Abstract: The present invention provides a suppository applicator for use in the application of a suppository. A suppository applicator consists of a cylinder formed with a longitudinal bore, a plunger slidingly disposed in the longitudinal bore such that the relative axial movement of the plunger in the bore causes a suppository to exit the bore. A first flange is disposed on the cylinder for providing a grip for assisting in the handling of the applicator. A second flange is disposed on the cylinder for limiting the depth of insertion of the applicator cylinder into a body cavity. A second flange is slidingly disposed on the cylinder in one embodiment. A second flange optionally consists of a first end tappered inward toward a second end. Optionally, rotation of said second flange causes translational movement of the flange along the cylinder. A means for releasably locking the second flange is provided.