Patents by Inventor Gary R. Fabian

Gary R. Fabian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the selecting of genes encoding catalytic antibodies
    Patent number: 5258289
    Abstract: The present invention describes methods of screening for or selecting a catalytic antibody effective to cleave a target peptide. In particular, in the selection method of the present invention a phage gene is selected that encodes a gene product necessary for the production of a phage. The phage, carrying the modified gene is introduced into a host. Also, a library of rearranged immunoglobulin genes in a cloning vector is introduced into host cells. The host cells are grown under conditions in which the immunoglobulin genes are expressed in the host cells. The presence of antibodies capable of cleaving the target peptide is identified on the basis of production of phage.
    Type: Grant
    Filed: October 22, 1991
    Date of Patent: November 2, 1993
    Inventors: Claude G. Davis, Gary R. Fabian