Abstract: Examples of the present disclosure provide a method and a device for prompting to select a new file in Instant Messaging (IM). The method includes: receiving, by an IM client, a request for selecting a file to be transmitted; determining, by the IM client, a new file is obtained within a predefined time period before receiving the request; and prompting, by the IM client, whether to select the new file to be transmitted. By employing the technical solution of the present disclosure, selection and transmission of new files, such as, pictures, audios, videos, documents may be more convenient, efficiency may be higher, and user experience may also be improved.

Abstract: This invention concerns an enzymatic reagent for measuring the analyte concentration in a patient by determination of oxidation rate of a reduced coenzyme. Said reagent is stabilized by the coenzyme reduction system which makes the reduced coenzyme in the reagent regenerate continuously throughout a long storage. This coenzyme reduction system comprises an enzyme having high specificity for said substrate, which results that the quantity of enzyme and substrate originally used in the reagent is reduced and the stability of reagent is improved. The reagent is a sole liquid. An essential part of the invention is a reagent to determine the anlytes for example aspartate aminotransfase, alanine aminotransferase and urea.