Patents by Inventor Gary Luker

Gary Luker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POSS nanocomposite hydrogel for 3D bioprinting
    Patent number: 11541148
    Abstract: Provided is a bioink comprising a mixture comprising a collagen and a polysaccharide, and a polyhedral oligomeric silsesquioxane (POSS), a hydrogel matrix formed from a bioink comprising a mixture comprising a collagen and a polysaccharide, and a polyhedral oligomeric silsesquioxane (POSS), a 3D biomaterial scaffold comprising a hydrogel matrix of the disclosure as a first hydrogel layer and a hydrogel matrix of the disclosure as a second hydrogel layer, optionally having an intervening layer between the first hydrogel layer and the second hydrogel layer, and methods of forming and using same.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: January 3, 2023
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Chun Liu, Kathryn Luker, Gary Luker
  • POSS NANOCOMPOSITE HYDROGEL FOR 3D BIOPRINTING
    Publication number: 20190328930
    Abstract: Provided is a bioink comprising a mixture comprising a collagen and a polysaccharide, and a polyhedral oligomeric silsesquioxane (POSS), a hydrogel matrix formed from a bioink comprising a mixture comprising a collagen and a polysaccharide, and a polyhedral oligomeric silsesquioxane (POSS), a 3D biomaterial scaffold comprising a hydrogel matrix of the disclosure as a first hydrogel layer and a hydrogel matrix of the disclosure as a second hydrogel layer, optionally having an intervening layer between the first hydrogel layer and the second hydrogel layer, and methods of forming and using same.
    Type: Application
    Filed: April 30, 2019
    Publication date: October 31, 2019
    Inventors: Chun Liu, Kathryn Luker, Gary Luker
  • Imaging regulated protein-protein interactions in cells and living animals by enhanced luciferase protein fragment complementation
    Patent number: 7442518
    Abstract: An enhanced firefly luciferase protein fragment complementation assay method is described that produces a robust and broadly applicable bioluminescence signal and demonstrates both modification-independent and phosphorylation-dependent protein interactions in intact living human cells and animals useful as a diagnostic and testing tool in living biologic systems in research and in assays.
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: October 28, 2008
    Assignee: Washington University
    Inventors: David Piwnica-Worms, Kathryn Luker, Gary Luker
  • Imaging regulated protein-protein interactions in cells and living animals by enhanced luciferase protein fragment complementation
    Publication number: 20050144661
    Abstract: An enhanced firefly luciferase protein fragment complementation assay method is described that produces a robust and broadly applicable bioluminescence signal and demonstrates both modification-independent and phosphorylation-dependent protein interactions in intact living human cells and animals useful as a diagnostic and testing tool in living biologic systems in research and in assays.
    Type: Application
    Filed: August 6, 2004
    Publication date: June 30, 2005
    Inventors: David Piwnica-Worms, Kathryn Luker, Gary Luker