Patents by Inventor Gary L. Pittenger

Gary L. Pittenger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ingap protein involved in pancreatic islet neogenesis
    Patent number: 5840531
    Abstract: Cellophane wrapping (CW) of hamster pancreas induces proliferation of duct epithelial cells followed by endocrine cell differentiation and islet neogenesis. Using the mRNA differential display technique a cDNA clone expressed in cellophane wrapped but not in control pancreata was identified. Using this cDNA as a probe, a cDNA library was screened and a gene not previously described was identified and named INGAP.
    Type: Grant
    Filed: September 9, 1996
    Date of Patent: November 24, 1998
    Assignees: MoGill University, Eastern Virginia Medical School of the Medicine College of Hampton Roads
    Inventors: Aaron I. Vinik, Gary L. Pittenger, Ronit Rafaeloff, Lawrence Rosenberg, William P. Duguid
  • Ingap protein involved in pancreatic islet neogenesis
    Patent number: 5834590
    Abstract: Cellophane wrapping (CW) of hamster pancreas induces proliferation of duct epithelial cells followed by endocrine cell differentiation and islet neogenesis. Using the mRNA differential display technique a cDNA clone expressed in cellophane wrapped but not in control pancreata was identified. Using this cDNA as a probe, a cDNA library was screened and a gene not previously described was identified and named INGAP.
    Type: Grant
    Filed: February 22, 1995
    Date of Patent: November 10, 1998
    Assignee: Eastern Virginia Medical School of the Medical College of Hampton Roads
    Inventors: Aaron I. Vinik, Gary L. Pittenger, Ronit Rafaeloff, Lawrence Rosenberg, William P. Duguid
  • High level of expression of ingap in bacterial and euraryotic cells
    Patent number: 5804421
    Abstract: Removal of the nucleotide sequence encoding the signal peptide from the INGAP coding sequence allows cultured cells to express substantial amounts of INGAP activity. Previous attempts have provided only low yields of INGAP, possibly because the signal sequence of INGAP is toxic to the cells.
    Type: Grant
    Filed: August 12, 1997
    Date of Patent: September 8, 1998
    Assignee: Eastern Virginia Medical School of the Medical College fo Hampton Roads
    Inventors: Aaron I. Vinik, Gary L. Pittenger, Ronit Rafaeloff-Phail, Scott W. Barlow
  • INGAP protein involved in pancreatic islet neogenesis
    Patent number: RE39062
    Abstract: Cellophane wrapping (CW) of hamster pancreas induces proliferation of duct epithelial cells followed by endocrine cell differentiation and islet neogenesis. Using the mRNA differential display technique a cDNA clone expressed in cellophane wrapped but not in control pancreata was identified. Using this cDNA as a probe, a cDNA library was screened and a gene not previously described was identified and named INGAP.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: April 11, 2006
    Assignees: McGill Unviersity, Eastern Virginia Medical School of the Medical College of Hampton Roads
    Inventors: Aaron I. Vinik, Gary L. Pittenger, Ronit Rafaeloff-Phail, Lawrence Rosenberg, Jean T. S. Duguid, William P. Duguid
  • INGAP protein involved in pancreatic islet neogenesis
    Patent number: RE39299
    Abstract: Cellophane wrapping (CW) of hamster pancreas induces proliferation of duct epithelial cells followed by endocrine cell differentiation and islet neogenesis. Using the mRNA differential display technique a cDNA clone expressed in cellophane wrapped but not in control pancreata was identified. Using this cDNA as a probe, a cDNA library was screened and a gene not previously described was identified and named INGAP.
    Type: Grant
    Filed: November 13, 2000
    Date of Patent: September 19, 2006
    Assignees: Eastern Virginia Medical School of the Medical College of Hampton Roads, McGill University
    Inventors: Aaron I. Vinik, Gary L. Pittenger, Ronit Rafaeloff-Phail, Lawrence Rosenberg, Jean T. S. Duguid, William P. Duguid
  • High level of expression of INGAP in bacterial and eukaryotic cells
    Patent number: RE39351
    Abstract: Removal of the nucleotide sequence encoding the signal peptide from the INGAP coding sequence allows cultured cells to express substantial amounts of INGAP activity. Previous attempts have provided only low yields of INGAP, possibly because the signal sequence of INGAP is toxic to the cells.
    Type: Grant
    Filed: September 8, 2000
    Date of Patent: October 17, 2006
    Assignee: Eastern Virginia Medical School of the Medical College of Hampton
    Inventors: Aaron I. Vinik, Gary L. Pittenger, Ronit Rafaeloff-Phail, Scott W. Barlow