Patents by Inventor Gayle Stephenson

Gayle Stephenson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYMER FACTOR IX MOIETY CONJUGATES
    Publication number: 20210023186
    Abstract: Conjugates of a Factor IX moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided (among other things) are compositions comprising the conjugates, methods of making the conjugates, and methods of administering to a patient compositions comprising the conjugates.
    Type: Application
    Filed: October 5, 2020
    Publication date: January 28, 2021
    Inventors: Mary J. Bossard, Gayle Stephenson-Phillips
  • Conjugates of an anti-TNF-alpha antibody
    Patent number: 10232042
    Abstract: Conjugates of an anti-TNF antibody and one or more nonpeptidic water-soluble polymers are provided. Typically, the nonpeptidic water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, and methods of administering compositions to a patient.
    Type: Grant
    Filed: March 27, 2017
    Date of Patent: March 19, 2019
    Assignee: Nektar Therapeutics
    Inventors: Mary J. Bossard, Gayle Stephenson-Phillips
  • CONJUGATES OF AN ANTI-TNF-ALPHA ANTIBODY
    Publication number: 20170196975
    Abstract: Conjugates of an anti-TNF antibody and one or more nonpeptidic water-soluble polymers are provided. Typically, the nonpeptidic water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, and methods of administering compositions to a patient.
    Type: Application
    Filed: March 27, 2017
    Publication date: July 13, 2017
    Inventors: Mary J. Bossard, Gayle Stephenson-Phillips
  • Conjugates of an anti-TNF-alpha antibody
    Patent number: 9636412
    Abstract: Conjugates of an anti-TNF antibody and one or more nonpeptidic water soluble polymers are provided. Typically, the nonpeptidic water soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, and methods of administering compositions to a patient.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: May 2, 2017
    Assignee: Nektar Therapeutics
    Inventors: Mary J. Bossard, Gayle Stephenson-Phillips
  • POLYMER FACTOR IX MOIETY CONJUGATES
    Publication number: 20170035896
    Abstract: Conjugates of a Factor IX moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided (among other things) are compositions comprising the conjugates, methods of making the conjugates, and methods of administering to a patient compositions comprising the conjugates.
    Type: Application
    Filed: May 17, 2016
    Publication date: February 9, 2017
    Inventors: Mary J. Bossard, Gayle Stephenson Phillips
  • Von willebrand factor- and factor VIII-polymer conjugates having a releasable linkage
    Patent number: 9493544
    Abstract: The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: November 15, 2016
    Assignees: Nektar Therapeutics, Baxalta Incorporated, Baxalta GmbH
    Inventors: Mary J. Bossard, Gayle Stephenson, Zhihao Fang, Harold Zappe, Stacy Mitchell, Ping Zhang, Friedrich Scheiflinger, Peter Turecek, Juergen Siekmann, Katalin Varadi, Herbert Gritsch
  • Polymer factor IX moiety conjugates
    Patent number: 9347054
    Abstract: Conjugates of a Factor IX moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is polyethylene glycol) or a derivative thereof. Also provided (among other things) are compositions comprising the conjugates, methods of making the conjugates, and methods of administering to a patient compositions comprising the conjugates.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: May 24, 2016
    Assignee: Nektar Therapeutics
    Inventors: Mary J. Bossard, Gayle Stephenson Phillips
  • CONJUGATES OF AN ANTI-TNF-ALPHA ANTIBODY
    Publication number: 20160030587
    Abstract: Conjugates of an anti-TNF antibody and one or more nonpeptidic water soluble polymers are provided. Typically, the nonpeptidic water soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, and methods of administering compositions to a patient.
    Type: Application
    Filed: August 5, 2015
    Publication date: February 4, 2016
    Inventors: Mary J. Bossard, Gayle Stephenson-Phillips
  • Conjugates of an anti-TNF-? antibody
    Patent number: 9101670
    Abstract: Conjugates of an anti-TNF antibody and one or more nonpeptidic water soluble polymers are provided. Typically, the nonpeptidic water soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, and methods of administering compositions to a patient.
    Type: Grant
    Filed: April 6, 2007
    Date of Patent: August 11, 2015
    Assignee: Nektar Therapeutics
    Inventors: Mary J. Bossard, Gayle Stephenson
  • POLYMER FACTOR IX MOIETY CONJUGATES
    Publication number: 20140141483
    Abstract: Conjugates of a Factor IX moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is polyethylene glycol) or a derivative thereof. Also provided (among other things) are compositions comprising the conjugates, methods of making the conjugates, and methods of administering to a patient compositions comprising the conjugates.
    Type: Application
    Filed: November 8, 2013
    Publication date: May 22, 2014
    Applicant: Nektar Therapeutics
    Inventors: Mary J. Bossard, Gayle Stephenson
  • Polymer-factor IX moiety conjugates
    Patent number: 8586711
    Abstract: Conjugates of a Factor IX moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided (among other things) are compositions comprising the conjugates, methods of making the conjugates, and methods of administering to a patient compositions comprising the conjugates.
    Type: Grant
    Filed: December 15, 2009
    Date of Patent: November 19, 2013
    Assignee: Nektar Therapeutics
    Inventors: Mary J. Bossard, Gayle Stephenson
  • Factor IX moiety-polymer conjugates having a releasable linkage
    Patent number: 8507653
    Abstract: The present invention provides Factor IX moiety-polymer conjugates having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided.
    Type: Grant
    Filed: December 27, 2007
    Date of Patent: August 13, 2013
    Assignee: Nektar Therapeutics
    Inventors: Mary J. Bossard, Gayle Stephenson
  • VON WILLEBRAND FACTOR- AND FACTOR VIII-POLYMER CONJUGATES HAVING A RELEASABLE LINKAGE
    Publication number: 20130012442
    Abstract: The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 10, 2013
    Applicants: NEKTAR THERAPEUTICS, Baxter Healthcare SA, Baxter International Inc.
    Inventors: Mary J. Bossard, Gayle Stephenson, Zhihao Fang, Harold Zappe, Stacy Mitchell, Ping Zhang, Friedrich Scheiflinger, Peter Turecek, Juergen Siekmann, Katalin Varadi, Herbert Gritsch
  • Von Willebrand factor- and factor VIII-polymer conjugates having a releasable linkage
    Patent number: 8349800
    Abstract: The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: January 8, 2013
    Assignees: Nektar Therapeutics, Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Mary J. Bossard, Gayle Stephenson, Zhihao Fang, Harold Zappe, Stacy Mitchell, Ping Zhang, Friedrich Scheiflinger, Peter Turecek, Juergen Siekmann, Katalin Varadi, Herbert Gritsch
  • Von Willebrand Factor- and Factor VIII-Polymer Conjugates Having a Releasable Linkage
    Publication number: 20120142594
    Abstract: The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided.
    Type: Application
    Filed: February 10, 2012
    Publication date: June 7, 2012
    Applicants: Baxter International Inc., NEKTAR THERAPEUTICS
    Inventors: Mary J. Bossard, Gayle Stephenson, Zhihao Fang, Harold Zappe, Stacy Mitchell, Ping Zhang, Friedrich Scheiflinger, Peter Turecek, Juergen Siekmann, Katalin Varadi, Herbert Gritsch
  • von Willebrand factor- and factor VIII-polymer conjugates having a releasable linkage
    Patent number: 8133865
    Abstract: The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided.
    Type: Grant
    Filed: December 27, 2007
    Date of Patent: March 13, 2012
    Assignees: Nektar Therapeutics, Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Mary J. Bossard, Gayle Stephenson, Zhihao Fang, Harold Zappe, Stacy Mitchell, Ping Zhang, Friedrich Scheiflinger, Peter Turecek, Juergen Siekmann, Katalin Varadi, Herbert Gritsch
  • POLYMER FACTOR IX MOIETY CONJUGATES
    Publication number: 20100249033
    Abstract: Conjugates of a Factor IX moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided (among other things) are compositions comprising the conjugates, methods of making the conjugates, and methods of administering to a patient compositions comprising the conjugates.
    Type: Application
    Filed: June 7, 2010
    Publication date: September 30, 2010
    Applicant: Nektar Therapeutics
    Inventors: Mary J. Bossard, Gayle Stephenson
  • Conjugates of an EPO Moiety and a Polymer
    Publication number: 20100160610
    Abstract: Conjugates of an EPO moiety and one or more non-peptidic water-soluble polymers are provided. Typically, the non-peptidic water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided are compositions comprising such conjugates, methods of making conjugates, and methods of administering compositions comprising such conjugates to a patient.
    Type: Application
    Filed: January 21, 2010
    Publication date: June 24, 2010
    Applicant: Nektar Therapeutics
    Inventors: Mary J. Bossard, Gayle Stephenson
  • POLYMER FACTOR IX MOIETY CONJUGATES
    Publication number: 20100137511
    Abstract: Conjugates of a Factor IX moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided (among other things) are compositions comprising the conjugates, methods of making the conjugates, and methods of administering to a patient compositions comprising the conjugates.
    Type: Application
    Filed: December 15, 2009
    Publication date: June 3, 2010
    Applicant: Nektar Therapeutics
    Inventors: Mary J. Bossard, Gayle Stephenson
  • POLYMER FACTOR IX MOIETY CONJUGATES
    Publication number: 20100130428
    Abstract: Conjugates of a Factor IX moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided (among other things) are compositions comprising the conjugates, methods of making the conjugates, and methods of administering to a patient compositions comprising the conjugates.
    Type: Application
    Filed: December 15, 2009
    Publication date: May 27, 2010
    Applicant: Nektar Therapeutics
    Inventors: Mary J. Bossard, Gayle Stephenson