Patents by Inventor Gaurav Krishnamurthy

Gaurav Krishnamurthy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210338419
    Abstract: The present technology relates to modular valve replacement systems for treating valve-related cardiac disorders. In select embodiments, the modular valve replacement system includes a fixation device and a permanent valve assembly. The fixation device and the permanent valve assembly are delivered separately, enabling use of smaller delivery systems and facilitating less-invasive implant techniques. The fixation device is implanted first and provides a mounting fixture for the subsequently delivered permanent valve assembly. In some embodiments, the permanent valve assembly is at least partially mechanically isolated from the fixation device after the permanent valve assembly is attached to the fixation device. In some embodiments, the fixation device includes a temporary valve assembly that prevents regurgitation until the permanent valve assembly is implanted.
    Type: Application
    Filed: October 7, 2019
    Publication date: November 4, 2021
    Inventors: Hanson S. Gifford, III, James I. Fann, Matthew McClean, Gaurav Krishnamurthy, Vrad Levering, Neil Zimmerman
  • Publication number: 20210085462
    Abstract: Cardiac valve repair devices with coaptation members and multiple clip mechanisms and associated systems and methods are disclosed herein. A cardiac valve repair device configured in accordance with embodiments of the present technology can include, for example, an optional fixation member configured to engage tissue within a left atrium proximate to a native mitral valve, a coaptation member depending from the fixation member, and a plurality of clip mechanisms extending from a downstream portion of the coaptation member. The coaptation member can be positioned between the native leaflets and at least partially fill a space between the native leaflets. A first clip mechanism can engage a first portion of one of the native leaflets, and a second clip mechanism can engage another portion of the same native leaflet or an opposing native leaflet.
    Type: Application
    Filed: September 21, 2020
    Publication date: March 25, 2021
    Inventors: Hanson S. Gifford, III, Ben F. Brian, III, Matthew McLean, Gaurav Krishnamurthy, Neil Zimmerman, James I. Fann, Katie Miyashiro
  • Publication number: 20200289265
    Abstract: Cardiac valve repair devices with annuloplasty features and associated systems and methods are disclosed herein. A cardiac valve repair device configured in accordance with embodiments of the present technology can include, for example, an atrial fixation member configured to engage tissue within a left atrium proximate to a native mitral valve and a spring mechanism coupled to an inferior edge portion of the atrial fixation member. The spring mechanism has an extended state with a first length corresponding to a dimension of the atrial fixation member in a deployed state and a relaxed state with a shorter length corresponding to a desired dimension of the native valve annulus. When implanted, the spring mechanism contracts the atrial fixation member such that the native mitral annulus anchored to the atrial fixation member reduces in a cross-sectional dimension.
    Type: Application
    Filed: March 12, 2020
    Publication date: September 17, 2020
    Inventors: Hanson S. Gifford, III, Matt McLean, Gaurav Krishnamurthy, Neil Zimmerman
  • Publication number: 20200275974
    Abstract: Devices and minimally invasive methods for reducing the size of a cardiac valve annulus in a beating heart. Embodiments of the methods can include advancing an energy delivery catheter into the heart proximate a cardiac valve annulus, the energy delivery catheter having at least two electrodes. Then advancing the two electrodes such that the two electrodes pierce into the cardiac valve annulus at a distance from one another. The methods further include applying an approximating force to at least one of the two electrodes, thereby reducing the distance between the two electrodes, and applying energy between the at least two electrodes, thereby heating and shrinking the annulus in a direction of the approximating force.
    Type: Application
    Filed: September 14, 2018
    Publication date: September 3, 2020
    Inventors: Hanson S. Gifford, III, Matt McLean, Gaurav Krishnamurthy, James Fann, Doug Sutton
  • Publication number: 20200245998
    Abstract: Procedures may be performed on the heart after the installation of a mitral valve fixation device. In order to prepare the heart for such procedures, the fixation device may be removed or disabled in minimally invasive ways (e.g., through an endovascular procedure), without requiring open access to the heart. The fixation device may be partitioned so that one portion may remain attached to each leaflet of the mitral valve. In another example, the leaflets may be cut along the edges of the distal element(s) of the fixation device, so as to cut the fixation device from the leaflet(s). Systems and devices for performing such procedures endovascularly are disclosed. Fixation devices with improved access to a release harness are also disclosed.
    Type: Application
    Filed: April 23, 2020
    Publication date: August 6, 2020
    Inventors: Raghuveer Basude, Kent Dell, Arundhati Kabe, Gaurav Krishnamurthy, Michael F. Wei
  • Publication number: 20200222185
    Abstract: Coaptation assist device for repairing cardiac valves and associated systems and methods are disclosed herein. A coaptation assist device configured in accordance with embodiments of the present technology can include, for example, a fixation member configured to press against cardiac tissue proximate to a native valve annulus, and a stationary coaptation structure extending away from the fixation member. The coaptation structure can include an anterior surface configured to coapt with a first native leaflet during systole and a posterior surface configured to displace at least a portion of a second native leaflet. The device also includes at least one sensor configured to detect parameters associated with at least one of cardiac function and device functionality. The sensors can be pressure sensors configured to detect left atrial pressure and/or left ventricular pressure.
    Type: Application
    Filed: January 16, 2020
    Publication date: July 16, 2020
    Inventors: Arie Pieter Kappetein, James I. Fann, Hanson S. Gifford, III, Matthew McLean, Gaurav Krishnamurthy, Neil Zimmerman
  • Patent number: 10675036
    Abstract: Devices, systems, and methods for treating vascular defects are disclosed herein. One aspect of the present technology, for example, is directed toward an occlusive device that includes a first mesh having an expanded state in which it curves about a first axis to form a first band, and a second mesh having an expanded state in which it curves about a second axis different than the first axis to form a second band. The second band may be positioned radially inward of the first band such that the device includes first and second overlap regions in which the first band overlaps the second band.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: June 9, 2020
    Assignee: Covidien LP
    Inventors: Arturo Rosqueta, Gaurav Krishnamurthy, Jose Gonzalez, Patrick Quinn, Eric Yu
  • Patent number: 10667804
    Abstract: Procedures may be performed on the heart after the installation of a mitral valve fixation device. In order to prepare the heart for such procedures, the fixation device may be removed or disabled in minimally invasive ways (e.g., through an endovascular procedure), without requiring open access to the heart. The fixation device may be partitioned so that one portion may remain attached to each leaflet of the mitral valve. In another example, the leaflets may be cut along the edges of the distal element(s) of the fixation device, so as to cut the fixation device from the leaflet(s). Systems and devices for performing such procedures endovascularly are disclosed. Fixation devices with improved access to a release harness are also disclosed.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: June 2, 2020
    Assignee: Evalve, Inc.
    Inventors: Raghuveer Basude, Kent Dell, Arundhati Kabe, Gaurav Krishnamurthy, Michael F. Wei
  • Publication number: 20200138447
    Abstract: Devices, systems, and methods for treating vascular defects are disclosed herein. One aspect of the present technology, for example, is directed toward an occlusive device that includes a first mesh having an expanded state in which it curves about a first axis to form a first band, and a second mesh having an expanded state in which it curves about a second axis different than the first axis to form a second band. The second band may be positioned radially inward of the first band such that the device includes first and second overlap regions in which the first band overlaps the second band.
    Type: Application
    Filed: January 9, 2020
    Publication date: May 7, 2020
    Inventors: Arturo Rosqueta, Gaurav Krishnamurthy, Jose Gonzalez, Patrick Quinn, Eric Yu
  • Publication number: 20190059907
    Abstract: Devices, systems, and methods for treating vascular defects are disclosed herein. One aspect of the present technology, for example, is directed toward an occlusive device that includes a first mesh having an expanded state in which it curves about a first axis to form a first band, and a second mesh having an expanded state in which it curves about a second axis different than the first axis to form a second band. The second band may be positioned radially inward of the first band such that the device includes first and second overlap regions in which the first band overlaps the second band.
    Type: Application
    Filed: August 22, 2017
    Publication date: February 28, 2019
    Inventors: Arturo Rosqueta, Gaurav Krishnamurthy, Jose Gonzalez, Patrick Quinn, Eric Yu
  • Publication number: 20170143330
    Abstract: Procedures may be performed on the heart after the installation of a mitral valve fixation device. In order to prepare the heart for such procedures, the fixation device may be removed or disabled in minimally invasive ways (e.g., through an endovascular procedure), without requiring open access to the heart. The fixation device may be partitioned so that one portion may remain attached to each leaflet of the mitral valve. In another example, the leaflets may be cut along the edges of the distal element(s) of the fixation device, so as to cut the fixation device from the leaflet(s). Systems and devices for performing such procedures endovascularly are disclosed. Fixation devices with improved access to a release harness are also disclosed.
    Type: Application
    Filed: February 2, 2017
    Publication date: May 25, 2017
    Inventors: Raghuveer Basude, Kent Dell, Arundhati Kabe, Gaurav Krishnamurthy, Michael F. Wei
  • Patent number: 9572666
    Abstract: Procedures may be performed on the heart after the installation of a mitral valve fixation device. In order to prepare the heart for such procedures, the fixation device may be removed or disabled in minimally invasive ways (e.g., through an endovascular procedure), without requiring open access to the heart. The fixation device may be partitioned so that one portion may remain attached to each leaflet of the mitral valve. In another example, the leaflets may be cut along the edges of the distal element(s) of the fixation device, so as to cut the fixation device from the leaflet(s). Systems and devices for performing such procedures endovascularly are disclosed. Fixation devices with improved access to a release harness are also disclosed.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: February 21, 2017
    Assignee: Evalve, Inc.
    Inventors: Raghuveer Basude, Kent Dell, Arundhati Kabe, Gaurav Krishnamurthy, Michael F. Wei
  • Patent number: 9149271
    Abstract: A device and method for treatment of hemorrhoids, in which the devices includes: a housing insertable into the rectum; a tissue port configured to receive a tissue segment containing at least a portion of a hemorrhoidal blood vessel; opposing needle chambers including at least one pair of corresponding needles coupled by a suture in which the pair of corresponding needles are substantially opposite to one another and in an active position substantially aligned with the tissue segment; a needle driver that advances the pair of corresponding needles through the tissue segment to encircle a portion of the hemorrhoidal blood vessel with the suture, thereby ligating the hemorrhoidal blood vessel; and an actuator coupled to at least one of the needle chambers that actuates the needle chambers such that another pair of corresponding needles is in the active position.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: October 6, 2015
    Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD, JR. UNIVERSITY
    Inventors: Jacob S. Brenner, Gregory A. Magee, Angelo F. Szychowski, Gaurav Krishnamurthy, Steven K. Jacobs
  • Publication number: 20150257883
    Abstract: Procedures may be performed on the heart after the installation of a mitral valve fixation device. In order to prepare the heart for such procedures, the fixation device may be removed or disabled in minimally invasive ways (e.g., through an endovascular procedure), without requiring open access to the heart. The fixation device may be partitioned so that one portion may remain attached to each leaflet of the mitral valve. In another example, the leaflets may be cut along the edges of the distal element(s) of the fixation device, so as to cut the fixation device from the leaflet(s). Systems and devices for performing such procedures endovascularly are disclosed. Fixation devices with improved access to a release harness are also disclosed.
    Type: Application
    Filed: March 17, 2014
    Publication date: September 17, 2015
    Applicant: Evalve, Inc.
    Inventors: Raghuveer Basude, Kent Dell, Arundhati Kabe, Gaurav Krishnamurthy, Michael F. Wei
  • Publication number: 20120130403
    Abstract: A device and method for treatment of hemorrhoids, in which the devices includes: a housing insertable into the rectum; a tissue port configured to receive a tissue segment containing at least a portion of a hemorrhoidal blood vessel; opposing needle chambers including at least one pair of corresponding needles coupled by a suture in which the pair of corresponding needles are substantially opposite to one another and in an active position substantially aligned with the tissue segment; a needle driver that advances the pair of corresponding needles through the tissue segment to encircle a portion of the hemorrhoidal blood vessel with the suture, thereby ligating the hemorrhoidal blood vessel; and an actuator coupled to at least one of the needle chambers that actuates the needle chambers such that another pair of corresponding needles is in the active position.
    Type: Application
    Filed: November 22, 2010
    Publication date: May 24, 2012
    Inventors: Jacob S. Brenner, Gregory A. Magee, Angelo F. Szychowski, Gaurav Krishnamurthy, Steven K. Jacobs