Patents by Inventor Gavin Rush
Gavin Rush has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11603547Abstract: The present invention provides improved DNA polymerases, in particular, type A DNA polymerases, that may be better suited for applications in recombinant DNA technologies. Among other things, the present invention provides modified DNA polymerases derived from directed evolution experiments designed to select mutations that confer advantageous phenotypes under conditions used in industrial or research applications.Type: GrantFiled: February 22, 2021Date of Patent: March 14, 2023Assignee: Kapa Biosystems, Inc.Inventors: William Bourn, Maryke Appel, Gavin Rush, John Foskett, Paul J. McEwan
-
Publication number: 20210180102Abstract: The present invention provides improved DNA polymerases, in particular, type A DNA polymerases, that may be better suited for applications in recombinant DNA technologies. Among other things, the present invention provides modified DNA polymerases derived from directed evolution experiments designed to select mutations that confer advantageous phenotypes under conditions used in industrial or research applications.Type: ApplicationFiled: February 22, 2021Publication date: June 17, 2021Inventors: William Bourn, Maryke Appel, Gavin Rush, John Foskett, Paul J. McEwan
-
Patent number: 10961555Abstract: The present invention provides improved DNA polymerases, in particular, type A DNA polymerases, that may be better suited for applications in recombinant DNA technologies. Among other things, the present invention provides modified DNA polymerases derived from directed evolution experiments designed to select mutations that confer advantageous phenotypes under conditions used in industrial or research applications.Type: GrantFiled: May 3, 2018Date of Patent: March 30, 2021Assignee: Kapa Biosystems, Inc.Inventors: William Bourn, Maryke Appel, Gavin Rush, John Foskett, Paul J. McEwan
-
Patent number: 10457968Abstract: The present invention provides improved DNA polymerases, in particular, type A DNA polymerases, that may be better suited for applications in recombinant DNA technologies. Among other things, the present invention provides modified DNA polymerases derived from directed evolution experiments designed to select mutations that confer advantageous phenotypes under conditions used in industrial or research applications.Type: GrantFiled: November 3, 2009Date of Patent: October 29, 2019Assignee: Kapa Biosystems, Inc.Inventors: William Bourn, Maryke Appel, Gavin Rush, John Foskett, Paul McEwan
-
Publication number: 20190100783Abstract: The present invention provides improved DNA polymerases, in particular, type A DNA polymerases, that may be better suited for applications in recombinant DNA technologies. Among other things, the present invention provides modified DNA polymerases derived from directed evolution experiments designed to select mutations that confer advantageous phenotypes under conditions used in industrial or research applications.Type: ApplicationFiled: December 21, 2018Publication date: April 4, 2019Inventors: William Bourn, Maryke Appel, Gavin Rush, John Foskett, Paul J. McEwan
-
Publication number: 20170051326Abstract: The present invention provides improved DNA polymerases, in particular, type A DNA polymerases, that may be better suited for applications in recombinant DNA technologies. Among other things, the present invention provides modified DNA polymerases derived from directed evolution experiments designed to select mutations that confer advantageous phenotypes under conditions used in industrial or research applications.Type: ApplicationFiled: September 22, 2016Publication date: February 23, 2017Inventors: William Bourn, Maryke Appel, Gavin Rush, John Foskett, Paul J. McEwan
-
Patent number: 9388396Abstract: The present invention provides, among other things, chimeric DNA polymerases containing heterologous domains having sequences derived from at least two DNA polymerases that have at least one distinct functional characteristics (e.g., elongation rate, processivity, error rate or fidelity, salt tolerance or resistance) and methods of making and using the same. In some embodiments, the present invention can combine desired functional characteristics (e.g., high processivity; high elongation rate; thermostability; resistance to salt, PCR additives (e.g., PCR enhancers) and other impurities; and high fidelity) of different DNA polymerases in a chimeric polymerase.Type: GrantFiled: May 5, 2014Date of Patent: July 12, 2016Assignee: Kapa Biosystems, Inc.Inventors: Bjarne Faurholm, Paul McEwan, William Bourn, Gavin Rush
-
Patent number: 9023633Abstract: The present invention provides, among other things, chimeric DNA polymerases containing heterologous domains having sequences derived from at least two DNA polymerases that have at least one distinct functional characteristics (e.g., elongation rate, processivity, error rate or fidelity, salt tolerance or resistance) and methods of making and using the same. In some embodiments, the present invention can combine desired functional characteristics (e.g., high processivity; high elongation rate; thermostability; resistance to salt, PCR additives (e.g., PCR enhancers) and other impurities; and high fidelity) of different DNA polymerases in a chimeric polymerase.Type: GrantFiled: November 3, 2009Date of Patent: May 5, 2015Assignee: Kapa BiosystemsInventors: Bjarne Faurholm, Paul McEwan, William Bourn, Gavin Rush
-
Publication number: 20140363848Abstract: The present invention provides, among other things, chimeric DNA polymerases containing heterologous domains having sequences derived from at least two DNA polymerases that have at least one distinct functional characteristics (e.g., elongation rate, processivity, error rate or fidelity, salt tolerance or resistance) and methods of making and using the same. In some embodiments, the present invention can combine desired functional characteristics (e.g., high processivity; high elongation rate; thermostability; resistance to salt, PCR additives (e.g., PCR enhancers) and other impurities; and high fidelity) of different DNA polymerases in a chimeric polymerase.Type: ApplicationFiled: May 5, 2014Publication date: December 11, 2014Applicant: KAPA BIOSYSTEMS, INC.Inventors: Bjarne FAURHOLM, Paul MCEWAN, William BOURN, Gavin RUSH
-
Publication number: 20120115188Abstract: The present invention provides, among other things, chimeric DNA polymerases containing heterologous domains having sequences derived from at least two DNA polymerases that have at least one distinct functional characteristics (e.g., elongation rate, processivity, error rate or fidelity, salt tolerance or resistance) and methods of making and using the same. In some embodiments, the present invention can combine desired functional characteristics (e.g., high processivity; high elongation rate; thermostability; resistance to salt, PCR additives (e.g., PCR enhancers) and other impurities; and high fidelity) of different DNA polymerases in a chimeric polymerase.Type: ApplicationFiled: November 3, 2009Publication date: May 10, 2012Applicant: KAPA BIOSYSTEMSInventors: Bjarne Faurholm, Paul McEwan, William Bourn, Gavin Rush
-
Publication number: 20110281305Abstract: The present invention provides improved DNA polymerases, in particular, type A DNA polymerases, that may be better suited for applications in recombinant DNA technologies. Among other things, the present invention provides modified DNA polymerases derived from directed evolution experiments designed to select mutations that confer advantageous phenotypes under conditions used in industrial or research applications.Type: ApplicationFiled: November 3, 2009Publication date: November 17, 2011Applicant: KAPABIOSYSTEMSInventors: William Bourn, Maryke Appel, Gavin Rush, John Foskett, Paul McEwan