Abstract: A touch display panel includes: a base substrate, including a display area and a peripheral area on at least one side of the display area; pixel units in the display area, including a pixel driving circuit and a light-emitting element electrically connected to each other; touch electrodes in the display area; a touch wire electrically connected to at least one touch electrode, at least part of which extends to the peripheral area; a touch lead in the peripheral area, where the touch lead and the touch wire are in different conductive layers; and a contact groove in the peripheral area, where the touch wire and the touch lead are in contact in the contact groove, where the touch wire has a first touch wire portion in the contact groove, and the first touch wire portion extends obliquely with respect to an upper surface of the base substrate.

Abstract: A display substrate and a display device. The display substrate includes a base, an insulating layer, a crack barrier structure, and a signal line. The crack barrier structure is located in a peripheral area, and at least a part of an orthographic projection of the crack barrier structure onto the base extends in an extension direction of a boundary of a display area. The crack barrier structure includes: a groove structure and a blocking portion, the groove structure is in the insulating layer, and a part of the blocking portion is located in the groove structure. The signal line is located at the peripheral area, and includes a top surface facing away from the base, and a side surface located between the top surface and the base, and at least a part of the side surface away from the display area is between the blocking portion and the groove structure.

Abstract: The use of a mitoxantrone preparation in the preparation of a drug for diagnosing and treating breast cancer. Provided is the use of mitoxantrone and/or a pharmaceutically acceptable salt thereof in the preparation of a lymphatic tracer in a disease associated with breast resection. No local or systemic toxic and side effects are seen after local injection of the preparation, suggesting that the preparation has good tolerance, effectiveness and safety, which provides a new treatment idea for thoroughly curing breast cancer in a breast cancer patient.

Abstract: A method for producing hot water and a device especially for carrying out the method are provided. The method utilizes combined heat resources of solar energy and heat pump in the manner of heating water at multiple stages and accumulating energy. The device comprises solar energy collector, heat pump, electrical heater, water tank, and control unit. The device also includes water-heating tanks with multiple stages. A heating means with multiple stages at different temperatures is formed either by the solar energy collector or by the collector and the heat pump. The outputting end of the two or more heating stages constituted by the solar energy collector or by the collector and the heat pump is connected through ducts to the corresponding water-heating tanks. A predetermined amount of produced water heated at multiple stages is respectively stored in the water-heating tanks.

Abstract: The present invention discloses a variable temperature air-conditioning method using underground reservoir and water-source heat pump with energy-storage and its specialized equipment, which includes a geothermal heat exchanging cycling loop and an air-conditioning heat exchanging cycling loop, wherein the air-conditioning heat exchanging cycling loop includes a variable temperature air-conditioning heat exchanging cycling loop. In the geothermal heat exchanging cycling loop, the water-source heat pump exchanges energy with energy-storage tanks, and in the air-conditioning heat exchanging cycling loop, the energy-storage tanks exchanges energy with an air-conditioning load loop.