Patents by Inventor Gary Leuhr

Gary Leuhr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLYCYRRHETINIC ACID DERIVATIVES FOR USE IN TREATING HYPERKALEMIA
    Publication number: 20220106354
    Abstract: The present invention provides a compound of formula (I) or a salt thereof: (Formula (I)) wherein X, L, V, R1; R2, R3 and R4, are as defined herein. The claimed compounds inhibit the enzyme 11-hydroxysteroid dehydrogenase type 2 (11-HSD2) and as a result are useful in the treatment of hyperkalemia by preventing cortisol from being oxidised to cortisone and thus allowing it to occupy the mineralocorticoid receptor, thus stimulating potassium excretion.
    Type: Application
    Filed: February 6, 2020
    Publication date: April 7, 2022
    Applicant: ARDELYX, INC.
    Inventors: Dean Dragoli, Gary Leuhr, Tao Chen, Jason Lewis, Michael Leadbetter