Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

Abstract: A liquefied-gas aerosol dusting composition is disclosed for preventing inhalation abuse incidents. The composition comprises at least one liquefied gas and denatonium benzoate, wherein the concentration of said denatonium benzoate in said aerosol dusting composition ranges from about 5 ppm to about 50 ppm.

Abstract: A liquefied-gas aerosol dusting composition is disclosed for preventing inhalation abuse incidents. The composition comprises at least one liquefied gas and denatonium benzoate, wherein the concentration of said denatonium benzoate in said aerosol dusting composition ranges from about 5 ppm to about 50 ppm.

Abstract: A method and system for in vivo dermal absorption testing of a laboratory animal uses a mask and harness for protecting the respiratory tract of the animal when the animal housed within a sealed chamber with a hazardous test vapor introduced in the chamber. Because of the difficulty of getting a good seal with a protective mask on a laboratory animal, this system is designed with an air leak from inside the mask into the chamber. To ensure that the test vapor does not infiltrate the mask nor leak from the chamber, the vapor is maintained at a negative pressure within the chamber as compared to the external atmospheric pressure and air is supplied to the mask for the animal to breathe at a positive pressure and at a greater rate than that needed by the animal.