Patents by Inventor Gary R. Matyas

Gary R. Matyas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FENTANYL HAPTENS FOR THE PREPARATION OF A FENTANYL VACCINE
    Publication number: 20230100186
    Abstract: Described is the preparation of novel fentanyl haptens of Formula (1) through (6) and their use in the preparation of effective fentanyl vaccines.
    Type: Application
    Filed: January 13, 2021
    Publication date: March 30, 2023
    Inventors: Oscar Torres, Gary R. Matyas, Kenner C. Rice, Eric W. Bow, Agnieszka Sulima, Arthur E. Jacobson
  • Antibodies Against Fentanyl and Fentanyl Analogs
    Publication number: 20220362374
    Abstract: The present disclosure is directed to isolated recombinant antibodies, or antigen-binding fragments thereof, that bind to fentanyl or fentanyl analogs. The novel antibodies or antigen-binding fragments thereof can be used to detect, diagnose, treat, and/or prevent opioid use disorder.
    Type: Application
    Filed: April 28, 2022
    Publication date: November 17, 2022
    Applicants: The Government of the United States, as represented by the Secretary of the Army, The United States of America, as represented by the Secretary, Department of Health
    Inventors: Gary R. MATYAS, Rodell C. BARRIENTOS, Oscar B. TORRES, Connor WHALEN, Therese OERTEL, Kenner C. RICE, Arthur E. JACOBSON, Eric W. BOW, Agnieszka SULIMA
  • Truncated HIV envelope proteins (ENV), methods and compositions related thereto
    Patent number: 10081658
    Abstract: The instant application provides methods and related compositions pertaining to novel HIV envelope proteins. In some embodiments, the invention relates to methods and compositions for the preparation, production, and administration of isolated novel HIV envelope nucleic acid and protein sequences suitable, for example, as vaccines against HIV.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: September 25, 2018
    Assignees: Advanced BioScience Laboratories, Inc., The United States of America as Represented by the Secretary of the Army, The Henry M. Jackson Foundation for the Advancement of Military Medicines, Inc.
    Inventors: Vaniambadi Kalyanaraman, Stephen Whitney, Thomas C. VanCott, Victoria Polonis, Carl Alving, Gary R. Matyas, Mangala Rao, Mary Marovich, Francine McCutchan, Sodsai Tovanabutra, Eric Sanders-Buell
  • Induction of highly specific antibodies to a hapten but not to a carrier peptide by immunization
    Patent number: 9193739
    Abstract: In this application is described a composition and method for inducing in a subject anti-hapten antibodies without inducing antibodies to the carrier protein. Kits for designing and making compositions with desired haptens are also described.
    Type: Grant
    Filed: February 8, 2013
    Date of Patent: November 24, 2015
    Assignees: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT OF HEALTH HUMAN SERVICES
    Inventors: Carl R. Alving, Gary R. Matyas, Arthur E. Jacobson, Fuying Li, Malliga R. Iyer, Kenner C. Rice, Kejun Cheng, Alexander Mayorov
  • Induction of highly specific antibodies to a hapten but not to a carrier peptide by immunization
    Publication number: 20150098935
    Abstract: In this application Is described a composition and method for Inducing In a subject anti-hapten antibodies without Inducing antibodies to the carrier protein. Kits for designing and making compositions with desired haptens are also described. In this application Is disclosed a synthetic liposome composition comprising liposomes (L) containing monophosphoryl lipid A (MPLA) [L(MPLA)] and an immunoconjugate comprising a carrier and a hapten. In one embodiment, the carrier is a 23 amino acid hydrophobic membrane proximal external region peptide (MPER) derived from the gp41 transmembrane protein of HIV-1 that spontaneously associates with the outer surface of bilayers of liposomes containing MPLA during liposome formation.
    Type: Application
    Filed: February 8, 2013
    Publication date: April 9, 2015
    Applicant: Walter Reed Army Institute of Research
    Inventors: Carl R. Alving, Gary R. Matyas, Arthur E. Jacobson, Fuying Li, Malliga R. Iyer, Kenner C. Rice, Kejun Cheng, Alexander Mayorov
  • TRUNCATED HIV ENVELOPE PROTEINS (ENV), METHODS AND COMPOSITIONS RELATED THERETO
    Publication number: 20140220107
    Abstract: The instant application provides methods and related compositions pertaining to novel HIV envelope proteins. In some embodiments, the invention relates to methods and compositions for the preparation, production, and administration of isolated novel HIV envelope nucleic acid and protein sequences suitable, for example, as vaccines against HIV.
    Type: Application
    Filed: April 25, 2012
    Publication date: August 7, 2014
    Applicants: ADVANCED BIOSCIENCE LABORATORIES, INC., HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, THE GOVERNMENT OF THE USA, AS REPRESENTED BY THE SECRETARY
    Inventors: Vaniambadi Kalyanaraman, Stephen Whitney, Thomas C. Vancott, Victoria Polonis, Carl Alving, Gary R. Matyas, Mangala Rao, Mary Marovich, Francine McCutchan, Sodsai Tovanabutra, Eric Sanders-Buell
  • Detection of human antibodies to squalene in serum
    Patent number: 7824864
    Abstract: The invention is a method and assay for detecting human squalene antibodies in sera or plasma using a blocking agent of ?0.5% casein in a phosphate buffered saline (PBS) solution.
    Type: Grant
    Filed: January 7, 2005
    Date of Patent: November 2, 2010
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Carl R Alving, Gary R Matyas, Nabila M Wassef, Mangala Rao
  • Detection of antibodies to squalene in serum
    Patent number: 7270964
    Abstract: The invention is a method for detecting squalene in sera.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: September 18, 2007
    Assignee: United States of America as Represented by the Secretary of the Army
    Inventors: Carl R Alving, Gary R Matyas, Nabila M Wassef, Mangala Rao
  • Detection of antibodies to squalene in serum
    Patent number: 6900025
    Abstract: The invention is a method for detecting squalene in sera.
    Type: Grant
    Filed: May 18, 2001
    Date of Patent: May 31, 2005
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Carl R. Alving, Gary R. Matyas, Nabila M. Wassef, Mangala Rao
  • Detection of antibodies to squalene in serum
    Publication number: 20040248224
    Abstract: The invention is a method for detecting squalene in sera.
    Type: Application
    Filed: July 9, 2004
    Publication date: December 9, 2004
    Inventors: Carl R. Alving, Gary R. Matyas, Nabila M. Wassef, Mangala Rao
  • Detection of antibodies to squalene in serum
    Publication number: 20020022241
    Abstract: The invention is a method for detecting squalene in sera.
    Type: Application
    Filed: May 18, 2001
    Publication date: February 21, 2002
    Inventors: Carl R. Alving, Gary R. Matyas, Nabila M. Wassef, Mangala Rao