Patents by Inventor Gary L. Silvey

Gary L. Silvey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions comprising 5-azacytidine monohydrate
    Patent number: 8779117
    Abstract: Provided herein are pharmaceutical compositions or dosage forms comprising crystalline 5-azacytidine monohydrate. The pharmaceutical compositions or dosage forms provided herein may be used for oral administration in the treatment of diseases, including the treatment of myelodysplastic syndromes (MDS).
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: July 15, 2014
    Assignee: Pharmion LLC
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L. Silvey
  • Pharmaceutical compositions comprising forms of 5-azacytidine
    Patent number: 8614313
    Abstract: The invention provides novel polymorphic and pseudopolymorphic crystalline forms of 5-azacytidine, along with methods for preparing said forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising said forms.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: December 24, 2013
    Assignee: Pharmion LLC
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L. Silvey
  • METHODS FOR ISOLATING CRYSTALLINE FORM I OF 5-AZACYTIDINE
    Publication number: 20130274459
    Abstract: The invention includes methods for isolating crystalline Form I of 5-azacytidine substantially free of other forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising Form I of 5-azacytidine.
    Type: Application
    Filed: June 7, 2013
    Publication date: October 17, 2013
    Inventors: Dumitru IONESCU, Peter Blumbergs, Gary L. Silvey
  • Pharmaceutical compositions comprising forms of 5-azacytidine
    Patent number: 8513406
    Abstract: The invention provides novel polymorphic and pseudopolymorphic crystalline forms of 5-azacytidine, along with methods for preparing said forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising said forms.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: August 20, 2013
    Assignee: Pharmion LLC
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L. Silvey
  • Methods for isolating crystalline form I of 5-azacytidine
    Patent number: 8481715
    Abstract: The invention includes methods for isolating crystalline Form I of 5-azacytidine substantially free of other forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising Form I of 5-azacytidine.
    Type: Grant
    Filed: June 5, 2012
    Date of Patent: July 9, 2013
    Assignee: Pharmion LLC
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L. Silvey
  • PHARMACEUTICAL COMPOSITIONS COMPRISING FORMS OF 5-AZACYTIDINE
    Publication number: 20130059810
    Abstract: The invention provides novel polymorphic and pseudopolymorphic crystalline forms of 5-azacytidine, along with methods for preparing said forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising said forms.
    Type: Application
    Filed: August 16, 2012
    Publication date: March 7, 2013
    Applicant: PHARMION LLC
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L. Silvey
  • PHARMACEUTICAL COMPOSITIONS COMPRISING FORMS OF 5-AZACYTIDINE
    Publication number: 20130059809
    Abstract: The invention provides novel polymorphic and pseudopolymorphic crystalline forms of 5-azacytidine, along with methods for preparing said forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising said forms.
    Type: Application
    Filed: August 16, 2012
    Publication date: March 7, 2013
    Applicant: PHARMION LLC
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L. Silvey
  • METHODS FOR ISOLATING CRYSTALLINE FORM I OF 5-AZACYTIDINE
    Publication number: 20120245342
    Abstract: The invention includes methods for isolating crystalline Form I of 5-azacytidine substantially free of other forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising Form I of 5-azacytidine.
    Type: Application
    Filed: June 5, 2012
    Publication date: September 27, 2012
    Applicant: PHARMION LLC
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L. Silvey
  • Pharmaceutical compositions comprising crystal forms of 5-azacytidine
    Patent number: 8211862
    Abstract: The invention includes methods for isolating crystalline Form I of 5-azacytidine substantially free of other forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising Form I of 5-azacytidine.
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: July 3, 2012
    Assignee: Pharmion LLC
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L. Silvey
  • Pharmaceutical Compositions Comprising Forms of 5-Azacytidine
    Publication number: 20100298253
    Abstract: The invention provides novel polymorphic and pseudopolymorphic crystalline forms of 5-azacytidine, along with methods for preparing said forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising said forms.
    Type: Application
    Filed: May 25, 2010
    Publication date: November 25, 2010
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L. Silvey
  • Pharmaceutical Compositions Comprising Crystal Forms of 5-Azacytidine
    Publication number: 20100292180
    Abstract: The invention includes methods for isolating crystalline Form I of 5-azacytidine substantially free of other forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising Form I of 5-azacytidine.
    Type: Application
    Filed: March 22, 2010
    Publication date: November 18, 2010
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L. Silvey
  • Forms of 5-azacytidine
    Patent number: 7772199
    Abstract: The invention provides novel polymorphic and pseudopolymorphic crystalline forms of 5-azacytidine, along with methods for preparing said forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising said forms.
    Type: Grant
    Filed: July 18, 2006
    Date of Patent: August 10, 2010
    Assignee: Celgene Corporation
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L Silvey
  • Methods for isolating crystalline form I of 5-azacytidine
    Patent number: 7700770
    Abstract: The invention includes methods for isolating crystalline Form I of 5-azacytidine substantially free of other forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising Form I of 5-azacytidine.
    Type: Grant
    Filed: August 5, 2005
    Date of Patent: April 20, 2010
    Assignee: Celgene Corporation
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L Silvey
  • Forms of 5-Azacytidine
    Patent number: 7078518
    Abstract: The disclosure includes novel polymorphic and pseudopolymorphic crystalline forms of 5-azacytidine, along with methods for preparing said forms, wherein 5-azacytidine is represented by the formula: The disclosure also includes pharmaceutical compositions comprising said forms.
    Type: Grant
    Filed: February 7, 2005
    Date of Patent: July 18, 2006
    Assignee: Pharmion Corporation
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L Silvey
  • Methods for isolating crystalline Form I of 5-azacytidine
    Patent number: 6943249
    Abstract: The invention includes methods for isolating crystalline Form I of 5-azacytidine substantially free of other forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising Form I of 5-azacytidine.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: September 13, 2005
    Assignees: Ash Stevens, Inc., Pharmion Corporation
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L. Silvey
  • Forms of 5-azacytidine
    Patent number: 6887855
    Abstract: The invention provides novel polymorphic and pseudopolymorphic crystalline forms of 5-azacytidine, along with methods for preparing said forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising said forms.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: May 3, 2005
    Assignees: Pharmion Corporation, Ash Stevens, Inc.
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L. Silvey
  • Methods for isolating crystalline form I of 5-azacytidine
    Publication number: 20040186284
    Abstract: The invention includes methods for isolating crystalline Form I of 5-azacytidine substantially free of other forms, wherein 5-azacytidine is represented by the formula: 1
    Type: Application
    Filed: March 17, 2003
    Publication date: September 23, 2004
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L. Silvey
  • Forms of 5-azacytidine
    Publication number: 20040186065
    Abstract: The invention provides novel polymorphic and pseudopolymorphic crystalline forms of 5-azacytidine, along with methods for preparing said forms, wherein 5-azacytidine is represented by the formula: 1
    Type: Application
    Filed: March 17, 2003
    Publication date: September 23, 2004
    Inventors: Dumitru Ionescu, Peter Blumbergs, Gary L. Silvey