Patents by Inventor Gary Tollefson

Gary Tollefson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220257591
    Abstract: Disclosed are methods and compositions for treating visceral fat conditions and/or metabolic syndrome using combinations of naltrexone and bupropion.
    Type: Application
    Filed: May 9, 2022
    Publication date: August 18, 2022
    Applicant: Nalpropioin Pharmaceuticals LLC
    Inventor: Gary Tollefson
  • Patent number: 11033543
    Abstract: Disclosed are methods of providing weight loss therapy, particularly for patients suffering from major depression.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: June 15, 2021
    Assignee: Nalpropion Pharmaceuticals LLC
    Inventors: Eduardo Dunayevich, Gary Tollefson
  • Publication number: 20190282503
    Abstract: Methods and systems for administration of pharmaceuticals using a unit dosage package that includes a first unit dosage that has a first drug and a second drug, a second unit dosage that has the first drug and the second drug, where the second unit dosage includes a different amount of the second drug than the first unit dosage and a unit dosage package is configured to hold the first unit dosage and the second unit dosage. In preferred embodiments the methods and systems are used for administration of weight loss medications.
    Type: Application
    Filed: May 31, 2019
    Publication date: September 19, 2019
    Inventors: Anthony A. McKinney, Gary Tollefson, Eckard Weber, Rick Soltero
  • Publication number: 20190183883
    Abstract: A sustained-release oral dosage form of naltrexone or a pharmaceutically acceptable salt thereof is provided. The oral dosage form may be administered with another compound. Administration of the oral dosage form may reduce a side effect, which may be a side effect at least partially attributable to a weight-loss treatment. The oral dosage form may be administered to treat a weight-loss condition.
    Type: Application
    Filed: February 25, 2019
    Publication date: June 20, 2019
    Inventors: Anthony A. McKinney, Gary Tollefson, Richard Soltero, Thea Elise Dunzo
  • Patent number: 10307376
    Abstract: Methods and systems for administration of pharmaceuticals using a unit dosage package that includes a first unit dosage that has a first drug and a second drug, a second unit dosage that has the first drug and the second drug, where the second unit dosage includes a different amount of the second drug than the first unit dosage and a unit dosage package is configured to hold the first unit dosage and the second unit dosage. In preferred embodiments the methods and systems are used for administration of weight loss medications.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: June 4, 2019
    Assignee: Nalpropion Pharmaceuticals, Inc.
    Inventors: Anthony A. McKinney, Gary Tollefson, Eckard Weber, Rick Soltero
  • Publication number: 20180360760
    Abstract: Methods and systems for administration of pharmaceuticals using a unit dosage package that includes a first unit dosage that has a first drug and a second drug, a second unit dosage that has the first drug and the second drug, where the second unit dosage includes a different amount of the second drug than the first unit dosage and a unit dosage package is configured to hold the first unit dosage and the second unit dosage. In preferred embodiments the methods and systems are used for administration of weight loss medications.
    Type: Application
    Filed: August 13, 2018
    Publication date: December 20, 2018
    Inventors: Anthony A. McKinney, Gary Tollefson, Eckard Weber, Rick Soltero
  • Publication number: 20170312269
    Abstract: Disclosed are compositions for reducing food cravings, comprising a first compound and a second compound, where the first compound is an opioid antagonist and the second compound is an ?-MSH agonist. Also disclosed are methods of reducing food cravings, comprising identifying an individual in need thereof and treating that individual to antagonize opioid receptor activity and to enhance ?-MSH activity.
    Type: Application
    Filed: January 20, 2017
    Publication date: November 2, 2017
    Inventors: Anthony A. McKinney, Gary Tollefson, Michael A. Cowley
  • Publication number: 20160354348
    Abstract: Pharmaceutical formulations comprise sustained-release zonisamide. Methods of preparing such pharmaceutical formulations involve intermixing zonisamide with a suitable excipient configured to control the dissolution profile of the zonisamide. Methods of treatment involve administering the pharmaceutical formulations to patients in need of such treatment.
    Type: Application
    Filed: January 22, 2016
    Publication date: December 8, 2016
    Inventors: Anthony A. McKinney, Gary Tollefson, Simon Kwok-Pan Yau, Ronald S. Vladyka, Rick Soltero
  • Patent number: 9457005
    Abstract: Methods and compositions for treating a blood glucose condition involve identifying a suitable subject and administering an effective amount of a composition that contains one or more of an opioid antagonist, an anticonvulsant, and a psychotherapeutic agent. The compositions can include insulin. In some embodiments, such methods and compositions can be used to modulate a blood glucose level. In preferred embodiments, such methods and compositions are useful for increasing a subject's sensitivity to insulin.
    Type: Grant
    Filed: July 8, 2014
    Date of Patent: October 4, 2016
    Assignee: OREXIGEN THERAPEUTICS, INC.
    Inventors: Michael A. Cowley, Anthony A. McKinney, Gary Tollefson
  • Publication number: 20160193152
    Abstract: Methods and systems for administration of pharmaceuticals using a unit dosage package that includes a first unit dosage that has a first drug and a second drug, a second unit dosage that has the first drug and the second drug, where the second unit dosage includes a different amount of the second drug than the first unit dosage and a unit dosage package is configured to hold the first unit dosage and the second unit dosage. In preferred embodiments the methods and systems are used for administration of weight loss medications.
    Type: Application
    Filed: September 3, 2015
    Publication date: July 7, 2016
    Inventors: Anthony A. McKinney, Gary Tollefson, Eckard Weber, Rick Soltero
  • Patent number: 9248123
    Abstract: Disclosed are methods of providing weight loss therapy, particularly for patients suffering from major depression.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: February 2, 2016
    Assignee: Orexigen Therapeutics, Inc.
    Inventors: Eduardo Dunayevich, Gary Tollefson, David Dewitt
  • Patent number: 9125868
    Abstract: Methods and systems for administration of pharmaceuticals using a unit dosage package that includes a first unit dosage that has a first drug and a second drug, a second unit dosage that has the first drug and the second drug, where the second unit dosage includes a different amount of the second drug than the first unit dosage and a unit dosage package is configured to hold the first unit dosage and the second unit dosage. In preferred embodiments the methods and systems are used for administration of weight loss medications.
    Type: Grant
    Filed: March 20, 2014
    Date of Patent: September 8, 2015
    Assignee: OREXIGEN THERAPEUTICS, INC.
    Inventors: Anthony A. McKinney, Gary Tollefson, Eckard Weber, Rick Soltero
  • Publication number: 20150164806
    Abstract: In one embodiment a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers, the intermediate layer configured to dissolve in vivo to thereby leave the two or more pharmaceutical layers substantially intact. In one embodiment, an active pharmaceutical ingredient in at least one of the pharmaceutical layers is selected from bupropion, zonisamide, naltrexone, topiramate, phentermine, metformin, olanzapine and fluoxetine.
    Type: Application
    Filed: November 14, 2014
    Publication date: June 18, 2015
    Inventors: Anthony A. McKinney, Gary Tollefson, Eckard Weber, Rick Soltero
  • Publication number: 20140323399
    Abstract: Methods and compositions for treating a blood glucose condition involve identifying a suitable subject and administering an effective amount of a composition that contains one or more of an opioid antagonist, an anticonvulsant, and a psychotherapeutic agent. The compositions can include insulin. In some embodiments, such methods and compositions can be used to modulate a blood glucose level. In preferred embodiments, such methods and compositions are useful for increasing a subject's sensitivity to insulin.
    Type: Application
    Filed: July 8, 2014
    Publication date: October 30, 2014
    Inventors: Michael A. Cowley, Anthony A. McKinney, Gary Tollefson
  • Publication number: 20140322318
    Abstract: Methods and systems for administration of pharmaceuticals using a unit dosage package that includes a first unit dosage that has a first drug and a second drug, a second unit dosage that has the first drug and the second drug, where the second unit dosage includes a different amount of the second drug than the first unit dosage and a unit dosage package is configured to hold the first unit dosage and the second unit dosage. In preferred embodiments the methods and systems are used for administration of weight loss medications.
    Type: Application
    Filed: March 20, 2014
    Publication date: October 30, 2014
    Inventors: Anthony A. McKinney, Gary Tollefson, Eckard Weber, Rick Soltero
  • Publication number: 20140309252
    Abstract: Disclosed are compositions for reducing food cravings, comprising a first compound and a second compound, where the first compound is an opioid antagonist and the second compound is an ?-MSH agonist. Also disclosed are methods of reducing food cravings, comprising identifying an individual in need thereof and treating that individual to antagonize opioid receptor activity and to enhance ?-MSH activity.
    Type: Application
    Filed: March 12, 2014
    Publication date: October 16, 2014
    Inventors: Anthony A. McKinney, Gary Tollefson, Michael A. Cowley
  • Patent number: 8815889
    Abstract: Methods and compositions for treating a blood glucose condition involve identifying a suitable subject and administering an effective amount of a composition that contains one or more of an opioid antagonist, an anticonvulsant, and a psychotherapeutic agent. The compositions can include insulin. In some embodiments, such methods and compositions can be used to modulate a blood glucose level. In preferred embodiments, such methods and compositions are useful for increasing a subject's sensitivity to insulin.
    Type: Grant
    Filed: November 21, 2006
    Date of Patent: August 26, 2014
    Assignee: Orexigen Therapeutics, Inc.
    Inventors: Michael A. Cowley, Anthony A. McKinney, Gary Tollefson
  • Patent number: 8722085
    Abstract: Methods and systems for administration of pharmaceuticals using a unit dosage package that includes a first unit dosage that has a first drug and a second drug, a second unit dosage that has the first drug and the second drug, where the second unit dosage includes a different amount of the second drug than the first unit dosage and a unit dosage package is configured to hold the first unit dosage and the second unit dosage. In preferred embodiments the methods and systems are used for administration of weight loss medications.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: May 13, 2014
    Assignee: Orexigen Therapeutics, Inc.
    Inventors: Anthony McKinney, Gary Tollefson, Eckard Weber, Rick Soltero
  • Publication number: 20140080857
    Abstract: Pharmaceutical formulations comprise sustained-release zonisamide. Methods of preparing such pharmaceutical formulations involve intermixing zonisamide with a suitable excipient configured to control the dissolution profile of the zonisamide. Methods of treatment involve administering the pharmaceutical formulations to patients in need of such treatment.
    Type: Application
    Filed: August 13, 2013
    Publication date: March 20, 2014
    Applicant: Orexigen Therapeutics, Inc.
    Inventors: Anthony A. McKinney, Gary Tollefson, Simon Kwok-Pan Yau, Ronald S. Vladyka, Rick Soltero
  • Patent number: 8318788
    Abstract: In one embodiment a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers, the intermediate layer configured to dissolve in vivo to thereby leave the two or more pharmaceutical layers substantially intact. In one embodiment, an active pharmaceutical ingredient in at least one of the pharmaceutical layers is selected from bupropion, zonisamide, naltrexone, topiramate, phentermine, metformin, olanzapine and fluoxetine.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: November 27, 2012
    Assignee: Orexigen Therapeutics, Inc.
    Inventors: Anthony McKinney, Gary Tollefson, Eckard Weber, Rick Soltero