Patents by Inventor Gary Leroy

Gary Leroy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sequence-specific extraction and analysis of DNA-bound proteins
    Patent number: 9103827
    Abstract: An automated protein preparation technology that may use magnetic microparticles to isolate proteins in their native state from specific genomic loci of interest via the chromatin to which they are bound is described. After extraction, the targeted proteins may be purified for downstream analysis by quantitative mass spectrometry or ELISA. The identification of DNA-bound proteins, histones and their post-translational modification is of high scientific and pharmaceutical importance due to the role of DNA-binding proteins in the cauzation and development of human disease; in particular, cancer.
    Type: Grant
    Filed: November 10, 2011
    Date of Patent: August 11, 2015
    Assignees: The Trustees of Princeton University, Generation Biotech
    Inventors: Johannes Dapprich, Benjamin Garcia, Gary Leroy
  • SEQUENCE-SPECIFIC EXTRACTION AND ANALYSIS OF DNA-BOUND PROTEINS
    Publication number: 20140024052
    Abstract: An automated protein preparation technology that may use magnetic microparticles to isolate proteins in their native state from specific genomic loci of interest via the chromatin to which they are bound is described. After extraction, the targeted proteins may be purified for down-stream analysis by quantitative mass spectrometry or ELISA. The identification of DNA-bound proteins, histones and their post-translational modification is of high scientific and pharmaceutical importance due to the role of DNA-binding proteins in the causation and development of human disease; in particular, cancer.
    Type: Application
    Filed: November 10, 2011
    Publication date: January 23, 2014
    Applicants: THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Johannes Dapprich, Benjamin Garcia, Gary Leroy