Patents by Inventor Gary Nutter Buell

Gary Nutter Buell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of screening modulators of mammalian P2X7 purinergic receptors
    Patent number: 6509163
    Abstract: The present invention relates, in general, to a purinergic receptor and, particular, to a P2X7 (also designated P2Z) receptor. The invention further relates to a nucleic acid encoding the P2X7 receptor and to a method of producing P2X7 combinantly using same. The invention also relates to a method of screening compounds for their ability to inhibit P2X7 activity and thereby for their usefulness in treating a variety of diseases/disorders, including arthritic and respiratory disorders and neurodegenerative diseases.
    Type: Grant
    Filed: August 15, 2000
    Date of Patent: January 21, 2003
    Assignee: Glaxo Group Limited
    Inventors: Gary Nutter Buell, Annmarie Surprenant, Eric Kawashima
  • Purinergic receptor
    Patent number: 6133434
    Abstract: The present invention relates, in general, to a purinergic receptor and, in particular, to a P2X.sub.7 (also designated P2Z) receptor. The invention further relates to a nucleic acid encoding the P2X.sub.7 receptor and to a method of producing P2X.sub.7 recombinantly using same. The invention also relates to a method of screening compounds for their ability to inhibit P2X.sub.7 activity and thereby for their usefulness in treating a variety of diseases/disorders, including arthritic and respiratory disorders and neurodegenerative diseases.
    Type: Grant
    Filed: April 28, 1997
    Date of Patent: October 17, 2000
    Assignee: Glaxo Group Limited
    Inventors: Gary Nutter Buell, Annmarie Surprenant, Eric Kawashima