Abstract: The embodiments herein generally relate to systems, methods, and devices, including prosthetic capsular devices configured to be inserted in a natural capsular bag of an eye, the prosthetic capsular device comprising: a housing structure comprising an anterior portion and a posterior portion, an interior cavity, a groove formed along the circumference of the interior cavity, and a drug delivery device having a ring or an arc configuration, wherein the drug delivery device is held in place within the groove within the interior cavity of the housing structure.

Abstract: Disclosed is an enteric coated bead comprising Ixabepilone, a compound having a structure Also disclosed is a capsule comprising a multitude of the enteric coated beads. Further, a method of preparing the enteric coated bead and a method of treating cancer or other proliferative diseases using the enteric coated bead are disclosed.

Abstract: Disclosed is an enteric coated bead comprising at least one epothilone or epothilone analog; and a capsule comprising a multitude of the enteric coated beads. Also disclosed are a method of preparing the enteric coated bead and a method of treating cancer or other proliferative diseases using the enteric coated bead.