Patents by Inventor Gary P. Stack

Gary P. Stack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azabicyclylmethyl derivatives of 7,8-dihydro-1,6,9,-trioxa-3-aza-cyclopenta[a]naphthalene as 5-HT antagonists
    Patent number: 7381723
    Abstract: Compounds of the formula are useful for treating the cognitive deficits due to aging, stroke, head trauma, Alzheimer's disease or other neurodegenerative diseases, or schizophrenia and are also useful for the treatment of disorders such as anxiety, aggression and stress, and for the control of various physiological phenomena, such eating disorders, disorders of thermoregulation, and sleep and sexual dysfunction.
    Type: Grant
    Filed: June 28, 2004
    Date of Patent: June 3, 2008
    Assignee: Wyeth
    Inventors: Gary P. Stack, Megan Tran, Adam M. Gilbert
  • Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1, 4-benzodiozan
    Patent number: 7041683
    Abstract: Compounds of the formula useful for the treatment of depression and other conditions such as obsessive compulsive disorder, panic attacks, generalized anxiety disorder, sexual dysfunction, eating disorders, addictive disorders caused by ethanol or cocaine abuse and related illnesses.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: May 9, 2006
    Assignee: Wyeth
    Inventors: George E. M. Husbands, Gary P. Stack, Richard E. Mewshaw, Ian A. Cliffe
  • Antidepressant azahetorocyclylmethyl derivatives of 7,8-dihydro-6H-5-oxa-1-aza-phenathrene
    Patent number: 7030245
    Abstract: Compounds of the formula useful for the treatment of such as depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre-menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder (including trichotillomania), social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa, bulimia nervosa, vasomotor flushing, cocaine and alcohol addition, sexual dysfunction (including premature ejaculation), and related illnesses.
    Type: Grant
    Filed: June 6, 2005
    Date of Patent: April 18, 2006
    Assignee: Wyeth
    Inventors: Rulin Zhao, Megan Tran, Gary P. Stack, Richard E. Mewshaw
  • [1,4]Diazocino[7,8,1-hi]indole derivatives as antipsychotic and antiobesity agents
    Patent number: 7012089
    Abstract: Compounds of formula (I) or pharmaceutically acceptable salts thereof are provided: where R1 through R7 are defined herein. The compounds of formula (I) are 5HT2c agonists or partial agonists, and are useful for treating a variety of disorders.
    Type: Grant
    Filed: April 24, 2003
    Date of Patent: March 14, 2006
    Assignee: Wyeth
    Inventors: Hong Gao, Gary P. Stack, Annmarie L. Sabb
  • Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-Dioxino[2,3-f]quinoxaline
    Patent number: 7008944
    Abstract: Compounds of the formula: are useful for the treatment of depression and other diseases such as obsessive compulsive disorder, panic attacks, generalized anxiety disorder, social anxiety disorder, sexual dysfunction, eating disorders, obesity, addictive disorders caused by ethanol or cocaine abuse and related illnesses.
    Type: Grant
    Filed: July 14, 2003
    Date of Patent: March 7, 2006
    Assignee: Wyeth
    Inventors: Jonathan L. Gross, Gary P. Stack
  • Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine
    Patent number: 6987117
    Abstract: Compounds of the formula useful for the treatment of depression, obsessive compulsive disorder, panic attacks, generalized anxiety disorder, social anxiety disorder, sexual dysfunction, eating disorders, obesity, addictive disorders caused by ethanol or cocaine abuse, and dysthymia.
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: January 17, 2006
    Assignee: Wyeth
    Inventors: Megan Tran, Gary P. Stack
  • Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene
    Patent number: 6943178
    Abstract: Compounds of the formula useful for the treatment of diseases such as depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder (including trichotillomania), social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa, bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.
    Type: Grant
    Filed: June 30, 2004
    Date of Patent: September 13, 2005
    Assignee: Wyeth
    Inventors: Megan Tran, Gary P. Stack
  • Antidepressant azaheterocyclyl methyl derivatives of 7,8-dihydro-6H-5-oxa-1-aza-phenanthrene
    Patent number: 6930109
    Abstract: Compounds of the formula useful for the treatment of such as depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre-menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder (including trichotillomania), social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa, bulimia nervosa, vasomotor flushing, cocaine and alcohol addition, sexual dysfunction (including premature ejaculation), and related illnesses.
    Type: Grant
    Filed: June 28, 2004
    Date of Patent: August 16, 2005
    Assignee: Wyeth
    Inventors: Rulin Zhao, Megan Tran, Gary P. Stack, Richard E. Mewshaw
  • Antidepressant azaheterocyclymethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diazacyclopenta[a]naphthalene
    Patent number: 6927226
    Abstract: Compounds of the formula: are useful for the treatment of depression and other diseases such as obsessive compulsive disorder, panic attacks, generalized anxiety disorder, social anxiety disorder, sexual dysfunction, eating disorders, obesity, addictive disorders caused by ethanol or cocaine abuse and related illnesses.
    Type: Grant
    Filed: April 22, 2003
    Date of Patent: August 9, 2005
    Assignee: Wyeth
    Inventor: Gary P. Stack
  • Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene
    Patent number: 6906206
    Abstract: Compounds of the formula useful for the treatment of diseases such as depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder (including trichotillomania), social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa, bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.
    Type: Grant
    Filed: March 3, 2003
    Date of Patent: June 14, 2005
    Assignee: Wyeth
    Inventors: Megan Tran, Gary P. Stack
  • Antidepressant azaheterocyclylmethyl derivatives of 7,8-dihydro-6H-5-oxa-1-aza-phenanthrene
    Patent number: 6903110
    Abstract: Compounds of the formula useful for the treatment of such as depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as premenstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder (including trichotillomania), social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa, bulimia nervosa, vasomotor flushing, cocaine and alcohol addition, sexual dysfunction (including premature ejaculation), and related illnesses.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: June 7, 2005
    Assignee: Wyeth
    Inventors: Rulin Zhao, Megan Tran, Gary P. Stack, Richard E. Mewshaw
  • Azabicyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-HT1A antagonists
    Patent number: 6861427
    Abstract: Compounds of the formula are useful for treating the cognitive deficits due to aging, stroke, head trauma, Alzheimer's disease or other neurodegenerative diseases, or schizophrenia, and are also useful for the treatment of disorders such as anxiety, aggression and stress, and for the control of various physiological phenomena, such eating disorders, disorders of thermoregulation, and sleep and sexual dysfunction.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: March 1, 2005
    Assignee: Wyeth
    Inventors: Gary P. Stack, Adam M. Gilbert, Megan Tran
  • Antipsychotic aminomethyl derivatives of 1,3,7,8-tetrahydro-6,9-dioxa-1,3-diaza-cyclopenta[a]-naphthalen-2-one
    Patent number: 6861434
    Abstract: Compounds of the formula: useful for treatment of disorders of the dopaminergic system, such as schizophrenia, schizoaffective disorder, bipolar disorder, Parkinson's disease, L-DOPA induced pychoses and dyskinesias, Tourette's syndrome and hyperprolactinemia and in the treatment of drug addiction such as the addiction to ethanol, nicotine or cocaine and related illnesses.
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: March 1, 2005
    Assignee: Wyeth
    Inventor: Gary P. Stack
  • Antidepressant azaheterocyclyl methyl derivatives of 7,8-dihydro-6H-5-oxa-1-aza-phenanthrene
    Publication number: 20040235851
    Abstract: Compounds of the formula 1
    Type: Application
    Filed: June 28, 2004
    Publication date: November 25, 2004
    Applicant: WYETH
    Inventors: Rulin Zhao, Megan Tran, Gary P. Stack, Richard E. Mewshaw
  • Azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]-quinoline as 5-HT1A antagonists
    Patent number: 6821981
    Abstract: Compounds of the formula useful for the treatment of disorders, such as anxiety, aggression and stress, and for the control of various physiological phenomena, such as appetite, thermoregulation, sleep and sexual behavior.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: November 23, 2004
    Assignee: Wyeth
    Inventors: Gary P. Stack, Megan Tran, Jonathan L. Gross, George E. M. Husbands
  • Azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene as 5-HT1A antagonists
    Patent number: 6815448
    Abstract: Compounds of the formula are useful for treating the cognitive deficits due to aging, stroke, head trauma, Alzheimer's disease or other neurodegenerative diseases, or schizophrenia. The compounds of the invention are also useful for the treatment of disorders such as anxiety, aggression and stress, and for the control of various physiological phenomena, such as appetite, thermoregulation, sleep and sexual behavior.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: November 9, 2004
    Assignee: Wyeth
    Inventors: Gary P. Stack, Megan Tran
  • Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diaza-cyclopenta[a]naphthalene
    Patent number: 6803368
    Abstract: Compounds of the formula useful for treatment of disorders of the dopaminergic system, such as schizophrenia, schizoaffective disorder, bipolar disorder, Parkinson's disease, L-DOPA induced pychoses and dyskinesias, Tourette's syndrome and hyperprolactinemia and in the treatment of drug addiction such as the addiction to ethanol, nicotine or cocaine and related illnesses.
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: October 12, 2004
    Assignee: Wyeth
    Inventors: Gary P. Stack, James A. Nelson
  • Antipsychotic aminomethyl derivatives of 7,8-dihydro-2,6,9-trioxa-3-aza-cyclopenta[a]naphthalene
    Patent number: 6800642
    Abstract: Compounds of the formula: useful for treatment of disorders such as schizophrenia, schizoaffective disorder, bipolar disorder, Parkinson's disease, L-DOPA induced pychoses and dyskinesias, Tourette's syndrome and hyperprolactinemia and in the treatment of drug addiction such as the addiction to ethanol, nicotine or cocaine and related illnesses.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: October 5, 2004
    Assignee: Wyeth
    Inventors: Megan Tran, Gary P. Stack
  • Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-2,3-diaza-cyclopenta[a]naphthalene
    Patent number: 6800641
    Abstract: Compounds of the formula: useful for treatment of disorders of the dopaminergic system, such as schizophrenia, schizoaffective disorder, bipolar disorder, Parkinson's disease, L-DOPA induced pychoses and dyskinesias, Tourette's syndrome and hyperprolactinemia and in the treatment of drug addiction such as the addiction to ethanol, nicotine or cocaine and related illnesses.
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: October 5, 2004
    Assignee: Wyeth
    Inventors: Megan Tran, Gary P. Stack
  • Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-1,6,9-trioxa-3-AZA-cyclopenta[a]naphthalen-2-one
    Patent number: 6800648
    Abstract: Compounds of the formula useful for treatment of disorders of the dopaminergic system, such as schizophrenia, schizoaffective disorder, bipolar disorder, Parkinson's disease, L-DOPA induced pychoses and dyskinesias, Tourette's syndrome and hyperprolactinemia and in the treatment of drug addiction such as the addiction to ethanol, nicotine or cocaine and related illnesses.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: October 5, 2004
    Assignee: Wyeth
    Inventors: Megan Tran, Gary P. Stack