Patents by Inventor Gary T. Wang

Gary T. Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
    Patent number: 11897864
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
    Type: Grant
    Filed: October 7, 2022
    Date of Patent: February 13, 2024
    Assignees: AbbVie Inc., Genentech, Inc., The Walter and Eliza Hall Institute of Medical Research
    Inventors: Milan Bruncko, Hong Ding, George A. Doherty, Steven W. Elmore, Lisa A. Hasvold, Laura Hexamer, Aaron R. Kunzer, Xiaohong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao, Gary T. Wang, Le Wang, Xilu Wang, Michael D. Wendt, Robert Mantei, Todd M. Hansen
  • APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
    Publication number: 20240043404
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
    Type: Application
    Filed: September 6, 2023
    Publication date: February 8, 2024
    Applicants: AbbVie Inc., Genentech, Inc., The Walter and Eliza Hall Institute of Medical Research
    Inventors: Milan Bruncko, Hong Ding, George A. Doherty, Steven W. Elmore, Lisa A. Hasvold, Laura Hexamer, Aaron R. Kunzer, Xiaohong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao, Gary T. Wang, Le Wang, Xilu Wang, Michael D. Wendt, Robert Mantei, Todd M. Hansen
  • APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
    Publication number: 20230143532
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
    Type: Application
    Filed: October 7, 2022
    Publication date: May 11, 2023
    Applicants: AbbVie Inc., Genentech, Inc., The Walter and Eliza Hall Institute of Medical Research
    Inventors: Milan Bruncko, Hong Ding, George A. Doherty, Steven W. Elmore, Lisa A. Hasvold, Laura Hexamer, Aaron R. Kunzer, Xiaohong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao, Gary T. Wang, Le Wang, Xilu Wang, Michael D. Wendt, Robert Mantei, Todd M. Hansen
  • Methods of controlling pests using terpendoles
    Patent number: 11497214
    Abstract: The present invention is directed to a method of controlling a pest comprising applying an effective amount of one or more terpendoles to the pest or an area in need of pest control. The present invention is further directed to a method of controlling a pest comprising applying an effective amount of one or more compounds having the following chemical structure to the pest or an area in need of pest control.
    Type: Grant
    Filed: June 24, 2020
    Date of Patent: November 15, 2022
    Assignee: VALENT BIOSCIENCES LLC
    Inventors: Deanna Branscome, Daniel F. Heiman, Jose Maria Sanchez Lopez, Joseph H. Lustig, Gary T. Wang, Daniel C Leep
  • APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
    Publication number: 20220315555
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
    Type: Application
    Filed: November 3, 2021
    Publication date: October 6, 2022
    Applicants: AbbVie Inc., Genentech, Inc., The Walter and Eliza Hall Institute of Medical Research
    Inventors: Milan BRUNCKO, Hong DING, George A. DOHERTY, Steven W. ELMORE, Lisa A. HASVOLD, Laura HEXAMER, Aaron R. KUNZER, Xiaohong SONG, Andrew J. SOUERS, Gerard M. SULLIVAN, Zhi-Fu TAO, Gary T. WANG, Le WANG, Xilu WANG, Michael D. WENDT, Robert MANTEI, Todd M. HANSEN
  • APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
    Publication number: 20210221789
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
    Type: Application
    Filed: August 27, 2020
    Publication date: July 22, 2021
    Inventors: Milan Bruncko, Hong Ding, George A. Doherty, Steven W. Elmore, Lisa A. Hasvold, Laura Hexamer, Aaron R. Kunzer, Xiaohong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao, Gary T. Wang, Le Wang, Xilu Wang, Michael D. Wendt, Robert Mantei, Todd M. Hansen
  • Tolypocladium album strain
    Patent number: 10945443
    Abstract: A novel fungal strain of Tolypocladium album (synonym Chaunopycnis alba) is disclosed that has enhanced toxicity against insects and mites. This novel Tolypocladium album strain is capable of producing terpendoles A, C, I, J, K, N, O and P through fermentation and does not produce nalanthalide.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: March 16, 2021
    Assignee: VALENT BIOSCIENCES LLC
    Inventors: Maria de los Angeles Vinuesa Navarro, Jose Maria Sanchez Lopez, Deanna Branscome, Emily E. Brazil, Rebecca Dickenson, Daniel F. Heiman, Gary T. Wang, Zuoxing Zheng, Daniel C Leep
  • METHODS OF CONTROLLING PESTS USING TERPENDOLES
    Publication number: 20200352169
    Abstract: The present invention is directed to a method of controlling a pest comprising applying an effective amount of one or more terpendoles to the pest or an area in need of pest control. The present invention is further directed to a method of controlling a pest comprising applying an effective amount of one or more compounds having the following chemical structure to the pest or an area in need of pest control.
    Type: Application
    Filed: June 24, 2020
    Publication date: November 12, 2020
    Inventors: Deanna Branscome, Daniel F. Heiman, Jose Maria Sanchez Lopez, Joseph H. Lustig, Gary T. Wang
  • Methods of controlling pests using terpendoles
    Patent number: 10729135
    Abstract: The present invention is directed to a method of controlling a pest comprising applying an effective amount of one or more terpendoles to the pest or an area in need of pest control. The present invention is further directed to a method of controlling a pest comprising applying an effective amount of one or more compounds having the following chemical structure to the pest or an area in need of pest control.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: August 4, 2020
    Assignee: VALENT BIOSCIENCES LLC
    Inventors: Deanna Branscome, Daniel F. Heiman, Jose Maria Sanchez Lopez, Joseph H. Lustig, Gary T. Wang
  • APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
    Publication number: 20200231566
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
    Type: Application
    Filed: August 30, 2019
    Publication date: July 23, 2020
    Inventors: Milan Bruncko, Hong Ding, George A. Doherty, Steven W. Elmore, Lisa A. Hasvold, Laura Hexamer, Aaron R. Kunzer, Xiaohong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao, Gary T. Wang, Le Wang, Xilu Wang, Michael D. Wendt, Robert Mantei, Todd M. Hansen
  • (S)-abscisic acid derivatives for improving plant stress tolerance
    Patent number: 10314307
    Abstract: The present invention is directed to the treatment of crop plants with 3?-methyl-(S)-abscisic acid, 3?-propargyl-(S)-abscisic acid, and/or salts thereof in order to improve the plants' environmental stress tolerance.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: June 11, 2019
    Assignee: VALENT BIOSCIENCES LLC
    Inventors: Franklin Paul Silverman, Gary T. Wang, Kimberly Ann Falco, Derek D. Woolard, Dale O. Wilson, Jr., Daniel C. Leep, Gregory D. Venburg
  • 3?-substituted-abscisic acid derivatives
    Patent number: 10299476
    Abstract: The invention relates to a novel class of (S)-3?-substituted-abscisic acid derivatives and (±)-3?-substituted-abscisic acid derivatives, and methods of synthesizing the derivatives.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: May 28, 2019
    Assignee: VALENT BIOSCIENCES LLC
    Inventors: Gary T. Wang, Daniel F. Heiman, Gregory D. Venburg, Eiki Nagano, Marci Surpin, Joseph H. Lustig
  • APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
    Publication number: 20190119247
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
    Type: Application
    Filed: May 30, 2018
    Publication date: April 25, 2019
    Inventors: Milan Bruncko, Hong Ding, George A. Doherty, Steven W. Elmore, Lisa A. Hasvold, Laura Hexamer, Aaron R. Kunzer, Xiaohong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao, Gary T. Wang, Le Wang, Xilu Wang, Michael D. Wendt, Robert Mantei, Todd M. Hansen
  • METHODS OF CONTROLLING PESTS USING TERPENDOLES
    Publication number: 20190098900
    Abstract: The present invention is directed to a method of controlling a pest comprising applying an effective amount of one or more terpendoles to the pest or an area in need of pest control. The present invention is further directed to a method of controlling a pest comprising applying an effective amount of one or more compounds having the following chemical structure to the pest or an area in need of pest control.
    Type: Application
    Filed: September 25, 2018
    Publication date: April 4, 2019
    Inventors: Deanna Branscome, Daniel F. Heiman, Jose Maria Sanchez Lopez, Joseph H. Lustig, Gary T. Wang
  • NOVEL TOLYPOCLADIUM ALBUM STRAIN
    Publication number: 20190098904
    Abstract: A novel fungal strain of Tolypocladium album (synonym Chaunopycnis alba) is disclosed that has enhanced toxicity against insects and mites. This novel Tolypocladium album strain is capable of producing terpendoles A, C, I, J, K, N, O and P through fermentation and does not produce nalanthalide.
    Type: Application
    Filed: September 25, 2018
    Publication date: April 4, 2019
    Inventors: Maria de los Angeles Vinuesa Navarro, Jose Maria Sanchez Lopez, Deanna Branscome, Emily E. Brazil, Rebecca Dickenson, Daniel F. Heiman, Gary T. Wang, Zuoxing Zheng
  • 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID POLYMORPHS
    Publication number: 20180282260
    Abstract: The present invention is directed to 1-aminocyclopropane-1-carboxylic acid polymorphs and agricultural compositions thereof.
    Type: Application
    Filed: March 29, 2018
    Publication date: October 4, 2018
    Inventors: Mitsunobu Kawamura, Daniel F. Heiman, Kosuke Takebayashi, Gary T. Wang
  • APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
    Publication number: 20180251426
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
    Type: Application
    Filed: October 13, 2017
    Publication date: September 6, 2018
    Inventors: Milan Bruncko, Yujia Dai, Hong Ding, George A. Doherty, Steven W. Elmore, Lisa Hasvold, Laura Hexamer, Aaron R. Kunzer, Robert A. Mantei, Chang H. Park, Cheol-Min Park, Andrew M. Petros, Xiaohong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao, Gary T. Wang, Le Wang, Xilu Wang, Michael D. Wendt, William J. McClellan
  • (S)-abscisic acid derivatives for enhanced grape coloration
    Patent number: 9877480
    Abstract: The present invention is directed to the treatment of grapes with 3?-methyl-(S)-abscisic acid, 3?-propargyl-(S)-abscisic acid, and/or salts thereof in order to enhance the color of the grapes.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: January 30, 2018
    Assignee: Valent Biosciences LLC
    Inventors: Derek D. Woolard, Gary T. Wang, Rick Hopkins, Daniel C. Leep, Gregory D. Venburg
  • (S)-abscisic acid derivatives for thinning
    Patent number: 9872492
    Abstract: The present invention is directed to the treatment of apple trees, peach trees, and grape vines with 3?-methyl-(S)-abscisic acid, 3?-propargyl-(S)-abscisic acid, and/or salts thereof in order to reduce the number of fruits on the trees or vines that grow to maturity.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: January 23, 2018
    Assignee: Valent Biosciences LLC
    Inventors: Derek D. Woolard, Gary T. Wang, Daniel C. Leep, Gregory D. Venburg
  • 3?-SUBSTITUTED-ABSCISIC ACID DERIVATIVES
    Publication number: 20170360037
    Abstract: The invention relates to a novel class of (S)-3?-substituted-abscisic acid derivatives and (±)-3?-substituted-abscisic acid derivatives, and methods of synthesizing the derivatives.
    Type: Application
    Filed: September 5, 2017
    Publication date: December 21, 2017
    Inventors: Gary T. Wang, Daniel F. Heiman, Gregory D. Venburg, Eiki Nagano, Marci Surpin, Joseph H. Lustig