Patents by Inventor Gary L. Andersen
Gary L. Andersen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10961593Abstract: Herein are described 1058 different bacterial taxa that were unique to either human, grazing mammal, or bird fecal wastes. These identified taxa can serve as specific identifier taxa for these sources in environmental waters. Two field tests in marine waters demonstrate the capacity of phylogenetic microarray analysis to track multiple sources with one test.Type: GrantFiled: July 6, 2017Date of Patent: March 30, 2021Assignee: The Regents of the University of CaliforniaInventors: Gary L. Andersen, Eric A. Dubinsky
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Publication number: 20180223339Abstract: The present invention discloses methods and systems for designing and using organism-specific and/or operational taxon unit (OTU)-specific probes. The methods and systems allow for detecting, identifying and quantitating a plurality of biomolecules or microorganisms in a sample based on the hybridization or binding of target molecules in the sample with the probes. Some embodiments provide methods of selecting an oligonucleotide probe specific for a node on a clustering tree. Other embodiments provide methods of selecting organism-specific or OTU-specific oligonucleotide probes for use in accurately detecting a plurality of organisms in a sample with high confidence. Some embodiments provide methods and systems to detect the presence of a rare OTU in a sample.Type: ApplicationFiled: March 2, 2018Publication date: August 9, 2018Inventors: Gary L. Andersen, Todd Z. DeSantis, Eoin Brodie
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Publication number: 20170335374Abstract: Herein are described 1058 different bacterial taxa that were unique to either human, grazing mammal, or bird fecal wastes. These identified taxa can serve as specific identifier taxa for these sources in environmental waters. Two field tests in marine waters demonstrate the capacity of phylogenetic microarray analysis to track multiple sources with one test.Type: ApplicationFiled: July 6, 2017Publication date: November 23, 2017Inventors: Gary L. Andersen, Eric A. Dubinsky
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Patent number: 9725770Abstract: Herein are described 1058 different bacterial taxa that were unique to either human, grazing mammal, or bird fecal wastes. These identified taxa can serve as specific identifier taxa for these sources in environmental waters. Two field tests in marine waters demonstrate the capacity of phylogenetic microarray analysis to track multiple sources with one test.Type: GrantFiled: March 6, 2013Date of Patent: August 8, 2017Assignee: The Regents of the University of CaliforniaInventors: Gary L. Andersen, Eric A. Dubinsky
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Publication number: 20150337363Abstract: The present embodiments relate to an array system for detecting and identifying biomolecules and organisms. More specifically, the present embodiments relate to an array system comprising a microarray configured to simultaneously detect a plurality of organisms in a sample at a high confidence level.Type: ApplicationFiled: August 6, 2015Publication date: November 26, 2015Inventors: Gary L. Andersen, Todd Z. DeSantis
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Patent number: 8906610Abstract: Herein is described methods for a high-sensitivity means to measure the incorporation of stable isotope labeled substrates into RNA following stable isotope probing experiments (SIP). RNA is hybridized to a set of probes such as phylogenetic microarrays and isotope incorporation is quantified such as by secondary ion mass spectrometer imaging (NanoSIMS).Type: GrantFiled: February 8, 2011Date of Patent: December 9, 2014Assignee: The Regents of the University of CaliforniaInventors: Eoin L. Brodie, Todd Z. DeSantis, Ulas Karaoz, Gary L. Andersen
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Publication number: 20140200149Abstract: Herein are described 1058 different bacterial taxa that were unique to either human, grazing mammal, or bird fecal wastes. These identified taxa can serve as specific identifier taxa for these sources in environmental waters. Two field tests in marine waters demonstrate the capacity of phylogenetic microarray analysis to track multiple sources with one test.Type: ApplicationFiled: March 6, 2013Publication date: July 17, 2014Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Gary L. Andersen, Eric A. Dubinsky
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Patent number: 8771940Abstract: The present embodiments relate to an array system for detecting and identifying biomolecules and organisms. More specifically, the present embodiments relate to an array system comprising a microarray configured to simultaneously detect a plurality of organisms in a sample at a high confidence level.Type: GrantFiled: May 28, 2009Date of Patent: July 8, 2014Assignee: The Regents of the University of CaliforniaInventors: Gary L. Andersen, Todd D. DeSantis
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Patent number: 8697388Abstract: Compositions and methods are provided for detection of certain heavy metals using bacterial whole cell biosensors.Type: GrantFiled: February 6, 2008Date of Patent: April 15, 2014Assignee: U.S. Department of EnergyInventors: Nathan J. Hillson, Lucille Shapiro, Ping Hu, Gary L. Andersen
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Publication number: 20120165215Abstract: The present invention discloses methods and systems for designing and using organism-specific and/or operational taxon unit (OTU)-specific probes. The methods and systems allow for detecting, identifying and quantitating a plurality of biomolecules or microrganisms in a sample based on the hybridization or binding of target molecules in the sample with the probes. Some embodiments provide methods of selecting an oligonucleotide probe specific for a node on a clustering tree. Other embodiments provide methods of selecting organism-specific or OTU-specific oligonucleotide probes for use in accurately detecting a plurality of organisms in a sample with high confidence. Some embodiments provide methods and systems to detect the presence of a rare OTU in a sample.Type: ApplicationFiled: June 25, 2010Publication date: June 28, 2012Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Gary L. Andersen, Todd Z. Desantis, Eoin Brodie
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Publication number: 20110212850Abstract: Herein is described methods for a high-sensitivity means to measure the incorporation of stable isotope labeled substrates into RNA following stable isotope probing experiments (SIP). RNA is hybridized to a set of probes such as phylogenetic microarrays and isotope incorporation is quantified such as by secondary ion mass spectrometer imaging (NanoSIMS).Type: ApplicationFiled: February 8, 2011Publication date: September 1, 2011Applicant: The Regents of the University of CaliforniaInventors: Eoin L. Brodie, Todd Z. DeSantis, Ulas Karaoz, Gary L. Andersen
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Publication number: 20110117590Abstract: Compositions and methods are provided for detection of certain heavy metals using bacterial whole cell biosensors.Type: ApplicationFiled: February 6, 2008Publication date: May 19, 2011Inventors: Nathan J. Hillson, Lucille Shapiro, Ping Hu, Gary L. Andersen
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Publication number: 20090291858Abstract: The present embodiments relate to an array system for detecting and identifying biomolecules and organisms. More specifically, the present embodiments relate to an array system comprising a microarray configured to simultaneously detect a plurality of organisms in a sample at a high confidence level.Type: ApplicationFiled: May 28, 2009Publication date: November 26, 2009Applicant: The Regents of the University of CaliforniaInventors: Gary L. Andersen, Todd D. DeSantis
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Patent number: 7494773Abstract: Nucleotide sequences specific to Brucella that serves as a marker or signature for identification of this bacterium were identified. In addition, forward and reverse primers and hybridization probes derived from these nucleotide sequences that are used in nucleotide detection methods to detect the presence of the bacterium are disclosed.Type: GrantFiled: July 29, 2003Date of Patent: February 24, 2009Assignee: Lawrence Livermore National Security, LLCInventors: Paula M. McCready, Lyndsay Radnedge, Gary L. Andersen, Linda L. Ott, Thomas R. Slezak, Thomas A. Kuczmarski
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Patent number: 7494778Abstract: Described herein is the identification of nucleotide sequences specific to Francisella tularensis that serves as a marker or signature for identification of this bacterium. In addition, forward and reverse primers and hybridization probes derived from these nucleotide sequences that are used in nucleotide detection methods to detect the presence of the bacterium are disclosed.Type: GrantFiled: December 21, 2006Date of Patent: February 24, 2009Assignee: Lawrence Livermore National Security, LLCInventors: Paula M. McCready, Lyndsay Radnedge, Gary L. Andersen, Linda L. Ott, Thomas R. Slezak, Thomas A. Kuczmarski, Elizabeth A Vitalis
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Patent number: 7494772Abstract: Nucleotide sequences specific to Yersinia pestis that serve as markers or signatures for identification of this bacterium were identified. In addition, forward and reverse primers and hybridization probes derived from these nucleotide sequences that are used in nucleotide detection methods to detect the presence of the bacterium are disclosed.Type: GrantFiled: July 29, 2003Date of Patent: February 24, 2009Assignee: Lawrence Livermore National Security, LLCInventors: Paula M. McCready, Lyndsay Radnedge, Gary L. Andersen, Linda L. Ott, Thomas R. Slezak, Thomas A. Kuczmarski, Vladinir L. Motin
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Patent number: 7442517Abstract: Described herein is the identification of a novel Salmonella enterica serovar Enteritidis locus that serves as a marker for DNA-based identification of this bacterium. In addition, three primer pairs derived from this locus that may be used in a nucleotide detection method to detect the presence of the bacterium are also disclosed herein.Type: GrantFiled: October 16, 2002Date of Patent: October 28, 2008Assignee: Lawrence Livermore National Security, LLCInventors: Peter G. Agron, Gary L. Andersen, Richard L. Walker
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Patent number: 7172868Abstract: Described herein is the identification of nucleotide sequences specific to Francisella tularensis that serves as a marker or signature for identification of this bacterium. In addition, forward and reverse primers and hybridization probes derived from these nucleotide sequences that are used in nucleotide detection methods to detect the presence of the bacterium are disclosed.Type: GrantFiled: July 29, 2003Date of Patent: February 6, 2007Assignee: The Regents of the University of CaliforniaInventors: Paula M. McCready, Lyndsay Radnedge, Gary L. Andersen, Linda L. Ott, Thomas R. Slezak, Thomas A. Kuczmarski, Elizabeth A Vitalis
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Publication number: 20030157696Abstract: Described herein is the identification of a novel Salmonella enterica serovar Enteritidis locus that serves as a marker for DNA-based identification of this bacterium. In addition, three primer pairs derived from this locus that may be used in a nucleotide detection method to detect the presence of the bacterium are also disclosed herein.Type: ApplicationFiled: October 16, 2002Publication date: August 21, 2003Applicant: The Regents of the University of CaliforniaInventors: Peter G. Agron, Gary L. Andersen, Richard L. Walker
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Patent number: 4997557Abstract: A mixing, aerating and decanting unit adapted for floating installation in a liquid treatment basin and operable to provide mixing, aeration, settling and decanting phases in an SBR (sequencing bath reactor) process. The unit comprises a rigid support structure with floats for buoyantly supporting the unit in the basin, a mixing apparatus operable to mix liquid in the basin, an aerating apparatus selectively operable to supply air to the water in the basin, and a decanter apparatus for decanting liquid from the basin.Type: GrantFiled: May 19, 1989Date of Patent: March 5, 1991Assignee: Aqua-Aerobic Systems, Inc.Inventor: Gary L. Andersen