Patents by Inventor Gary Silkstone

Gary Silkstone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12180266
    Abstract: The present invention relates to modified proteins e.g. oxygen-carrying proteins, with improved or enhanced, in comparison to a reference protein, reduction of a metal ion associated with the modified protein. The present invention also relates to methods of using such modified proteins and compositions comprising such proteins e.g. in therapy.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: December 31, 2024
    Assignee: University of Essex Enterprises Limited
    Inventors: Chris E. Cooper, Brandon Reeder, Gary Silkstone
  • Patent number: 11529421
    Abstract: Certain aspects of the present invention relate to modified hemoglobin proteins comprising at least one modification (e.g., at the thiol group of an exogenous amino acid residue) for homogenous conjugation of one or more polymeric moieties e.g. polyethylene glycol or derivatives thereof. Also included herein are methods of using such modified proteins and compositions comprising such proteins, e.g. in therapy.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: December 20, 2022
    Assignee: University of Essex Enterprises Limited
    Inventors: Chris E. Cooper, Brandon Reeder, Gary Silkstone
  • Publication number: 20210369851
    Abstract: Certain aspects of the present invention relate to modified proteins e.g. oxygen-carrying proteins, comprising at least one modification for homogenous conjugation of one or more polymeric moieties e.g. polyethylene glycol or derivatives thereof.
    Type: Application
    Filed: December 19, 2018
    Publication date: December 2, 2021
    Inventors: Chris E. Cooper, Brandon Reeder, Gary Silkstone
  • Publication number: 20200131247
    Abstract: The present invention relates to modified proteins e.g. oxygen-carrying proteins, with improved or enhanced, in comparison to a reference protein, reduction of a metal ion associated with the modified protein. The present invention also relates to methods of using such modified proteins and compositions comprising such proteins e.g. in therapy.
    Type: Application
    Filed: March 13, 2018
    Publication date: April 30, 2020
    Inventors: Chris E. Cooper, Brandon Reeder, Gary Silkstone