Abstract: The present disclosure relates to novel compounds for use in therapeutic treatment of a disease associated with peptidylarginine deiminases (PADs), such as peptidylarginine deiminase type 4 (PAD4). The present disclosure also relates to processes and intermediates for the preparation of such compounds, methods of using such compounds and pharmaceutical compositions comprising the compounds described herein.

Abstract: A motion capture system comprising: a master clock configured to repeatedly generate and output, at a frame rate, a primary clock signal that conveys when a video frame starts; a first camera configured to capture light within a first set of wavelengths and operably coupled to receive the master clock signal and initiate an image capture sequence on a frame-by-frame basis in fixed phase relationship with the primary clock signal to generate a first set of images at the frame rate from light captured within the first set of wavelengths; a synchronization module operably coupled to receive the master clock signal from the master clock and configured to generate a synchronization signal offset in time from and in a fixed relationship with the primary clock signal; and a second camera configured to capture light within a second set of wavelengths, different than the first set of wavelengths, and operably coupled to receive the synchronization signal and initiate an image capture sequence on the frame-by-frame bas