Abstract: Methods, systems, and apparatus, including computer programs encoded on a storage device, for guiding weapon systems to targets are disclosed. A method includes obtaining sensor data from one or more sensors mounted to a weapon system; providing the sensor data as input to a target model, the target model being an artificial intelligence model trained to detect a particular type of object within a set of sensor data from one or more particular types of sensors and to provide output that is decipherable by flight control systems to control navigation operations; obtaining output data from the target model; providing the output data from the target model to a flight control system of the weapon system; and controlling operation of one or more control surfaces of the weapon system, responsive to the output data to control a trajectory of the weapon system.