Abstract: An endoscope device comprises a handle, a shaft projecting from the handle, wherein the shaft includes a proximal portion and a distal portion relative to the handle, a flexible tip coupled to the distal portion of the shaft, a pair of pull wires extending from the handle portion through the shaft portion and coupled to the flexible tip, a control wheel assembly rotationally secured within the handle and operatively coupled to the pair of pull wires, and a control lever coupled to the control wheel assembly via an opening in the handle. Manipulation of the control lever causes rotation of the control wheel assembly, which then causes deflection of the flexible tip via the pull wires. The control wheel assembly includes an arcuate member that covers at least a portion of the control wheel assembly to prevent external contaminants from entering the opening in the handle adjacent the control lever.

Abstract: An endoscope system, comprises an endoscope device that includes a handle, a shaft projecting from the handle, a flexible tip coupled to a distal portion of the shaft, and a pair of pull wires extending from the handle portion through the shaft portion and coupled to the flexible tip. The handle portion includes a control wheel assembly coupled to the pair of pull wires. The handle includes a control lever coupled to the control wheel assembly. Manipulation of the control lever causes rotation of the control wheel assembly, which then causes deflection of the flexible tip via the pull wires. The control wheel assembly comprises at least two control wheels. Each of the at least two control wheels are capable of independent rotation to provide accurate tensioning of the pair of pull wires during assembly of the endoscope system.

Abstract: Embodiments herein relate to systems and methods for endoscopic ultrasound-guided celiac plexus ablation and sensing. In an embodiment, a system for endoscopic ultrasound-guided ablation and sensing is included having an ultrasound endoscope that can include an ultrasound transducer and a radiofrequency catheter configured to be disposed within the ultrasound endoscope. The radiofrequency catheter can include a first electrode pair disposed on the radiofrequency catheter, where the first electrode pair configured to be placed at or near at a site of a celiac plexus. The system is configured to sense a baseline electrical property to verify placement of the first electrode pair at the celiac plexus; deliver a radiofrequency energy to the celiac plexus through the first electrode pair; and sense a post-treatment electrical property of the celiac plexus to verify neurolysis of the celiac plexus. Other embodiments are also included herein.

Abstract: An endoscope system, comprises an endoscope device that includes a handle, a shaft projecting from the handle, a flexible tip coupled to a distal portion of the shaft, and a pair of pull wires extending from the handle portion through the shaft portion and coupled to the flexible tip. The handle portion includes a control wheel assembly coupled to the pair of pull wires. The handle includes a control lever coupled to the control wheel assembly. Manipulation of the control lever causes rotation of the control wheel assembly, which then causes deflection of the flexible tip via the pull wires. The control wheel assembly comprises at least two control wheels. Each of the at least two control wheels are capable of independent rotation to provide accurate tensioning of the pair of pull wires during assembly of the endoscope system.