Abstract: A joint between a fluid connector body and a plastic tube is formed at least in part by spin welding, wherein the portion of the connector which is configured to receive the tube defines inner and outer surfaces which engage the inner and outer surfaces of the mating tube to create redundant circumferentially continuous seals between the fluid passageway and the outside environment. The use of multi-layer co-extruded plastic tubing having intermediate or bonding layers is particularly advantageous inasmuch as separate inner and outer seals are established between the connector housing and the inner and outer tubing layers, respectively, to ensure that neither system fluids nor foreign contaminants are exposed to the intermediate tube layers, thereby preventing capillary adsorption or delamination.