Abstract: A toothbrush assembly comprising a head component, a handle component detachably attached to the head component, and a toothpaste cartridge removably received within the handle component. The head component comprises a first body member having a first cavity and a plurality of holes configured on a front end portion, and a plurality of bristles configured on the front end portion of the first body member. The handle component comprises a second body member having a second cavity, a rotatable member coupled to a distal end portion of the second body member, and a first turning lug coupled to the rotatable member. The toothpaste cartridge comprises an enclosure member for storing toothpaste therein, a rod positioned within the enclosure member, a second turning lug coupled to the rod, and a plunger member movably mounted on the rod.