Abstract: Example access devices, treatment devices, and kits useful in performing treatment under magnetic resonance imaging and related methods are described. An example access device includes an elongate tubular member formed of an MRI compatible material and moveable between a first, unexpanded configuration and a second, expanded configuration. The elongate tubular member has a central lengthwise axis, a proximal end, a distal end, an axial length, and a main body that defines a circumferential wall, a lumen, a proximal opening, a distal opening, and a main body opening. The main body opening is arranged in a spiral relative to the lengthwise axis and extends circumferentially along the circumferential wall. The main body opening extends along the entire axial length of the elongate tubular member from the proximal end to the distal end.

Abstract: Example interventional medical devices useful in performing treatment under magnetic resonance imaging and related methods are described. A method of making a medical device useful in procedures performed under magnetic resonance imaging includes selecting a first material, selecting a second material that is different from the first material, incorporating the second material into a portion of the first material, and forming the first and second materials into a desired structure to form the interventional medical device. The second material can be melted and disposed in a void formed in the first material, and work hardened to increase magnetic susceptibility.

Abstract: Example medical devices for performing treatment under magnetic resonance imaging and related methods are described. An example medical device includes a cannula and a plug. The cannula has a proximal end, a distal end, a first portion, a second portion, and a main body that defines a lumen and a passageway. The first portion extends from the distal end toward the proximal end. The second portion extends from the first portion toward the proximal end. The first portion is formed of first material. The second portion is formed of a second material that is different than the first material. The plug is disposed within the passageway and has a main body that defines a passageway in fluid communication with the lumen defined by the cannula. The plug is formed of a third material that is different than the second material.

Abstract: Example tissue removal devices and kits useful in performing treatment under magnetic resonance imaging and related methods are described. An example tissue removal device includes an elongate member and a tubular member partially disposed over the elongate member. The elongate member has a lengthwise axis and a main body that defines a lumen, a proximal portion, a coil member, and a sharp edge. The coil member extends around a portion of the lengthwise axis in a first direction. The coil member extends from the away from the lengthwise axis and away from the proximal portion. The tubular member has a proximal end, a distal end, and a main body that defines a lumen and a slot. The slot extends from the distal end of the tubular member toward the proximal end of the tubular member. The slot is sized to receive a portion of the coil member.

Abstract: A catheter hub for use with a medical device and a catheter, the hub includes a hub body defining a fluid passageway in communication with a first aperture. Optionally, the hub body defines a second aperture that intersects the first aperture. The hub body attaches to the catheter wherein the fluid passageway and the catheter are aligned for fluid flow therethrough. The first aperture extends from and communicates with the fluid passageway to an exterior surface of the hub body and the first aperture configured to receive the medical device. The second aperture extends from and communicates with the first aperture and the exterior surface. A sealing element is sized for and positioned in either the first or the second apertures. The sealing element is configured to receive the medical device and seal both of the first and the second apertures.

Abstract: A catheter hub for use with a medical device and a catheter, the hub includes a hub body defining a fluid passageway in communication with a first aperture. Optionally, the hub body defines a second aperture that intersects the first aperture. The hub body attaches to the catheter wherein the fluid passageway and the catheter are aligned for fluid flow therethrough. The first aperture extends from and communicates with the fluid passageway to an exterior surface of the hub body and the first aperture configured to receive the medical device. The second aperture extends from and communicates with the first aperture and the exterior surface. A sealing element is sized for and positioned in either the first or the second apertures. The sealing element is configured to receive the medical device and seal both of the first and the second apertures.

Abstract: Methods of treating diverticulosis and medical devices suitable for use in such methods are described herein. In an embodiment, a method of treating diverticulosis in an animal comprises clearing the lumen of the colon of the animal of solid matter, isolating a treatment portion of the colon, applying suction at a point within the lumen of the colon to depressurize the treatment portion, applying a material to the external surface across at least one diverticulum of the diverticula on the colon, and removing the suction. In some embodiments, the material comprises an adhesive. A step of applying a second material across at least one diverticulum of the diverticula on the colon can also be included.

Abstract: An indwelling stent is provided. The stent includes a distal member that extends between a distal end portion and a proximal end portion and defines a lumen therethrough, and a proximal member that extends between a distal end portion and a proximal end portion and defines a lumen therethrough, wherein the distal member and the proximal member collectively define the stent, and wherein the distal and proximal members are discrete components and are telescopingly arranged with the distal end portion of the proximal member extending over an outer surface of the distal member.

Abstract: A method of sealing a trachea is provided that includes inserting a tracheal tube having an inflatable cuff made of a compliant material into a trachea. The method includes inflating the inflatable cuff with a fluid to a first pressure that exceeds a second pressure necessary to create a seal between the inflatable cuff and the tracheal wall. The method includes deflating the inflatable cuff by releasing a first pressure to allow the fluid to flow out of the inflatable cuff without applying vacuum pressure to the fluid while evaluating a rate of change of pressure of the fluid in the inflatable cuff. The method includes identifying a variance in the rate of change of pressure corresponding to a third pressure at which the inflatable cuff separates from the tracheal wall, determining the second pressure by analyzing the third pressure, and reinflating the inflatable cuff to the second pressure.

Abstract: A dilator may include a leading portion that includes a leading end coupled to a leading stem. The dilator may further include a trailing portion that includes a trailing end coupled to a trailing shaft. The dilator may also include a segmented body disposed between the leading end and the trailing end. The segmented body may include a plurality of segments disposed circumferentially around the leading stem. The leading stem may extend through a passageway of the segmented body, an opening of the trailing end and a channel of the trailing shaft. The leading stem and the trailing shaft may be configured to move longitudinally relative to one another to radially outwardly expand the segmented body.

Abstract: An indwelling stent is provided. The stent includes a distal member that extends between a distal end portion and a proximal end portion and defines a lumen therethrough, and a proximal member that extends between a distal end portion and a proximal end portion and defines a lumen therethrough, wherein the distal member and the proximal member collectively define the stent, and wherein the distal and proximal members are discrete components and are telescopingly arranged with the distal end portion of the proximal member extending over an outer surface of the distal member.

Abstract: An indwelling stent is provided. The stent includes a distal member that extends between a distal end portion and a proximal end portion and defines a lumen therethrough, and a proximal member that extends between a distal end portion and a proximal end portion and defines a lumen therethrough, wherein the distal member and the proximal member collectively define the stent, and wherein the distal and proximal members are discrete components and are telescopingly arranged with the distal end portion of the proximal member extending over an outer surface of the distal member.

Abstract: Medical devices and methods are provided. In some aspects, devices useful for applying therapy locally within a body vessel are disclosed, the devices having a stent graft with flared end regions with a catheter providing fluid communication to the outer side of the narrower, intermediate region of the stent graft. Kits and systems including the same devices and methods are also disclosed.

Abstract: A catheter hub for use with a medical device and a catheter, the hub includes a hub body defining a fluid passageway in communication with a first aperture. Optionally, the hub body defines a second aperture that intersects the first aperture. The hub body attaches to the catheter wherein the fluid passageway and the catheter are aligned for fluid flow therethrough. The first aperture extends from and communicates with the fluid passageway to an exterior surface of the hub body and the first aperture configured to receive the medical device. The second aperture extends from and communicates with the first aperture and the exterior surface. A sealing element is sized for and positioned in either the first or the second apertures. The sealing element is configured to receive the medical device and seal both of the first and the second apertures.

Abstract: A method of sealing a trachea is provided that includes inserting a tracheal tube having an inflatable cuff made of a compliant material into a trachea. The method includes inflating the inflatable cuff with a fluid to a first pressure that exceeds a second pressure necessary to create a seal between the inflatable cuff and the tracheal wall. The method includes deflating the inflatable cuff by releasing a first pressure to allow the fluid to flow out of the inflatable cuff without applying vacuum pressure to the fluid while evaluating a rate of change of pressure of the fluid in the inflatable cuff. The method includes identifying a variance in the rate of change of pressure corresponding to a third pressure at which the inflatable cuff separates from the tracheal wall, determining the second pressure by analyzing the third pressure, and reinflating the inflatable cuff to the second pressure.

Abstract: Described are devices, methods and systems for securing sutures external to the body. In certain aspects, a suture securement device includes a housing member defining an internal cavity and a wedge member moveable within the cavity between a suture-release position to a suture-retention position. The wedge member defines a suture aperture extending therethrough. At the suture-retention position, the housing member is configured to compress the wedge member to clamp the suture, thereby substantially preventing the suture from moving within the aperture.

Abstract: A dilator may include a leading portion that includes a leading end coupled to a leading stem. The dilator may further include a trailing portion that includes a trailing end coupled to a trailing shaft. The dilator may also include a segmented body disposed between the leading end and the trailing end. The segmented body may include a plurality of segments disposed circumferentially around the leading stem. The leading stem may extend through a passageway of the segmented body, an opening of the trailing end and a channel of the trailing shaft. The leading stem and the trailing shaft may be configured to move longitudinally relative to one another to radially outwardly expand the segmented body.

Abstract: An indwelling stent is provided. The stent includes a distal member that extends between a distal end portion and a proximal end portion and defines a lumen therethrough, and a proximal member that extends between a distal end portion and a proximal end portion and defines a lumen therethrough, wherein the distal member and the proximal member collectively define the stent, and wherein the distal and proximal members are discrete components and are telescopingly arranged with the distal end portion of the proximal member extending over an outer surface of the distal member.

Abstract: Described are devices, methods and systems for securing sutures external to the body. In certain aspects, a suture securement device includes a housing member defining an internal cavity and a wedge member moveable within the cavity between a suture-release position to a suture-retention position. The wedge member defines a suture aperture extending therethrough. At the suture-retention position, the housing member is configured to compress the wedge member to clamp the suture, thereby substantially preventing the suture from moving within the aperture.