Abstract: A dispenser for the delivery of a droplet of a liquid comprises a housing which defines an outlet orifice, a tip seal, biased against the housing to seal the outlet orifice, and a dosing pump for pumping a liquid to the outlet nozzle. The dispenser further comprises an actuation pump configured to provide a hydraulic opening force to the tip seal for opening of the outlet orifice. Preferably the actuation pump is configured to operate at a higher pressure than the dosing pump.

Abstract: A guide device for assisting the application of a liquid from a dispenser to the eye of a subject has a mount to hold the liquid dispenser in the guide device, a rest to align the guide device with the subject head, and an indicator, selectively visible to indicate when the guide device is tilted at or beyond a minimum guide angle. Preferably, the indicator is selectively visible to indicate when the guide device is tilted at, or between, the minimum guide angle and a maximum guide angle. Said minimum guide angle corresponds with a minimum predetermined tilt of the subject head suitable for delivery of the liquid from the dispenser. The maximum guide angle corresponds with a maximum predetermined tilt of the subject head suitable for delivery of the liquid.

Abstract: A dispenser for the delivery of a droplet of a liquid comprises a housing which defines an outlet orifice, a tip seal, biased against the housing to seal the outlet orifice, and a dosing pump for pumping a liquid to the outlet nozzle. The dispenser further comprises an actuation pump configured to provide a hydraulic opening force to the tip seal for opening of the outlet orifice. Preferably the actuation pump is configured to operate at a higher pressure than the dosing pump.

Abstract: One aspect provides a drug dispenser device comprising a housing; extending from the housing, an outlet for insertion into a body cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the container, a container collar connected to the discharge device; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element including an actuating portion; provided to the housing, at least one finger operable member moveable to apply an actuating force to the actuating portion of the transfer element to move the transfer element from a

Abstract: There is provided a drug dispenser device comprising a housing; extending from the housing, an outlet for insertion into a body cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the drug discharge device, a container collar; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element, the transfer element including an actuating portion; provided to the housing, at least one finger operable member moveable to apply a force to the actuating portion of the transfer element to move the transfer element along the longitudinal axis in a first direction; linking the container collar with the transfer element, a biasing mechanism to store biasing ene

Abstract: An actuator for an inhaler for delivering medicament by inhalation, comprising: a housing for receiving a canister which comprises a body which includes a base and a head and defines a chamber containing medicament, and a valve stem which extends from the body and from which medicament is in use delivered on actuation of the canister; an outlet through which a user in use inhales; and a nozzle assembly which provides for delivery of medicament through the outlet, wherein the nozzle assembly comprises a nozzle block which receives the valve stem of the canister and, as a separately-formed component, a nozzle outlet which is fluidly connected to the nozzle block and includes an outlet orifice from which medicament is in use delivered.

Abstract: A dose counter for use with a medicament dispenser which comprises a ratchet; a first count wheel arranged to rotate about a first axis of rotation, the first count wheel including one or more ratchet drive receipt elements arranged thereon for receipt of drive from the ratchet to rotate the first count wheel about the first axis of rotation; a second count wheel arranged to rotate about the first axis of rotation, the second count wheel including a set of teeth arranged annularly thereon; and a kick wheel arranged to rotate about a second axis of rotation offset from the first axis of rotation, the kick wheel including a set of kick teeth arranged annularly thereon and in meshed relationship with the teeth of the second count wheel such that rotary motion of the kick wheel results in rotary motion of the second count wheel is described.

Abstract: An actuator for an inhaler for delivering drug by inhalation, comprising: a housing for receiving a canister which comprises a body which includes a base and a head and defines a chamber for containing drug, and a valve stem which extends from the body and from which drug is in use delivered on actuation of the canister; and an outlet through which a user in use inhales, wherein the outlet has a substantially closed rear section which partitions the outlet from the housing, such that, on inhalation through the outlet, an air flow is drawn substantially only from an outer peripheral surface of the outlet.

Abstract: One aspect provides a drug dispenser device comprising a housing; extending from the housing, an outlet for insertion into a body cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the container, a container collar connected to the discharge device; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element including an actuating portion; provided to the housing, at least one finger operable member moveable to apply an actuating force to the actuating portion of the transfer clement to move the transfer element from a

Abstract: An actuator for an inhaler for delivering drug by inhalation, comprising: a housing for receiving a canister which comprises a body which includes a base and a head and defines a chamber for containing drug, and a valve stem which extends from the body and from which drug is in use delivered on actuation of the canister; an outlet through which a user in use inhales; and a nozzle which provides for delivery of drug through the outlet; wherein at least a rear section of the outlet has an increasing internal dimension in a direction away from the nozzle.

Abstract: An actuator for an inhaler for delivering medicament by inhalation, comprising: a housing for receiving a canister which comprises a body which includes a base and a head and defines a chamber containing medicament, and a valve stem which extends from the body and from which medicament is in use delivered on actuation of the canister; an outlet through which a user in use inhales; and a nozzle assembly which provides for delivery of medicament through the outlet, wherein the nozzle assembly comprises a nozzle block which receives the valve stem of the canister and, as a separately-formed component, a nozzle outlet which is fluidly connected to the nozzle block and includes an outlet orifice from which medicament is in use delivered.

Abstract: An actuator for an inhaler for delivering drug by inhalation, comprising: a housing for receiving a canister which comprises a body which includes a base and a head and defines a chamber for containing drug, and a valve stem which extends from the body and from which drug is in use delivered on actuation of the canister; an outlet through which a user in use inhales; and a nozzle which provides for delivery of drug through the outlet; wherein the outlet includes at least one air flow path which provides for a substantially annular air flow at an inner peripheral surface of the outlet on inhalation by the user through the outlet, such as to provide a sheathing air flow to an aerosol spray when delivered from the nozzle.

Abstract: There is provided a drug dispenser device comprising a housing; extending from the housing, an outlet for insertion into a body cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the drug discharge device, a container collar; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element, the transfer element including an actuating portion; provided to the housing, at least one finger operable member moveable to apply a force to the actuating portion of the transfer element to move the transfer element along the longitudinal axis in a first direction; linking the container collar with the transfer element, a biasing mechanism to store biasing ene

Abstract: A dose counter for use with a medicament dispenser which comprises a ratchet; a first count wheel arranged to rotate about a first axis of rotation, the first count wheel including one or more ratchet drive receipt elements arranged thereon for receipt of drive from the ratchet to rotate the first count wheel about the first axis of rotation; a second count wheel arranged to rotate about the first axis of rotation, the second count wheel including a set of teeth arranged annularly thereon; and a kick wheel arranged to rotate about a second axis of rotation offset from the first axis of rotation, the kick wheel including a set of kick teeth arranged annularly thereon and in meshed relationship with the teeth of the second count wheel such that rotary motion of the kick wheel results in rotary motion of the second count wheel is described.