Abstract: A laryngeal cutting blade has an outer blade assembly including a tubular member having a bend closer to a proximal portion than a distal end, a hollow inner blade assembly rotatably received in the outer blade assembly for mounting to a powered handpiece and having a flexible portion disposed adjacent the bend and a suction passage extending through the inner blade assembly to permit aspiration of cut tissue, the angled configuration of the laryngeal cutting blade and toothed and smooth profile cutting ends therefore are particularly effective for debulking large, firm lesions and for delicate shaving of superficial lesions of the vocal cords after removal of bulk mass.

Abstract: A dry particulate pharmaceutical composition for pulmonary administration is prepared by spray-drying a hydrophobic active agent (e.g. declomethasone dipropionate) with a small quantity of pharmaceutically acceptable hydrophilic polymer (e.g. poly (vinyl) alcohol). This mitigates aggregation of the particles of active agent, which otherwise limits the desirable find particles dose available.

Abstract: Elongated drug, especially salbutamol sulphate, and/or carrier particles, especially lactose, pharmaceutical compositions comprising the same, and use of the elongated particles in the manufacture of a medicament for the treatment of respiratory disease.

Abstract: An angled rotary tissue cutting instrument includes an outer member or blade, having a rigid outer tube with proximal and distal portions connected by a bend, and an inner member or blade rotatably disposed within the outer member and including an inner tube of integral one-piece construction having a spiral cut formed therein between proximal and distal ends thereof to define a flexible region adjacent the bend, and at least one layer of a spirally wound strip of material superimposed over the spiral cut portion of the inner tube. The spiral cut preferably extends to a cutting tip at the distal end of the inner tube so that the inner member can be bent closer to the distal end thereof to access difficult to reach areas of the head and neck, and other parts of the body.

Abstract: According to the present invention a process is provided for making paper or paper board comprising forming a cellulosic suspension, flocculating the suspension, draining the suspension on a screen to form a sheet and then drying the sheet, characterised in that the suspension is flocculated using a flocculation system comprising a siliceous material and organic microparticies which have an unswollen particle diameter of less than 750 nanometers.

Abstract: There is disclosed apparatus for moving an optical element in an opto-mechanical system, comprising at least one circularly symmetric flexure surrounding said optical element, and means for moving said optical element along an axis perpendicular to and extending through the centre of said at least one flexure. A number of flexures may be provided in a stack with spacers therebetween, and the optical element may be mounted in a tubular member support by two paced apart stacks. Means are also provided for damping end of movement vibrations.

Abstract: The present invention provides a bonding head for a wedge wire bonding apparatus in which the bonding force of the transducer assembly, and also the clamping force of the wire clamping assembly are provided by permanent magnet motors including a coil formed as part of the transducer assembly and the wire clamping assembly respectively and with the coils located between magnets fixed to a bond head bracket member. The use of permanent magnet motors to provide the bonding and clamping forces results in apparatus in which the bonding and clamping forces can be controlled with high accuracy and reliability.

Abstract: The present invention provides methods for initiating embryogenic cultures of plants. The methods include the use of novel media compositions and elevated atmospheric pressure treatments to improve the frequency of embryogenic culture initiation. The methods are well suited for initiating embryogenic cultures in recalcitrant conifer varieties. The method is also well suited for producing somatic embryos that can be further cultured to produce large numbers of plants. Further, the invention provides novel methods that may be used to enhance somatic embryogenesis in a broad range of species.

Abstract: Force sensing apparatus is provided for sensing deflection of a transducer in an ultrasonic welding machine. The apparatus includes a body member, a transducer holder and a force sensor. The transducer holder is adapted to hold an ultrasonic transducer and the transducer holder is fixed to the body member. The force sensor is located between adjacent surfaces of the body member and the transducer holder to sense a force applied between the surfaces.

Abstract: A replaceable eddy current probe for inspecting small (¾ inch diameter or smaller) tubes of heat exchangers has a head portion with bobbin coils and a delivery conduit connector portion with a flexible conduit having a first end extending from the head portion and a second end extending to the connector portion. The connector portion has electrical terminal connections electrically connected to the bobbin coils by wires extending through the flexible conduit. The connector portion also has a housing with a surface surrounding the electrical terminal connections and the surface has a 360° delivery conduit mechanical interlock which may be a recess or a proturburance for mating with a proturberance or recess of a delivery conduit. The 360° interlock provides a robust connection which will not separate during high speed pushing and pulling forces and twisting through tight turns of U-bends.

Abstract: Force sensing apparatus is provided for sensing deflection of a transducer (8) in an ultrasonic welding machine. The apparatus includes a body member (2), a transducer holder (1) and a force sensor (4). The transducer holder (1) is adapted to hold an ultrasonic transducer (8) and the transducer holder (1) is fixed to the body member (2). The force sensor (4) is located between adjacent surfaces (11, 12) of the body member (2) and the transducer holder (1) to sense a force applied between the surfaces (11, 12).

Abstract: A dermabrasion instrument includes an outer member and an inner member rotatably disposed in the outer member with an abrading member of the inner member exposed from the outer member. An aspirating passage in the abrading member establishes communication with an aspirating channel of the inner member from externally of the abrading member so that debris from abrasion of the skin by the abrading member is evacuated through the inner member. The outer member may include a shield disposed over the abrading member to contain the debris. The instrument may include an irrigating port for discharging irrigating fluid adjacent the abrading member. A dermabrasion instrument assembly includes an abrading instrument releasably coupled to a powered surgical handpiece. The instrument has an aspirating channel and the handpiece has a suction port connectible with a source of suction to effect evacuation of debris through the abrading instrument and the handpiece.

Abstract: A synthetic silicate pellet is provided having component of calcium and magnesium, either together or in the alternative. Such pellet is further provided with either an aluminate silicate binder and/or an ion flow catalyst. The synthetic silicate pellet has use as a glass batch component.

Abstract: According to the present invention a process is provided for making paper or paper board comprising forming a cellulosic suspension, flocculating the suspension, draining the suspension on a screen to form a sheet and then drying the sheet,

Abstract: A process of making paper or paper board comprising forming a cellulosic suspension, flocculating the suspension, draining the suspension on a screen to form a sheet and then drying the sheet, characterised in that the suspension is flocculated using a flocculation system comprising a siliceous material and an anionic branched water soluble polymer that has been formed from water soluble ethylenically unsaturated anionic monomer or monomer blend and branching agent and wherein the polymer has (a) intrinsic viscosity above 1.5 dl/g and/or saline Brookfield viscosity of above about 2.0 mPa.s and (b) rheological oscillation value of tan delta at 0.005 Hz of above 0.7 and/or (c) deionised SLV viscosity number which is at least three times the salted SLV viscosity number of the corresponding unbranched polymer made in the absence of branching agent.

Abstract: A process of making paper or paper board comprising forming a cellulosic suspension, flocculating the suspension, draining the suspension on a screen to form a sheet and then drying the sheet, characterized in that the suspension is flocculated using a flocculation system comprising a clay and an anionic branched water soluble polymer that has been formed from water soluble ethylenically unsaturated anionic monomer or monomer blend and branching agent and wherein the polymer has (a) intrinsic viscosity above 1.5 dl/g and/or saline Brookfield viscosity of above about 2.0 mPa.s and (b) rheological oscillation value of tan delta at 0.005 Hz of above 0.7 and/or (c) deionised SLV viscosity number which is at least three times the salted SLV viscosity number of the corresponding unbranched polymer made in the absence of branching agent.

Abstract: A flexible inner tubular member for being rotated in an outer tubular member of a rotary tissue cutting instrument includes an elongate inner tube having a rotatably driveable proximal end, a distal end having a cutting member exposed from the outer tubular member to cut anatomical tissue and a flexible region allowing the inner tubular member to rotate within the outer tubular member while conforming to the shape of the outer member. The flexible region is defined by a helical cut in the inner tube defining a plurality of integrally, unitarily connected tube segments angularly movable relative to one another and a spiral wrap disposed over the helical cut.

Abstract: An assembly to effect adjustments to the end play, or preloading, of a bearing set. The adjusting assembly utilizes a threaded bearing cup body and a correspondingly threaded adjusting ring. The bearing cup body abuts the outer race of the bearing and the adjusting ring is threaded onto the bearing cup body and abuts a fixed or stationary housing surface. The adjusting ring is rotated to adjust bearing preload and provide proper spacing. The bearing cap is then placed to lock the bearing adjusting assembly in place.

Abstract: The present invention relates generally to a method for the treatment and prophylaxis of inflammatory conditions. The present invention is predicated in part on the identification of cells of the monocyte/macrophage lineage being critical for inflammation and, in particular, chronic inflammation. In accordance with the present invention, it is proposed that the reduction in levels of monocyte/macrophage-type cells and/or a reduction in the production of inflammatory and pro-inflammatory mediators by these cells, especially locally, is effective in reducing inflammatory conditions. The present invention further provides animal models useful for screening for reducing levels of monocyte/macrophage-type cells and/or reducing the production of inflammatory and pro-inflammatory mediators of these cells.

Abstract: The present invention is generally characterized in an angled rotary tissue cutting instrument including an outer blade assembly, having a rigid tubular member with proximal and distal portions connected by a bead, and an inner blade assembly rotatably disposed within the outer blade assembly and including a tubular drive shaft at a proximal end, a cutting tip at a distal end, and a flexible coupling disposed between the drive shaft and the cutting tip. The drive shaft and cutting tip include neck portions which are disposed telescopically within proximal and distal ends of the coupling.