Abstract: An atherectomy system includes an atherectomy burr and a driveshaft adapted to carry the atherectomy burr. The atherectomy burr includes a cavity that extends distally into the atherectomy burr from a proximal end region. The driveshaft extends into the cavity. An adhesive is within the cavity to secure the atherectomy burr to the driveshaft. At least one of the cavity and/or the driveshaft are adapted to align a centerline of the atherectomy burr with a centerline of the driveshaft.

Abstract: An atherectomy system includes a drive mechanism adapted to rotatably actuate an atherectomy burr and a controller that is adapted to regulate operation of the drive mechanism. The controller is adapted to calculate an estimated load torque at the atherectomy burr based upon at least one of an angular velocity of the atherectomy system and an angular acceleration of the atherectomy system. The controller is further adapted to stop or reverse the drive mechanism when the estimated load torque at the atherectomy burr exceeds a torque threshold.

Abstract: The present disclosure pertains to injectable shear-thinning compositions that comprise (a) one or more types of fibrous proteins, (b) one or more types of silicate microparticles, (c) one or more types of radiopaque additives, (d) one or more types of cryoprotectants, and (e) water. Other aspects of the present disclosure pertain to kits that contains such compositions and medical procedures that comprise administering such compositions to a patient.

Abstract: An atherectomy system includes an atherectomy burr having one or more blood flow enhancement features that permit an increased level of blood flow past the burr relative to a blood flow that would result absent the one or more flow enhancement features. A drive mechanism is adapted to rotatably actuate the atherectomy burr.

Abstract: In some embodiments, the present disclosure pertains to an injectable shear-thinning composition that comprises (a) one or more types of polymers, (b) one or more types of microparticles and (c) water. In some embodiments, the present disclosure pertains to a kit that comprises (a) one or more containers that contain an injectable shear-thinning composition that comprises one or more types of polymers, one or more types of microparticles and water and (b) a delivery device. In some embodiments, the present disclosure pertains to a medical procedure comprising administering to a subject an injectable shear-thinning composition that comprises one or more types of polymers, one or more types of microparticles and water.

Abstract: Medical device systems as well as methods for making and using medical device systems are disclosed. An example medical device system may include an advancer including a drive mechanism. A sleeve may be secured to the drive mechanism. A drive shaft may extend through the sleeve. The drive shaft may have a proximal end region secured to the drive mechanism and a distal end region. A rotational device may be coupled to the distal end region of the drive shaft.

Abstract: An atherectomy system includes an atherectomy burr having one or more blood flow enhancement features that permit an increased level of blood flow past the burr relative to a blood flow that would result absent the one or more flow enhancement features. A drive mechanism is adapted to rotatably actuate the atherectomy burr.

Abstract: An atherectomy system includes a drive mechanism adapted to rotatably actuate an atherectomy burr and a controller that is adapted to regulate operation of the drive mechanism. The controller is adapted to calculate an estimated load torque at the atherectomy burr based upon at least one of an angular velocity of the atherectomy system and an angular acceleration of the atherectomy system. The controller is further adapted to stop or reverse the drive mechanism when the estimated load torque at the atherectomy burr exceeds a torque threshold.