Patents by Inventor Gayle M. Webber

Gayle M. Webber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing steroidal 3-oxo-4,6-dienes such as 17-hydroxy-3-oxo-17.alpha.-pregna-4,6-diene-21-carboxylic acid.gamma.-lactone
    Patent number: 4155906
    Abstract: A process for preparing 17-hydroxy-3-oxo-17.alpha.-pregna-4,6-diene-21-carboxylic acid .gamma.-lactone by contacting 17-hydroxy-3-oxy-17.alpha.-pregna-3,5-diene-21-carboxylic acid .gamma.-lactone with an appropriate halogenating agent in the presence of an amine base, the corresponding hydrohalide salt thereof, and approximately 1-2 molar equivalents (relative to the lactonic starting material) of water, using a cold solvent as the contact medium, and heating the resultant mixture with a dehydrohalogenating agent, is disclosed.
    Type: Grant
    Filed: December 2, 1977
    Date of Patent: May 22, 1979
    Assignee: G. D. Searle & Co.
    Inventors: Hugh L. Dryden, Jr., Gayle M. Webber