Patents by Inventor Gary W. Litman

Gary W. Litman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIVM (BASIC, IMMUNOGLOBULIN-LIKE VARIABLE MOTIF-CONTAINING) GENE, TRANSCRIPTIONAL PRODUCTS, AND USES THEREOF
    Publication number: 20090232824
    Abstract: The subject invention provides polynucleotide sequences, designated BIVM, and transcriptional/translational products obtained from the polynucleotide sequences of the invention. The subject invention also provides polynucleotide and polypeptide sequences provided by SEQ ID NOs: 1-28. Also provided are methods of detecting the presence of BIVM nucleic acids or polypeptides in samples suspected of containing BIVM genes, BIVM transcriptional products, or BIVM translational products. These methods are also useful for the detection of BIVM orthologs. Other embodiments provide polypeptide and/or nucleic acid vaccines for the induction of an immune response to in an individual. Kits for detecting the presence of BIVM genes, orthologs thereof, BIVM polypeptides, or BIVM transcriptional products are also provided.
    Type: Application
    Filed: April 15, 2009
    Publication date: September 17, 2009
    Applicant: University of South Florida
    Inventors: GARY W. LITMAN, Noel A. Hawke, Jeffrey A. Yoder, Donna D. Eason
  • BIVM (basic, immunoglobulin-like variable motif-containing) gene, transcriptional products, and uses thereof
    Patent number: 7553491
    Abstract: The subject invention provides polynucleotide sequences, designated BIVM, and transcriptional/translational products obtained from the polynucleotide sequences of the invention. The subject invention also provides polynucleotide and polypeptide sequences provided by SEQ ID NOs:1-28. Also provided are methods of detecting the presence of BIVM nucleic acids or polypeptides in samples suspected of containing BIVM genes, BIVM transcriptional products, or BIVM translational products. These methods are also useful for the detection of BIVM orthologs. Other embodiments provide polypeptide and/or nucleic acid vaccines for the induction of an immune response to in an individual. Kits for detecting the presence of BIVM genes, orthologs thereof, BIVM polypeptides, or BIVM transcriptional products are also provided.
    Type: Grant
    Filed: May 2, 2006
    Date of Patent: June 30, 2009
    Assignee: University of South Florida
    Inventors: Gary W. Litman, Noel A. Hawke, Jeffrey A. Yoder, Donna D. Eason
  • Vector system for selection of genes encoding secreted proteins and membrane-bound proteins
    Patent number: 7112434
    Abstract: The subject invention concerns novel vectors for the rapid and robust selection for cDNA sequences that encode secreted or membrane-bound proteins. The invention also pertains to methods for cloning secreted or membrane-bound proteins, including proteins encoded by novel members of gene families.
    Type: Grant
    Filed: May 2, 2002
    Date of Patent: September 26, 2006
    Assignee: University of South Florida
    Inventors: John P. Cannon, Robert N. Haire, Gary W. Litman
  • BIVM (basic, immunoglobulin-like variable motif-containing) gene, transcriptional products, and uses thereof
    Patent number: 7038030
    Abstract: The subject invention provides polynucleotide sequences, designated BIVM, and transcriptional/translational products obtained from the polynucleotide sequences of the invention. The subject invention also provides polynucleotide and polypeptide sequences provided by SEQ ID NOs:1–28. Also provided are methods of detecting the presence of BIVM nucleic acids or polypeptides in samples suspected of containing BIVM genes, BIVM transcriptional products, or BIVM translational products. These methods are also useful for the detection of BIVM orthologs. Other embodiments provide polypeptide and/or nucleic acid vaccines for the induction of an immune response to in an individual. Kits for detecting the presence of BIVM genes, orthologs thereof, BIVM polypeptides, or BIVM transcriptional products are also provided.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: May 2, 2006
    Assignee: University of South Florida
    Inventors: Gary W. Litman, Noel A. Hawke, Jeffrey A. Yoder, Donna D. Eason
  • BIVM (basic, immunoglobulin-like variable motif-containing) gene, transcriptional products, and uses thereof
    Publication number: 20040002102
    Abstract: The subject invention provides polynucleotide sequences, designated BIVM, and transcriptional/translation products obtained from the polynucleotide sequences of the invention. The subject invention also provides polynucleotide and polypeptide sequences provided by SEQ ID NOs:1-28. Also provided are methods of detecting the presence of BIVM nucleic acids or polypeptides in samples suspected of containing BIVM genes, BIVM transcriptional products, or BIVM translational products. These methods are also useful for the detection of BIVM orthologs. Other embodiments provide polypeptide and/or nucleic acid vaccines for the induction of an immune response to in an individual. Kits for detecting the presence of BIVM genes, orthologs thereof, BIVM polypeptides, or BIVM transcriptional products are also provided.
    Type: Application
    Filed: April 16, 2003
    Publication date: January 1, 2004
    Applicant: University of South Florida
    Inventors: Gary W. Litman, Noel A. Hawke, Jeffrey A. Yoder, Donna D. Eason
  • Vector system for selection of genes encoding secreted proteins and membrane-bound proteins
    Publication number: 20030148299
    Abstract: The subject invention concerns novel vectors for the rapid and robust selection for cDNA sequences that encode secreted or membrane-bound proteins. The invention also pertains to methods for cloning secreted or membrane-bound proteins, including proteins encoded by novel members of gene families.
    Type: Application
    Filed: May 2, 2002
    Publication date: August 7, 2003
    Inventors: John P. Cannon, Robert N. Haire, Gary W. Litman
  • DNA vector for determining the presence of out-of-reading-frame mutations
    Patent number: 6284496
    Abstract: A DNA expression vector for positively selecting in-frame or out-of-reading-frame mutations in DNA sequences to be tested comprising a promotor operatively linked to an expressible reporter gene through a linkage sequence is disclosed. The linkage sequence includes at least two restriction sites and an engineered frameshift mutation. In an embodiment the frameshift is established by complementary sequences SEQ ID Nos:1 and 2. The expressible reporter gene is expressed as a fusion product including a green fluorescent protein and the promoter can be lacZ and inducible in E. coli.
    Type: Grant
    Filed: January 2, 1998
    Date of Patent: September 4, 2001
    Assignee: University of South Florida
    Inventors: Gary W. Litman, Noel A. Hawke, Robert N. Haire, Scott J. Strong