Patents by Inventor Gaurav D. SHAH

Gaurav D. SHAH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210290685
    Abstract: The present invention relates generally to methods for genetic modification of hematopoietic cells. In particular, the invention relates to use of Prostaglandin E2 (PGE2), poloxamer, and protamine sulfate to enhance transduction by a recombinant retroviral vector. The compositions and methods of the present disclosure are particularly suitable for gene therapy applications, including the treatment of monogenic genetic diseases and disorders.
    Type: Application
    Filed: July 30, 2019
    Publication date: September 23, 2021
    Inventors: Brian BEARD, Gaurav D. SHAH, Juan Antonio BUEREN RONCERO, Jose Carlos SEGOVIA SANZ, Paula RIO GALDO, Susana NAVARRO ORDONEZ, Elena ALMARZA NOVOA, Oscar QUINTANA BUSTAMANTE, Cristina MESA NUNEZ, Kenneth LAW, Kinnari PATEL
  • Publication number: 20170137523
    Abstract: The invention provides for the human antibodies that bind to human platelet-derived growth factor receptor alpha (PDGFR alpha), preferably olaratumab, for the treatment of gastrointestinal stromal tumors with PDGFR alpha mutations including D842V.
    Type: Application
    Filed: June 26, 2015
    Publication date: May 18, 2017
    Applicant: ImClone LLC
    Inventor: Gaurav D. SHAH
  • Publication number: 20170129958
    Abstract: Combination of human antibodies that bind to human platelet-derived growth factor receptor alpha (PDGFR alpha), preferably olaratumab, and doxorubicin as a medicament for the treatment of soft tissue sarcoma.
    Type: Application
    Filed: June 26, 2015
    Publication date: May 11, 2017
    Applicant: ImClone LLC
    Inventors: Nick LOIZOS, Gaurav D. SHAH