Patents by Inventor Gary L. Haller

Gary L. Haller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10485856
    Abstract: Carbon nanotube (CNT)-based compositions for activating cellular immune responses are provided. The CNTs function as high surface area scaffolds for the attachment of T cell ligands and/or antigens. The CNT compositions function as artificial antigen-presenting cells (aAPCs) or as modular vaccines. The disclosed CNT aAPCs are efficient at activating T cells and may be used to activate T cells ex vivo or in vivo for adoptive or active immunotherapy.
    Type: Grant
    Filed: March 17, 2017
    Date of Patent: November 26, 2019
    Assignee: Yale University
    Inventors: Tarek M. Fahmy, Lisa D. Pfefferle, Gary L. Haller, Tarek R. Fadel
  • Patent number: 9737593
    Abstract: Carbon nanotube (CNT)-based compositions for activating cellular immune responses are provided. The CNTs function as high surface area scaffolds for the attachment of T cell ligands and/or antigens. The CNT compositions function as artificial antigen-presenting cells (aAPCs) or as modular vaccines. The disclosed CNT aAPCs are efficient at activating T cells and may be used to activate T cells ex vivo or in vivo for adoptive or active immunotherapy.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: August 22, 2017
    Assignee: Yale University
    Inventors: Tarek M. Fahmy, Lisa D. Pfefferle, Gary L. Haller
  • Publication number: 20170209570
    Abstract: Carbon nanotube (CNT)-based compositions for activating cellular immune responses are provided. The CNTs function as high surface area scaffolds for the attachment of T cell ligands and/or antigens. The CNT compositions function as artificial antigen-presenting cells (aAPCs) or as modular vaccines. The disclosed CNT aAPCs are efficient at activating T cells and may be used to activate T cells ex vivo or in vivo for adoptive or active immunotherapy.
    Type: Application
    Filed: March 17, 2017
    Publication date: July 27, 2017
    Inventors: Tarek M. Fahmy, Lisa D. Pfefferle, Gary L. Haller
  • Publication number: 20160213761
    Abstract: Carbon nanotube (CNT)-based compositions for activating cellular immune responses are provided. The CNTs function as high surface area scaffolds for the attachment of T cell ligands and/or antigens. The CNT compositions function as artificial antigen-presenting cells (aAPCs) or as modular vaccines. The disclosed CNT aAPCs are efficient at activating T cells and may be used to activate T cells ex vivo or in vivo for adoptive or active immunotherapy.
    Type: Application
    Filed: April 5, 2016
    Publication date: July 28, 2016
    Inventors: Tarek M. Fahmy, Lisa D. Pfefferle, Gary L. Haller
  • Patent number: 8658178
    Abstract: Carbon nanotube (CNT)-based compositions for activating cellular immune responses are provided. The CNTs function as high surface area scaffolds for the attachment of T cell ligands and/or antigens. The CNT compositions function as artificial antigen-presenting cells (aAPCs) or as modular vaccines. The disclosed CNT aAPCs are efficient at activating T cells and may be used to activate T cells ex vivo or in vivo for adoptive or active immunotherapy.
    Type: Grant
    Filed: March 19, 2009
    Date of Patent: February 25, 2014
    Assignee: Yale University
    Inventors: Tarek M. Fahmy, Lisa D. Pfefferle, Gary L. Haller
  • Publication number: 20110014217
    Abstract: Carbon nanotube (CNT)-based compositions for activating cellular immune responses are provided. The CNTs function as high surface area scaffolds for the attachment of T cell ligands and/or antigens. The CNT compositions function as artificial antigen-presenting cells (aAPCs) or as modular vaccines. The disclosed CNT aAPCs are efficient at activating T cells and may be used to activate T cells ex vivo or in vivo for adoptive or active immunotherapy.
    Type: Application
    Filed: March 19, 2009
    Publication date: January 20, 2011
    Inventors: Tarek M. Fahmy, Lisa D. Pfefferle, Gary L. Haller
  • Publication number: 20090325790
    Abstract: A metal-substituted mesoporous oxide framework, such as Co-MCM-41, are disclosed which includes more than one ion species with different reduction kinetics. The reducibility correlates strongly with the pore radius of curvature, with the metal ions incorporated in smaller pores more resistant to complete reduction. The metal-ion substituted oxide framework improves catalytic processes by controlling the size of the catalytic particles forming in the pores. The metal-substituted mesoporous oxide framework can be employed in selective hydrogenation of organic chemicals, in ammonia synthesis, and in automotive catalytic exhaust systems.
    Type: Application
    Filed: June 17, 2005
    Publication date: December 31, 2009
    Applicant: Yale University
    Inventors: Gary L. Haller, Sangyun Lim, Dragos Ciuparu, Yuan Chen, Yanhui Yang, Lisa Pfefferle
  • Patent number: 5733518
    Abstract: The invention comprises a process for selectively oxidizing hydrogen in a mixture with other gaseous materials by contacting the hydrogen containing gas under oxidation conditions with a catalyst comprising a phosphate of a metal wherein the metal is selected from the group consisting of germanium, tin, lead, arsenic, antimony and bismuth.
    Type: Grant
    Filed: July 10, 1996
    Date of Patent: March 31, 1998
    Assignee: Sun Company, Inc. (R&M)
    Inventors: Vincent A. Durante, Daniel E. Resasco, Darrell W. Walker, Gary L. Haller, Eugene L. Coggins
  • Patent number: 5540833
    Abstract: New compositions of matter comprise a metal from the group consisting of platinum, rhodium and palladium, a metal from the first row of Group VIII of the Periodic Table and a nonacidic L-zeolite. A preferred composition is Pt--Ni/KL-zeolite. Such catalysts are prepared by coimpregnation of the zeolite with the metals. Methods of using the catalysts in reforming, aromatization or dehydrogenation are provided.
    Type: Grant
    Filed: January 31, 1994
    Date of Patent: July 30, 1996
    Assignee: Sun Company, Inc. (R&M)
    Inventors: Gustavo Larsen, Gary L. Haller, Daniel E. Resasco, Vincent A. Durante
  • Patent number: 5439859
    Abstract: Alkanes are dehydrogenated by passage through alternating dehydrogenation zones and selective oxidation zone(s), in which latter zone(s) hydrogen produced in the preceding endothermic dehydrogenation reaction is selectively oxidized to generate heat for the succeeding dehydrogenation reaction. New catalyst compositions are prepared comprising reduced and sulfided nickel crystallites on siliceous supports which have been treated with chromium compounds and oxidized to provide surface-anchored chromyl species. Also new catalyst compositions are prepared by sulfiding nickel-containing compositions with carbonaceous sulfur compounds such as dialkylsulfoxides. Another embodiment of the invention is catalyst and dehydrogenation therewith, in which pores having radius of 50 to 200 Angstroms occupy pore volume from 0.30 to 1.50 ml per gram of the support, and pores having radius of 20 to 50 Angstroms occupy pore volume less than 0.1 ml per gram of the support.
    Type: Grant
    Filed: April 27, 1992
    Date of Patent: August 8, 1995
    Assignee: Sun Company, Inc. (R&M)
    Inventors: Vincent A. Durante, Daniel E. Resasco, Darrell W. Walker, Gary L. Haller, Eugene L. Coggins