Patents by Inventor Gary Schieven

Gary Schieven has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sting agonists for treating bladder cancer and solid tumors
    Patent number: 11883420
    Abstract: Methods for treating bladder cancer and solid tumors are disclosed. The methods include administering to a patient a compound of formula 1 Pharmaceutical compositions of compound 1 are also disclosed.
    Type: Grant
    Filed: June 8, 2021
    Date of Patent: January 30, 2024
    Assignee: VENENUM BIODESIGN, LLC
    Inventors: Brian F. McGuinness, Grant Gallagher, Michael S. McQueney, Rukiye Nazan Eraslan, Gary Schieven, Jason Trama, Axel Metzger, David J. Diller, David E. Kaelin
  • STING AGONISTS FOR TREATING BLADDER CANCER AND SOLID TUMORS
    Publication number: 20210290645
    Abstract: Methods for treating bladder cancer and solid tumors are disclosed. The methods include administering to a patient a compound of formula 1 Pharmaceutical compositions of compound 1 are also disclosed.
    Type: Application
    Filed: June 8, 2021
    Publication date: September 23, 2021
    Applicant: Venenum Biodesign, LLC
    Inventors: Brian F. McGUINNESS, Grant GALLAGHER, Michael S. McQUENEY, Rukiye NAZAN ERASLAN, Gary SCHIEVEN, Jason TRAMA, Axel METZGER, David J. DILLER, David E. KAELIN
  • Sting agonists for treating bladder cancer and solid tumors
    Patent number: 11110106
    Abstract: Methods for treating bladder cancer and solid tumors are disclosed. The methods include administering to a patient a compound of formula 1 Pharmaceutical compositions of compound 1 are also disclosed.
    Type: Grant
    Filed: November 12, 2020
    Date of Patent: September 7, 2021
    Assignee: VENENUM BIODESIGN, LLC
    Inventors: Brian F. McGuinness, Grant Gallagher, Michael S. McQueney, Rukiye Nazan Eraslan, Gary Schieven, Jason Trama, Venugopalareddy Bommireddy Venkata, Axel Metzger, David J. Diller, David E. Kaelin
  • Cyclic protein tyrosine kinase inhibitors
    Patent number: 7153856
    Abstract: Novel cyclic compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders.
    Type: Grant
    Filed: May 26, 2005
    Date of Patent: December 26, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Joel C. Barrish, John Wityak, Jagabandhu Das, Ping Chen, Derek J. Norris, Gary Schieven
  • Human phosphatase RET31, and variants thereof
    Publication number: 20060014180
    Abstract: The present invention provides novel polynucleotides encoding human phosphatase polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel human phosphatase polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly cardiovascular diseases and/or disorders. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: June 2, 2005
    Publication date: January 19, 2006
    Inventors: Donald Jackson, Chandra Ramanathan, John Feder, Gabe Mintier, Liana Lee, Thomas Nelson, Nathan Siemers, David Bol, Suzanne Suchard, Gary Schieven, Joshua Finger, C. Todderrud, Donna Bassolino, Stanley Krystek, Dana Banas, Patrick McAtee
  • Cyclic protein tyrosine kinase inhibitors
    Publication number: 20050288303
    Abstract: Novel cyclic compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders.
    Type: Application
    Filed: May 26, 2005
    Publication date: December 29, 2005
    Inventors: Joel Barrish, John Wityak, Jagabandhu Das, Ping Chen, Derek Norris, Gary Schieven
  • POLYNUCLEOTIDES ENCODING NOVEL HUMAN PHOSPHATASES
    Publication number: 20050130286
    Abstract: The present invention provides novel polynucleotides encoding human phosphatase polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel human phosphatase polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly cardiovascular diseases and/or disorders. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: December 20, 2001
    Publication date: June 16, 2005
    Inventors: Donald Jackson, Chandra Ramanathan, John Feder, Gabe Mintier, Liana Lee, Thomas Nelson, Nathan Siemers, David Bol, Suzanne Suchard, Gary Schieven, Joshua Finger, C. Todderrud, Donna Bassolino, Stanley Krystek, Dana Banas, Patrick McAtee
  • Methods of reducing ischemic injury
    Publication number: 20040110710
    Abstract: The present invention includes methods of reducing the activity, such as enzymatic activity and expression, of mitogen-activated protein kinase-activated protein kinase 2. The present invention further includes methods for identifying compounds useful for reducing such activity, and methods for reducing ischemic injury by the administration of such compounds.
    Type: Application
    Filed: August 21, 2003
    Publication date: June 10, 2004
    Inventors: Xinkang Wang, Gary Schieven, Giora Z. Feuerstein