Patents by Inventor Gayle Yamamoto

Gayle Yamamoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Beta-1,3-galactosyltransferase homologs
    Publication number: 20030175922
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for znssp2, a novel member of the galactosyltransferase family. The polypeptides, and polynucleotides encoding them, are cell-cell interaction and glycoprotein synthesis modulating and may be used for delivery and therapeutics. The present invention also includes antibodies to the znssp2 polypeptides.
    Type: Application
    Filed: June 21, 2002
    Publication date: September 18, 2003
    Applicant: ZymoGenetics, Inc.
    Inventors: Darrell C. Conklin, Gayle Yamamoto, Stephen R. Jaspers, Zeren Gao
  • Galactosyltransferase homolog, ZNSSP11
    Publication number: 20030104398
    Abstract: Novel soluble, and membrane bound, Beta1,3 galactosyltransferase polypeptides, polynucleotides encoding the polypeptides, antibodies and related compositions and methods are disclosed. The polypeptides may be used for detecting anti-complementary molecules, agonists and antagonists. The polypeptides, polynucleotides and antibodies may also be used in methods that modulate cell-cell interactions, and glycoprotein and glycolipid modifications.
    Type: Application
    Filed: November 2, 2001
    Publication date: June 5, 2003
    Inventors: David A. Adler, James L. Holloway, Gayle Yamamoto
  • Anti-angiogenic intestinal peptides, zdint5
    Publication number: 20020142439
    Abstract: The present invention relates to polynucleotide and polypeptide molecules, and variants thereof, for zdint5, a novel member of the Disintegrin Proteases. The polypeptides, and polynucleotides encoding them, are cell-cell interaction modulating and may be used for delivery and therapeutics. The present invention also includes antibodies to the zdint5 polypeptides.
    Type: Application
    Filed: February 9, 2001
    Publication date: October 3, 2002
    Inventors: James L. Holloway, Paul O. Sheppard, Gayle Yamamoto
  • Human beta-1,3-galactosyltransferase
    Publication number: 20020098564
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for znssp6, a novel member of the galactosyltransferase family. The polypeptides, and polynucleotides encoding them, are cell-cell interaction and glycoprotein synthesis modulating and may be used for delivery and therapeutics. The present invention also includes antibodies to the znssp6 polypeptides.
    Type: Application
    Filed: October 22, 2001
    Publication date: July 25, 2002
    Applicant: ZymoGenetics, Inc.
    Inventors: Darrell C. Conklin, Gayle Yamamoto, Zeren Gao, Stephen R. Jaspers
  • Beta-1,3-galactosyltransferase homologs
    Patent number: 6416988
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for znssp2, a novel member of the galactosyltransferase family. The polypeptides, and polynucleotides encoding them, are cell-cell interaction and glycoprotein synthesis modulating and may be used for delivery and therapeutics. The present invention also includes antibodies to the znssp2 polypeptides.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: July 9, 2002
    Assignee: Zymogenetics, Inc.
    Inventors: Darrell C. Conklin, Gayle Yamamoto, Stephen R. Jaspers, Zeren Gao
  • Beta-1,3-galactosyltransferase homolog, ZNSSP6
    Patent number: 6361985
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for znssp6, a novel member of the galactosyltransferase family. The polypeptides, and polynucleotides encoding them, are cell-cell interaction and glycoprotein synthesis modulating and may be used for delivery and therapeutics. The present invention also includes antibodies to the znssp6 polypeptides.
    Type: Grant
    Filed: January 12, 2000
    Date of Patent: March 26, 2002
    Assignee: ZymoGenetics, Inc.
    Inventors: Darrell C. Conklin, Gayle Yamamoto, Zeren Gao, Stephen R. Jaspers
  • Monoclonal antibody methods and compositions specific for single antigens in antigen aggregates
    Patent number: 4675386
    Abstract: Methods and compositions are provided for producing monoclonal antibodies capable of distinguishing between antigenic aggregates, which are differentiated by one or a small number of antigenic determinants. The method involves immunization of a mammal to produce spleen cells which are fused with a cell line which is stable in vitro. The hybridized cells are then dispensed into culture wells at a density level which encourages the production of one colony per well. Autologous antigenic aggregates are employed for screening to distinguish the antibodies which discriminate between the antigenic aggregates. Particularly, mice are hyperimmunized with a homogeneous population of T-cells, the immunized mice killed and the spleens removed. The spleen cells are fused with mouse myeloma cells and the resulting hybrids plated at a relatively low density in culture wells. Plates containing fewer than 30% hybrid positive wells are found to have primarily one colony per well.
    Type: Grant
    Filed: May 19, 1983
    Date of Patent: June 23, 1987
    Assignee: Regents of the University of California
    Inventors: Ivor Royston, John Majda, Gayle Yamamoto