Abstract: The present disclosure features compositions and methods for the treatment of bacterial infections, such as bacterial infections caused by bacterial cells residing within a host cell (e.g., a mammalian cell, e.g., immune cell, e.g., macrophage or dendritic cell). The compositions and methods include delivering antimicrobial agents to specifically target the intracellular compartment (endosome, phagosome, lysosome, or cytosol) in which the bacterial cell resides.

Abstract: The present disclosure features compositions and methods for the treatment of bacterial infections, such as bacterial infections caused by bacterial cells residing within a host cell (e.g., a mammalian cell, e.g., immune cell, e.g., macrophage or dendritic cell). The compositions and methods include delivering antimicrobial agents to specifically target the intracellular compartment (endosome, phagosome, lysosome, or cytosol) in which the bacterial cell resides.

Abstract: The present disclosure features compositions and methods for the treatment of bacterial infections, such as bacterial infections caused by bacterial cells residing within a host cell (e.g., a mammalian cell, e.g., immune cell, e.g., macrophage or dendritic cell). The compositions and methods include delivering a bacteriophage and an antibacterial lytic protein to the intracellular computment (endosome, phagosome, lysosome, or cytosol) in which the bacterial cell resides.

Abstract: The invention features low-dosage rifalazil compositions and therapeutic regimens which are useful for the treatment of bacterial infections.

Abstract: The invention features low-dosage rifalazil compositions which are useful for the treatment of bacterial infections.

Abstract: The present invention features a metallic resistive heater and uses thereof. The resistive heater includes a metallic component that is electrically conductive (i.e., has low resistivity) and an oxide, nitride, carbide, and/or boride derivative of the metallic component that is electrically insulating (i.e., has high resistivity). The resistivity is controlled in part by controlling the amount of oxide, nitride, carbide, and boride formation during the deposition of the metallic component and the derivative.

Abstract: A system and method for heating materials is provided. Generally, the system contains a first layer upon which a material may be placed for heating the material, wherein the first layer has sufficient conductivity to allow heat to travel through the first layer. The system also contains a heater layer provided on the first layer, which is capable of providing heat to the first layer for heating the material. In addition, the system has an insulator layer for protecting the heater layer from contaminants.

Abstract: A metallic resistive heater and a method of production are described. The resistive heater has a metallic component that is electrically conductive (i.e. has low resistivity) and an oxide, nitride, carbide, and or boride derivative of the metallic component that is electrically insulating (i.e., has high resistivity). The resistivity is controlled by controlling the amount of oxide, nitride, carbide, and boride formation during the deposition of the metallic component and the derivative.

Abstract: A susceptor-impregnated thermoplastic foam is molded by heating the susceptor-impregnated thermoplastic foam, preferably by induction; imprinting an object against the foam; and allowing the foam to cool into a hardened form conformed to the object.

Abstract: The invention features low-dosage rifalazil compositions and therapeutic regimens which are useful for the treatment of bacterial infections.

Abstract: The present invention features shaped resistive heaters, uses thereof, and methods for their fabrication. The heaters are shaped such that they can conform to all or part of an object, e.g., an injection mold. The heaters may be permanently bonded to the object, or they may be adjacent to the object but not adhered, having the advantage of being removable and replaceable. The heaters include an electrically resistive element, which is, for example, a plate, a wire coil, or a deposited layer. Exemplary resistive elements are fabricated by thermal spray.

Abstract: The present invention involves coatings deposited on a substrate including a layer having a selected resistivity. The resistive layer can serve as a heat source in a variety of applications and can be fabricated using an arc plasma spraying procedure.

Abstract: A system and method for heating materials is provided. Generally, the system contains a first layer upon which a material may be placed for heating the material, wherein the first layer has sufficient conductivity to allow heat to travel through the first layer. The system also contains a heater layer provided on the first layer, which is capable of providing heat to the first layer for heating the material. In addition, the system has an insulator layer for protecting the heater layer from contaminants.

Abstract: The present invention features a metallic resistive heater and uses thereof. The resistive heater includes a metallic component that is electroconductive (i.e., has low resistivity) and an oxide, nitride, carbide, silicide, and/or boride derivative of the metal component that is electrically insulating (i.e., has high resistivity). The resistivity is controlled in part by controlling the amount of oxide, nitride, carbide, silicide, and boride formation during the deposition of the metal component and the derivative.

Abstract: The present invention features a metallic resistive heater and uses thereof. The resistive heater includes a metallic component that is electrically conductive (i.e., has low resistivity) and an oxide, nitride, carbide, and/or boride derivative of the metallic component that is electrically insulating (i.e., has high resistivity). The resistivity is controlled in part by controlling the amount of oxide, nitride, carbide, and boride formation during the deposition of the metallic component and the derivative.

Abstract: A susceptor-impregnated thermoplastic foam is molded by heating the susceptor-impregnated thermoplastic foam, preferably by induction; imprinting an object against the foam; and allowing the foam to cool into a hardened form conformed to the object.

Abstract: A susceptor-impregnated thermoplastic foam is molded by heating the susceptor-impregnated thermoplastic foam, preferably by induction; imprinting an object against the foam; and allowing the foam to cool into a hardened form conformed to the object.

Abstract: The present invention involves coatings deposited on a substrate including a layer having a selected resistivity. The resistive layer can serve as a heat source in a variety of applications and can be fabricated using an arc plasma spraying procedure.

Abstract: Apparatus for manufacturing heat sealed products from high temperature film materials exhibiting superior barrier properties, such as films made from LCP resin. The apparatus has in relevant part a first compression member having a heating element that is capable of being continuously or intermittently heated to a temperature of about 300.degree. C. (c. 575.degree. F.) backed by a layer of material capable of supporting the heating element, a second compression member that opposes the first compression member and having an electrically conductive tubular sealing element, capable of being flash-heated by means of a pulse of electric current to a temperature of about 425.degree. C. (c. 800.degree. F.) and immediately flash-cooled to room temperature or below by means of forcing vortex-chilled coolant fluid through the tubular lumen, backed by a layer of material capable of supporting the sealing element, and two floating sheets or tapes of high-temperature release material disposed therebetween.

Abstract: A novel method for forming a gel matrix. In this method an apparatus is provided which includes a first and second plate, each plate having a flat surface, and a spacer. The spacer is positioned between the flat surfaces of the two plates so that the flat surfaces are located close to each other with a gap from the top of the plates to the bottom of the plates. The apparatus is placed into a generally rectangular liquid impermeable bag having one top open end, a bottom end and a side wall therebetween. The apparatus is placed into this bag such that the top of the plates is parallel to the top open edge of the bag, and the bottom of the plates is located adjacent the bottom end of the bag. The apparatus is fixed, e.g., clamped, in place firmly within the bag and a gelling solution poured into the gap between the plates. This gelling solution is then allowed to set to form the desired gel matrix.