and configured to control a pressure within the at least partially hollow interior of the body via movement of the plunger relative to the body, wherein the pressure control may control a flow of ink outward of the body via the tip during use. Alternatively, in some embodiments, a squeezable bulb may be provided in place of the plunger, the squeezable bulb having an interior volume fluidly coupled to the body, wherein a pressure within the body may be controlled via the squeezable bulb.

Abstract: Embodiments of surgical markers for marking internal and external tissues are provided herein. In some embodiments, a surgical marking device for marking tissue may include a body including an at least partially hollow interior, a first end and a second end; a tip coupled to the body at the second end; and a plunger movably coupled to the body at the first end and configured to control a pressure within the at least partially hollow interior of the body via movement of the plunger relative to the body, wherein the pressure control may control a flow of ink outward of the body via the tip during use. Alternatively, in some embodiments, a squeezable bulb may be provided in place of the plunger, the squeezable bulb having an interior volume fluidly coupled to the body, wherein a pressure within the body may be controlled via the squeezable bulb.

Abstract: Embodiments of surgical markers for marking internal and external tissues are provided herein. In some embodiments, a surgical marking device for marking tissue may include a body including an at least partially hollow interior, a first end and a second end; a tip coupled to the body at the second end; and a plunger movably coupled to the body at the first end and configured to control a pressure within the at least partially hollow interior of the body via movement of the plunger relative to the body, wherein the pressure control may control a flow of ink outward of the body via the tip during use. Alternatively, in some embodiments, a squeezable bulb may be provided in place of the plunger, the squeezable bulb having an interior volume fluidly coupled to the body, wherein a pressure within the body may be controlled via the squeezable bulb.

Abstract: Provided, amongst other things, are dyes of formula II: wherein R1, R2, R3 and R4 are independently H or alkyl, so long as one or more is alkyl, and salts of the compound of formula II. Methods of making, inks, surgical markers and methods of marking tissue and the like are further provided.

Abstract: Scrub resistant inks and methods and apparatus for fabrication and use thereof are provided. Scrub-resistant ink compositions may include a dye for marking skin; and a solvent dissolving a marking effective amount of the dye, wherein the solvent comprises about 0.1 to about 90 percent of a polar aprotic solvent. Apparatus for marking patients may include an ink reservoir; an ink dispenser having a fluid connection to the ink reservoir to dispense the ink at a desired rate to mark a patient; and a scrub resistant ink disposed in the ink reservoir. Methods for forming scrub-resistant ink compositions may include providing a marking effective amount of a dye suitable for use in marking skin; and mixing the dye with a first solvent comprising 0.1% to 90% of a polar aprotic solvent. Methods of marking patients may include applying an ink as recited above to a body part of the patient.

Abstract: Embodiments of surgical markers for marking internal and external tissues are provided herein. In some embodiments, a surgical marking device for marking tissue may include a body including an at least partially hollow interior, a first end and a second end; a tip coupled to the body at the second end; and a plunger movably coupled to the body at the first end and configured to control a pressure within the at least partially hollow interior of the body via movement of the plunger relative to the body, wherein the pressure control may control a flow of ink outward of the body via the tip during use. Alternatively, in some embodiments, a squeezable bulb may be provided in place of the plunger, the squeezable bulb having an interior volume fluidly coupled to the body, wherein a pressure within the body may be controlled via the squeezable bulb.