Abstract: N-Heterocyclic derivatives of the following formula: where m, n, p, A1, R1, R2, R3 and R4 are described herein, as well as other N-heterocyclic derivatives, are useful as inhibitors of nitric oxide synthase. Pharmaceutical compositions containing these compounds, methods of using these compounds as inhibitors of nitric oxide synthase and processes for synthesizing these compounds are also described herein.

Abstract: An aerosol formulation comprising a biodegradable microsphere comprising a non-living reagent, such as a sub-unit vaccine, that produces a protective immune response in a mammal to whom it is administered. Nebulizers and inhalers containing such formulations are also described and claimed.

Abstract: Piperidine derivatives of the following formulae I and II: and their pharmaceutically acceptable salts, which are functional antagonists of the CC chemokine receptor CCR1 and are thus useful as anti-inflammatory agents, a pharmaceutical compositions containing said piperidine derivatives or their pharmaceutically acceptable salts, and methods of their use.

Abstract: N-Heterocyclic derivatives of the following formula: where m, n, p, A1, R1, R2, R3 and R4 are described herein, as well as other N-heterocyclic derivatives, are useful as inhibitors of nitric oxide synthase. Pharmaceutical compositions containing these compounds, methods of using these compounds as inhibitors of nitric oxide synthase and processes for synthesizing these compounds are also described herein.

Abstract: A system, method and computer program product for describing a process visually, converting the visual description to an intermediate format, and directing the process.

Abstract: Interlocking paver system for the use of constructing sidewalks, pathways and decks being formed from a light weight material for easy handling. Joined together by a plastic spline with gripping teeth, which when placed in spline receiver slots on sides of paver, which has a protruding upper edge that surrounds the entire perimeter allowing the pavers to tilt up or down, which allows the pavers to be placed on uneven or unlevel surfaces and prevents pavers from separating and from moving side to side, back and forth, and from settling downward and lifting upward which establishes a stable walking surface that is easy to install or assemble.

Abstract: The present invention relates to compounds which are CCR-5 receptor antagonists of the general formula I: wherein R1, R2, R3, R4, Ra, Rb, Rc, Rd, X, m and n are as defined herein. The invention further comprises pharmaeceutical compositions comprising such compounds, as well as the use of such compounds to treat CCR-5 mediated disorders.

Abstract: A poolside goal system may allow various games or sports, such as basketball or volleyball, to be played in a swimming pool. For example, the poolside goal system may include a base, a goal support, a basketball goal assembly and volleyball net assembly. The basketball goal assembly is preferably movable between a first position in which basketball can be played and a second position which allows volleyball to be played. Advantageously, the basketball goal assembly may be configured to counterbalance forces applied to the volleyball net assembly. The poolside goal system may also include a wheel assembly to allow the system to be readily moved, or the goal system may be permanently secured in a fixed position. The poolside goal system, however, does not have to be used in connection with a swimming pool and it could be used in other environments or situations.

Abstract: The present invention relates to a series of compounds which are CCR-5 receptor antagonists of the general formula I: or a pharmaceutically acceptable salt thereof, wherein the variables are defined herein.

Abstract: The present invention provides for novel prodrugs of 1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine of the following Formula I 1

Abstract: The present invention relates to CCR5 receptor antagonists of formulae (1a) or (1b): 1

Abstract: A utility knife comprising a bar having a forward end, a rearward end, an upper side, and a lower side; a blade having a cutting edge; screw clamps for removably mounting the blade upon the forward end of the bar; a pull handle extending upwardly and forwardly from the rearward end of the bar; a cutting edge guard pivotally mounted upon the bar; and a blade shroud fixedly mounted upon the bar.

Abstract: A method of controlling Take-all disease of plants, by applying, preferably to the seeds prior to planting, a fungicide of the formula wherein Z1, and Z2 are C and are part of an aromatic ring which is benzene.

Abstract: A microcontroller system includes a security lock circuit to regulate access requests to contents of locations of a program memory. The regulation is selective, based on an operating mode of the security lock circuit, and also based on the source of the access request and the location of the program memory for which the access request is intended. Among other advantages, one major advantage provided by the security lock circuit is that concurrent programming (i.e., programming of one area of memory using instructions executing from another area of memory) can be initiated under predetermined secure conditions.

Abstract: A method of controlling Take-all disease of plants by applying, preferably to the seed prior to planting, a fungicide of the formula wherein Z1 and Z2 are C or N and are part of an aromatic ring selected from benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole, and isothiazole; A is selected from —C(X)-amine, —C(O)—SR3, —NH—C(X)R4, and —C(═NR3)—XR7; B is —Wm—Q(R2)3 or selected from o-tolyl, 1-naphthyl, 2-naphthyl, and 9-phenanthryl, each optionally substituted with halogen or R4; Q is C, Si, Ge, or Sn; W is —C(R3)pH(2−p)—; or when Q is C, W is selected from —C(R3)pH(2−p)—, —N(R3)mH(1−m)—, —S(O)p—, and —O—; X is O or S; n is 0, 1, 2, or 3; m is 0 or 1; p is 0, 1, or 2; each R is independently selected from a) halo, formyl, cyano, amino, nitro, thiocyanato, isothiocyanato, trimethylsilyl, and hydroxy; b) C1-C4 alkyl, alkenyl, alkynyl,

Abstract: A microcontroller system has a first and a second block of non-volatile programmable memory and includes a program memory space allocation circuitry. In a first mode of operation, the first and second blocks of programmable memory are prevented from being written by commands external to the microcontroller system. In a second mode, however, the first and second blocks of programmable memory are prevented from being written by commands external to the microcontroller system but the second block of programmable memory can be written based upon execution of commands stored in the first block of programmable memory. By having circuitry to so allocate the programmable memories, the security of the programmable memories is enhanced.

Abstract: A method of controlling Take-all disease of plants by applying, preferably to the seed prior to planting, a fungicide of the formula 1