Patents by Inventor Gary Kruh

Gary Kruh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MRP-related ABC transporter encoding nucleic acids and methods of use thereof
    Patent number: 7312026
    Abstract: Novel human MOAT genes and their encoded proteins are provided herein. The MRP-related ABC transporters encoded by the disclosed nucleic acid sequences play a pivotal role in the efflux of pharmacologically beneficial reagents from tumor cells. MOAT genes and their encoded proteins provide valuable therapeutic targets for the design of anti-cancer agents which inhibit the aberrant growth of malignant cells.
    Type: Grant
    Filed: July 12, 2004
    Date of Patent: December 25, 2007
    Assignee: Fox Chase Cancer Center
    Inventors: Gary Kruh, Kun Lee, Martin Belinsky, Lisa Bain
  • MRP-related ABC transporter encoding nucleic acids and methods of use thereof
    Publication number: 20050063968
    Abstract: Novel human MOAT genes and their encoded proteins are provided herein. The MRP-related ABC transporters encoded by the disclosed nucleic acid sequences play a pivotal role in the efflux of pharmacologically beneficial reagents from tumor cells. MOAT genes and their encoded proteins provide valuable therapeutic targets for the design of anti-cancer agents which inhibit the aberrant growth of malignant cells.
    Type: Application
    Filed: July 12, 2004
    Publication date: March 24, 2005
    Inventors: Gary Kruh, Kun Lee, Martin Belinsky, Lisa Bain
  • MPR-related ABC transporter encoding nucleic acids and methods of use thereof
    Patent number: 6803184
    Abstract: Novel human MOAT genes and their encoded proteins are provided herein. The MRP-related ABC transporters encoded by the disclosed nucleic acid sequences play a pivotal role in the efflux of pharmacologically beneficial reagents from tumor cells. MOAT genes and their encoded protein provide valuable therapeutic targets for the design of anti-cancer agents which inhibit the aberrant growth of malignant cells.
    Type: Grant
    Filed: September 27, 2000
    Date of Patent: October 12, 2004
    Assignee: Fox Chase Cancer Center
    Inventors: Gary Kruh, Kun Lee